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Once or twice daily versus three times daily amoxicillin with or without clavulanate for the treatment of acute otitis media

  • Protocol
  • Intervention

Authors

  • S Thanaviratananich,

  • P Watanasapt,

  • M Laopaiboon


Prof Sanguansak Thanaviratananich, Assistant Professor, Department of Otolaryngology, Faculty of Medicine, Khon Kaen University, 123 Friendship Road, Khon Kaen, 40002, THAILAND. sanguans@kku.ac.th.

Abstract

This is the protocol for a review and there is no abstract. The objectives are as follows:

(1) To compare the effectiveness of amoxicillin with or without clavulanate between once or twice daily doses, with three or four times daily doses for the treatment of acute otitis media in children.
(2) To compare the complication rates between once or twice daily doses with three or four times daily doses.
(3) To compare the adverse reactions between the dosing intervals.