This is the protocol for a review and there is no abstract. The objectives are as follows:
1.To determine the efficacy of aripiprazole, either alone or in combination with other antimanic drug treatments, compared to placebo or other drug treatment in alleviating the acute symptoms of manic or mixed episodes.
2.To review acceptability of treatment with aripiprazole.
3. To investigate the adverse effects of aripiprazole treatment.
4.To determine overall mortality rates on aripiprazole treatment.