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Intervention Protocol

Interferon beta for secondary progressive multiple sclerosis

  1. G PA Rice,
  2. GC Ebers,
  3. S Fredrikson,
  4. D Mason,
  5. F Tesser,
  6. G Filippini

Editorial Group: Cochrane Multiple Sclerosis Group

Published Online: 24 JAN 2005

DOI: 10.1002/14651858.CD005181


How to Cite

Rice GPA, Ebers GC, Fredrikson S, Mason D, Tesser F, Filippini G. Interferon beta for secondary progressive multiple sclerosis (Protocol). Cochrane Database of Systematic Reviews 2005, Issue 1. Art. No.: CD005181. DOI: 10.1002/14651858.CD005181.

Author Information

*Prof George PA Rice, Clinical Neurological Sciences, University of Western Ontario, 339 Windermere Road, London, Ontario, N6A 5A5, CANADA. grice@uwo.ca.

Publication History

  1. Publication Status: Unchanged
  2. Published Online: 24 JAN 2005

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Abstract

  1. Top of page
  2. Abstract

This is the protocol for a review and there is no abstract. The objectives are as follows:

The primary question is whether interferon beta is more effective than placebo in decreasing the number of SPMS patients who experience disability progression during follow-up. We also aim to evaluate the incidence and seriousness of side effects and adverse events.

The secondary objectives are to examine the effect of interferon beta on relapses during follow-up, on patient activities of daily living and quality of life, and reducing the need for other treatments. We will also evaluate change in MRI parameters during follow-up.