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Herbal preparations for uterine fibroids

  1. Jian Ping Liu1,*,
  2. Hong Yang2,
  3. Yun Xia3,
  4. Francesco Cardini4

Editorial Group: Cochrane Gynaecology and Fertility Group

Published Online: 30 APR 2013

Assessed as up-to-date: 28 FEB 2013

DOI: 10.1002/14651858.CD005292.pub3


How to Cite

Liu JP, Yang H, Xia Y, Cardini F. Herbal preparations for uterine fibroids. Cochrane Database of Systematic Reviews 2013, Issue 4. Art. No.: CD005292. DOI: 10.1002/14651858.CD005292.pub3.

Author Information

  1. 1

    Beijing University of Chinese Medicine, Centre for Evidence-Based Chinese Medicine, Beijing, China

  2. 2

    Beijing University of Chinese Medicine, Graduate School, Beijing, China

  3. 3

    Beijing University of Chinese Medicine Subsidiary Dongfang Hospital, Science of Education, Beijing, China

  4. 4

    Regional Healthcare and Social Agency of Emilia Romagna, Bologna, Emilia Romagna, Italy

*Jian Ping Liu, Centre for Evidence-Based Chinese Medicine, Beijing University of Chinese Medicine, 11 Bei San Huan Dong Lu, Chaoyang District, Beijing, 100029, China. jianping_l@hotmail.com. jianping@fagmed.uit.no.

Publication History

  1. Publication Status: New search for studies and content updated (no change to conclusions)
  2. Published Online: 30 APR 2013

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References

References to studies included in this review

  1. References to studies included in this review
  2. References to studies excluded from this review
  3. Additional references
Deng XL 2010 {published data only}
  • Zheng XL, Li CR. Clinical observation of Guizhi Fuling capsule combined mifepristone treating 33 cases of uterine myoma. Hebei Journal of Traditional Chinese Medicine 2010;32(11):1670-1.
Dong M 2011 {published data only}
  • Dong M. Clinical research of Guizhi Fuling capsule combined leuprorelin treating premenopause uterine myoma. China Healthcare Innovation 2011;6(19):69-70.
Fu WJ 2005 {published data only}
  • Fu WJ, Ni J, Zheng LJ, Wang XF. [Observation on therapeutic effects of small dosage of Tripterygium Wilfordii Hook for treatment of uterine leiomyoma]. Journal of Hebei North University (Medical Edition) 2005;22(1):46-8.
Gu HH 2011 {published data only}
  • Gu HH, Hu QY. [Effect of integrated Chinese and western medicine in treating uterine myoma]. Strait Pharmaceutical Journal 2011;23(4):126-7.
Hazlina 2005 {published data only}
  • Hazlina NNH, Pazudin MI, Nor Aliza AG, Mohsin Sahil SJ. Clinical study to compare the efficacy and adverse effects of Nona Roguy herbal formulation and gonadotrophin releasing hormone agonist (GnRH) in the treatment of uterine fibroids. International Medical Journal 2005;12(4):295-302.
Lai XL 2010 {published data only}
  • Lai XL, Zheng LZ,  Ma XJ. [Gongliuqing capsule treated 94 cases of uterine myoma]. Jiangxi Journal of Traditional Chinese Medicine 2010;41(328):46-7.
Liu LY 2010 {published data only}
  • Liu LY. [Clinical research of Gongliuqing capsule combined with mifepristone for treating uterine myoma]. China Higher Medical Education 2010;23(12):140-1.
Liu Y 2009 {published data only}
  • Liu Y. [Observation of efficacy on combined therapy of mifepristone and Chinese herbal medicine on 30 cases of hysteromyoma]. World Journal of Integrated Traditional and Western Medicine 2009;4(4):268-70.
Lu HJ 2010 {published data only}
  • Lu HJ. [Curative effect observation of mifepristone combined with Guilin Fuling capsule treating uterine myoma]. Chinese Journal of Clinical Rational Drug Use 2010;3(17):49-50.
Lu JX 2007 {published data only}
  • Lu JX. [Comparison of Huoxue Sanjie decoction with mifepristone in the treatment of uterine fibroids]. Shandong Journal of Medicine and Pharmacology 2007;47(19):109-10.
Luo SQ 2010 {published data only}
  • Luo SQ. [Clinical observation of Jiliu decoction combined with mifepristone in the treatment of uterine myoma]. Journal of Emergency in Traditional Chinese Medicine 2010;19(6):943-4.
Mao CX 2012 {published data only}
  • Mao CX, Cai RR, Wang XP, Wu YL. [Curative effects on treating premenopause hysteromyoma by mifepristone with Guizhi Fuling capsule]. Chinese Archives of Traditional Chinese Medicine 2012;30(3):665-7.
Mao XG 2012 {published data only}
  • Mao XG, Fang SS. [Clinical observation of Guizhi Fuling capsule combined mifepristone for treating 33 cases of uterine myoma]. Asia-Pacific Traditional Medicine 2012;8(4):125-6.
Ma R 2010 {published data only}
  • Ma R, Cheng HL. [Guihong turtle shell pill for treating 68 cases of Qi and blood stagnation uterine myoma]. Henan Traditional Chinese Medicine 2010;30(4):382-3.
Ni XP 2012 {published data only}
  • Ni XP, Ma DZ, Lei LH. [Clinical observation of Xiaozheng decoction for 130 cases of uterine leiomyoma]. Journal of Traditional Chinese Medicine 2012;53(7):588-90, 594.
Wang XR 2011 {published data only}
  • Wang XR. [Clinical effect of GuizhiFuling capsule combined mifepristone in the treatment of uterine myoma]. Strait Pharmaceutical Journal 2011;23(10):127-9.
Wen Q 2005 {published data only}
  • Wen Q. [Therapeutic observation on effect of Tripterygium Wilfordii Hook and mifepristone in treatment of uterine leiomyoma]. Clinical Medicine of China 2005;21(3):277-9.
Wu JH 2011 {published data only}
  • Wu JH. [Analysis of clinical effect of Guizhi Fuling capsule combined mifepristone in the treatment of uterine myoma]. Maternal and Child Health Care of China 2011;26(19):2910-1.
Wu YF 2011 {published data only}
  • Wu YF, He L. Curative effect observation of mifepristone combined Guilin Fuling capsule treating uterine myoma. Progress in Modern Biomedicine 2010;3(17):49-50.
Yan LQ 2000 {published data only}
  • Yan LQ. [Clinical study on uterine fibroids treated by traditional Chinese medicine]. Journal of Changzhi Medical College 2000;14(4):304-5.
Zhu FH 2006 {published data only}
  • Zhu FH. [35 cases of hysteromyoma treated with mifepristone and Eleng Xiaozheng Decoction]. Fujian Journal of Traditional Chinese Medicine 2006;37(3):37.

References to studies excluded from this review

  1. References to studies included in this review
  2. References to studies excluded from this review
  3. Additional references
Akase 2003 {published data only}
  • Akase T, Onodera S, Jobo T, Matsushita R, Kaneko M, Tashiro S-I. [A comparative study of the usefulness of Toki-shakuyaku-san and an oral iron preparation in the treatment of hypochromic anaemia in cases of uterine myoma]. Yakugaku Zasshi 2003;123(9):817-24.
An ZR 2005 {published data only}
  • An ZR. [43 cases of uterine fibroids treated by Gong Liu Tang]. Modern Traditional Chinese Medicine 2005;25(6):30.
Chen QM 2007 {published data only}
  • Chen QM, Li FS, Wang JP. [Observation of therapeutic effects of Rupi Anxiao capsules plus small dosage of methyltestosterone in treatment of hysteromyoma]. Maternal and Child Health Care of China 2007;22(11):1459-61.
Cuan CL 2002 {published data only}
  • Cuan CL, Shang HQ, Fu YP. [30 cases of uterine fibroids treated by Ding Jing Tang]. Shaanxi Journal of Traditional Chinese Medicine 2002;23(11):975-6.
Du WH 1993 {published data only}
  • Du WH. [Retentive enema and oral taking of Guizhi Fuling Wan for treatment of 40 cases of uterine fibroids]. Shandong Journal of Traditional Chinese Medicine 1993;12(2):28-9.
Fang RD 2001 {published data only}
  • Fang RD, Zhang XH, Wang QY, Lin YZ, Yang SP, Rao WN, et al. [Clinical study on the treatment of uterine leiomyoma with Xiao Liu Yin iontophoresis]. Chinese Journal of Information on Traditional Chinese Medicine 2001;12(8):47-9.
Feng FQ 2003 {published data only}
  • Feng FQ. [Therapeutic effect of treating uterine fibroids with Guizhi Fuling capsules]. Modern Practical Medicine 2003;15(6):389.
Feng X 2004 {published data only}
  • Feng X. [Clinical observation of 39 cases of uterine fibroids treated by self-prescribed Ping Liu Tang]. Journal of Hebei Traditional Chinese Medicine and Pharmacology 2004;19(2):17.
Fu 2003 {published data only}
  • Fu J. Treatment of 48 cases of uterine fibroids by Yiqi Guchong and Huayu Sanjie therapy. Journal of Traditional Chinese Medicine 2003;44(9):706.
Fu P 2004 {published data only}
  • Fu P, He JL, Cui L, Chen XC. [Clinical observation on effect of Xuejie Hualiu Granule in treating hysteromyoma]. Chinese Archives of Traditional Chinese Medicine 2004;22(10):1082-4.
Gao SM 2006 {published data only}
  • Gao SM, Liu HY. [Clinical observation of 40 cases of hysteromyoma treated with therapy of nourishing Qi and activating blood circulation]. Journal of Practical Traditional Chinese Internal Medicine 2006;20(2):190-1.
Gao XL 2001 {published data only}
  • Gao XL, Zhang XR. [Clinical observation of 104 cases of hysteromyoma treated by Xiao Zheng No. 1]. Shanxi Journal of Traditional Chinese Medicine 2001;17(1):17-8.
Gao YP 2000 {published data only}
  • Gao YP, Chen DF. [Clinical study on effect of Tripterygium Wilfordii Hook on uterine leiomyoma]. Chinese Journal of Obstetrics and Gynaecology 2000;35(7):430-2.
Gu H 1992 {published data only}
  • Gu H. [Clinical summary of 35 cases of uterine fibroids treated with traditional Chinese medicine]. Jiangsu Journal of Traditional Chinese Medicine 1992;13(12):7-8.
Guo AQ 2000 {published data only}
  • Guo AQ, Guo YL, Wang XQ. [Clinical observation on treatment of 38 cases of climacteric myoma of uterus by combined traditional Chinese and western medicine]. Journal of Heze Medical College 2000;12(1):50-2.
Gu Y 2011 {published data only}
  • Gu Y. Effect of modified Sijunzi decoction combined Guizhi Fuling capsule treating uterine myoma. Journal of Practical Traditional Chinese Medicine 2011;27(12):838-9.
Han HL 1992 {published data only}
  • Han HL, Wang GF, Yang RX. [118 cases of uterine fibroids treated by Xiao Liu Wan]. Chinese Archives of Traditional Chinese Medicine 1992;10(1):36.
Han MX 2002 {published data only}
  • Han MX, Zhu ZS, Liu F. [32 cases of uterine fibroids treated by Qizhi Xiangfu Wan]. Shanxi Journal of Traditional Chinese Medicine 2002;18(1):21.
He H 2003 {published data only}
  • He H. [Treatment of 38 cases of hysteromyoma by Huangqi Danshen decoction]. Journal of Guangming Traditional Chinese Medicine 2003;18(109):36.
Huang XX 2011 {published data only}
Hu TX 2009 {published data only}
  • Hu TX, Shan XL, Shen SF. Comparison of curative effect of Gongliuqing capsule and radiofrequency catheter ablation in the treatment of uterine myoma. Journal of Clinical Medicine 2009;29(1):68-70.
Hu WD 2007 {published data only}
  • Hu WD. [Analysis on clinical efficacy of Shugan Xiaozheng decoction on hysteromyoma]. Modern Diagnosis and Treatment 2007;18(5):283, 320.
Hu WH 2009 {published data only}
  • Hu WH, Yang M. Clinical observation of Guizhi Fuling capsule treating 115 cases of uterine myoma. China Practical Medicine 2009;4(16):30-1.
Jiang JF 2002 {published data only}
  • Jiang JF. [Observation of therapeutic effects in 60 cases of hysteromyoma treated by Eleng Xiaoliu Tang]. Shandong Journal of Traditional Chinese Medicine 2002;21(4):215.
Jiang LG 2006 {published data only}
  • Jiang LG. [Clinical observation of 36 cases of hysteromyoma treated with Chinese herbal medicine compound]. Chinese Journal for Clinicians 2006;34(9):40-1.
Jiang P 2003 {published data only}
  • Jiang P, Zhao Y, Ruan YL, Han Y. [Clinical observation of 70 cases of hysteromyoma treated with integrated traditional Chinese and western medicine]. Modern Journal of Integrated Traditional Chinese and Western Medicine 2003;12(7):707-8.
Jiang XJ 2007 {published data only}
  • Jiang XJ, He FH. [Clinical analysis of mifepristone sequential treatment with Guizhi Fuling capsule on uterine myoma]. Zhejiang Journal of Clinical Medicine 2007;9(10):1338.
Jiang Y 2003 {published data only}
  • Jiang Y, Xie PS. [186 cases of uterine fibroids treated by traditional Chinese medicine]. Chinese Journal of Information on Traditional Chinese Medicine 2003;10(1):44.
Jiao JF 2011 {published data only}
  • Jiao JF. [Mifepristone combined Guilin Fuling capsule treated 39 cases of uterine myoma]. Chinese Journal of Experimental Traditional Medical Formulae 2011;17(12):292-3.
Jiao ML 2005 {published data only}
  • Jiao ML, Jiao XW. [Clinical observation of 53 cases of hysteromyoma treated by Gong Ji Ning pills]. Modern Traditional Chinese Medicine 2005;3(3):49.
Jia WH 2012 {published data only}
  • Jia WH. Treating 50 cases of uterine myoma with integrative medicine. Chinese Medicine Modern Distance Education of China 2012;10(2):58.
Ji CW 2004 {published data only}
  • Ji CW, Li QS, Pei ZY. [Clinical observation on treating hysteromyoma by Kunyaosan capsule]. Chinese Journal of Practical Integrated Chinese and Western Medicine 2004;4(1):117.
Kang YP 2005 {published data only}
  • Kang YP, Zheng SG. [46 cases of hysteromyoma at early stage treated with integrated traditional Chinese and western medicine]. Shaanxi Journal of Traditional Chinese Medicine 2005;26(5):402-3.
Lai HH 2004 {published data only}
  • Lai HH, Gao SF, Deng YM, Zhu ZH, Feng LP, Lai XF. [Clinical observation on Pugui Pill for treatment of 30 cases of hysteromyoma of stagnant heat type]. Journal of Traditional Chinese Medicine 2004;45(3):201-3.
Liang XZ 2011 {published data only}
  • Liang XZ, Zhang L. [Clinical research of Qizhuxiaozheng decoction treating uterine myoma]. Chinese Remedies & Clinics 2011;11(11):1309-10.
Liang YY 2006 {published data only}
  • Liang YY, Huang YH. [Ruanjian Sanjie granule for treatment of 42 cases of uterine fibroids]. Shaanxi Journal of Traditional Chinese Medicine 2006;27(6):677-8.
Li CY 2004 {published data only}
  • Li CY. [Clinical observation of Chinese herbal medicine plus ear acupoints pressing for the treatment of uterine fibroids with blood stasis]. Liaoning Journal of Traditional Chinese Medicine 2004;31(12):1015.
Li DM 1998 {published data only}
  • Li DM, Gao M, Li HM. [Observation of therapeutic effect of self-prescribed Xiao Zheng Yin for the treatment of hysteromyoma]. Chinese Journal of Traditional Medical Science and Technology 1998;5(2):85.
Li FY 1993 {published data only}
  • Li FY. [40 cases of uterine fibroids at early stage treated by Chinese herbal medicine]. New Journal of Traditional Chinese Medicine 1993;25(10):39-40.
Li JX 2005 {published data only}
  • Li JX. [Clinical observation of 125 cases of hysteromyoma with Qi-stagnancy and blood stasis treated with Zigong Xiaoliu tablets]. Practice on Chinese Clinical Medicines 2005;3(29):47-8.
Li JX 2006 {published data only}
  • Li JX, Zhang HZ. [Observation on therapeutic effects in hysteromyoma treated with integrated traditional Chinese and western medicine]. Journal of Changzhi Medical College 2006;20(4):300-1.
Li KY 2005 {published data only}
  • Li KY, Luo SP, Kuang ZS, Deng GP, Tao LL, Xie YH. [Effect of Lizhi Sanjie pill on levels of oestrogen and progestin of hysteromyoma patients]. Journal of Nanjing TCM University 2005;21(4):228-30.
Li LH 2010 {published data only}
  • Li LH. [Xiaoliutang decoction for treatment of 66 cases of uterine myoma]. Guangming Journal of Chinese Medicine. 2010;25(7):1228.
Li LZ 2003 {published data only}
  • Li LZ, Li GH, Chen P. [Clinical observation of Sanjie Xiaoliu Decoction for treatment of hysteromyoma]. Tianjin Journal of Traditional Chinese Medicine 2003;20(5):22-3.
Liu DX 2005 {published data only}
  • Liu DX, Luo X. [Clinical observation on the results in treatment of hyperplasia of mammary glands, hysteromyoma and oviduct blocking cases with Xiaoliu pills]. China Tropical Medicine 2005;5(8):1684-5.
Liu GY 2005 {published data only}
  • Liu GY. [Clinical observation on the treatment of 45 cases of uterine myoma with Zhechong Siwu decoction]. Guiding Journal of TCM 2005;11(2):33-4.
Liu JY 2002 {published data only}
  • Liu JY, Meng FL, Zhu L, Yu B, Liu YH, Nie FH. [Treatment of 64 cases of hysteromyoma in perimenopause women with integrated traditional Chinese and western medicine]. Chinese Journal of Integrated Traditional and Western Medicine 2002;22(4):248.
Liu QP 2001 {published data only}
  • Liu QP, He YN, Guo H. [Clinical observation of Guizhi Fuling Wan Jiawei for treatment of 37 cases of uterine fibroids]. Yunan Journal of Traditional Chinese Medicine and Materia Medica 2001;22(3):35-6.
Liu XF 2011 {published data only}
  • Liu XF. [Clinical observation on Chinese herbal medicine differentiation combined with western drug for treatment of uterine fibroids]. Liaoning Journal of Traditional Chinese Medicine 2011;38(6):1160-1.
Li WY 1999 {published data only}
  • Li WY, Yang GH, Jiang YH. [Clinical observation of Xiao Zheng Pill for treatment of hysteromyoma]. Hebei Journal of Traditional Chinese Medicine 1999;21(6):331-2.
Li WY 2002 {published data only}
  • Li WY. [Clinical study of treating hysteromyoma by Xiao Zheng Wan]. Chinese Journal of the Practical Chinese with Modern Medicine 2002;2(15):839-40.
Li Y 2003 {published data only}
  • Li Y, Qin SF, Wang LN. [Clinical observation of Danqi Huazheng capsule in the treatment of hysteromyoma]. Journal of Henan University of Chinese Medicine 2003;18(3):39-40.
Li YY 2002 {published data only}
  • Li YY. [Oral taking and external application of Chinese herbal medicine for treatment of 98 cases of uterine fibroids]. Hubei Journal of Traditional Chinese Medicine 2002;24(8):38-9.
Lu M 2007 {published data only}
  • Lu M. [Clinical observation of Yiqi Huayu Xiaozheng Tang for treatment of 60 cases of uterine fibroids]. Shandong Journal of Traditional Chinese Medicine 2007;26(9):604-6.
Luo L 2003 {published data only}
  • Luo L, Zhu YP. [Effect of treating 110 cases of uterine fibroids with the use of Qing Gong Liu capsules]. Chinese Journal of Traditional Medical Science and Technology 2003;10(6):382-3.
Lu SQ 2000 {published data only}
  • Lu SQ, Lin YC, Peng ZY. [Clinical observation of Xiaozheng Sanjie tablet in treating 120 cases of hysteromyoma]. Correspondence Journal of Traditional Chinese Medicine 2000;19(5):48-9.
Lu Y 2005 {published data only}
  • Lu Y, Deng ZH. [Clinical observation on the treatment of hysteromyoma with Qi-stagnancy and blood-stasis syndrome with Huazheng Decoction]. Journal of Anhui Traditional Chinese Medical College 2005;24(6):16-7.
Lv 2007 {published data only}
  • Lv M. [Clinical observation of 60 cases of hysteromyoma treated by Yiqi Huayu Xiaozheng Decoction]. Shandong Journal of Traditional Chinese Medicine 2007;26(9):604-6.
Man JP 2009 {published data only}
  • Man JP 2009. Huazhen Xiaoliu decoction treating 72 cases of uterine myoma. Chinese Medicine Modern Distance Education of China 2009;7(8):111.
Ma WX 2003 {published data only}
  • Ma WX, Li CP. [Xiao Liu Tang for treatment of 42 cases of uterine fibroids]. Traditional Chinese Medicine Research 2003;16(4):43-4.
Meng LJ 2010 {published data only}
  • Meng LJ, Li Y. [Efficacy analysis of Shuangju granules combined with mifepristone for treating uterine myoma]. Modern Chinese journal of integrated Chinese and Western Medicine 2010;19(20):2505-6.
Miao XL 2002 {published data only}
  • Miao XL. [Clinical curative observation of Xiao Liu granule for treatment of 130 cases of uterine fibroids]. Yunan Journal of Traditional Chinese Medicine and Materia Medica 2002;23(5):9-10.
Min XL 2007 {published data only}
  • Min XL. [Treatment of 42 cases of hysteromyoma by Xiao Liu formula]. Shaanxi Journal of Traditional Chinese Medicine 2007;28(3):298-9.
Miu XY 2003 {published data only}
  • Miu XY. [Treatment of 280 cases of hysteromyoma by Ji Liu San]. Fujian Journal of Traditional Chinese Medicine 2003;34(6):7-8.
Miu XY 2007 {published data only}
  • Miu XY. [Observation on therapeutic effect on Ji Liu San and Guizhi Fuling Tang for treatment of uterine fibroids]. Guangming Journal of Chinese Medicine 2007;22(2):31-3.
Mo KL 2011 {published data only}
  • Mo KL. [Application of Xiaojie'an combined with mifepristone in treatment of hysteromyoma in perimenopause period]. Chinese Journal of Clinical Rational Drug Use 2011;4(5C):57.
Pan XH 2011 {published data only}
  • Pan XH. [Mifepristone combined with Guizhi Fuling capsule for treating 39 cases of uterine myoma]. Journal of Practical Traditional Chinese Medicine 2011;27(12):851.
Peng XJ 2007 {published data only}
  • Peng XJ, Gao Y, Wang K. [Clinical Study on Huaji-Ye for treatment of uterine leiomyoma]. Shandong Journal of Traditional Chinese Medicine 2007;26(7):459-60.
Peng YS 2010 {published data only}
  • Peng YS, Qian X, Peng GJ. [Study on the theraputic effect of comprehensive treatment by Acupuncture with Chinese herbs on hysteromyoma]. China Medical Herald 2011;7(2):82-3.
Qian L 2007 {published data only}
  • Qian L, Qi C, Zhang QH. [Clinical observation of Bushen Xiaoliu recipe for 80 patients with myoma of uterus]. Journal of Practical Diagnosis and Therapy 2007;21(8):574-6.
Qi C 2003 {published data only}
  • Qi C, Qian B, Zhang QH, Huang ZH. [Clinical observation of 63 cases of hysteromyoma treated with herbal formula of nourishing kidney and activating blood circulation]. Journal of Sichuan of Traditional Chinese Medicine 2003;21(5):45-6.
Qin WP 2010 {published data only}
  • Qin WP, Peng LY, Niu YL, Zhang LJ. [Effective observation of herbal internal and external administration in the treatment of 122 cases of uterine myoma]. Hebei Journal of Traditional Chinese Medicine 2010;32(7):1005-6.
Qiu HN 2006 {published data only}
  • Qiu HN, Li FS. [Clinical observation of mifepristone combined with Guizhi Fuling capsules in perimenopause women with hysteromyoma]. Journal of Clinical Medicine in Practice 2006;10(3):103-4.
Sakamoto 1992 {published data only}
  • Sakamoto S, Yoshino H, Shirahata Y, Shimodairo K, Okamoto R. Pharmacotherapeutic effects of kuei-chih-fu-ling-wan (keishi-bukuryo-gan) on human uterine myomas. American Journal of Chinese Medicine 1992;20(3-4):313-7.
Sakamoto 1998 {published data only}
  • Sakamoto S, Mitamura T, Iwasawa M, Kitsunai H, Shindou K, Yagishita Y, et al. Conservative management for perimenopausal women with uterine leiomyomas using Chinese herbal medicines and synthetic analogs of gonadotropin-releasing hormone. In Vivo 1998;12(3):333-7.
Sang H 2004 {published data only}
  • Sang H, Wu B. [Clinical and experimental research into treatment of hysteromyoma with promoting Qi flow and blood circulation, softening and resolving hard lump]. Journal of Traditional Chinese Medicine 2004;24(4):274-9.
Sang HL 2002 {published data only}
  • Sang HL, Zhang QW, Jia SH. [Treatment of 150 cases of hysteromyoma with Kangfu Xiaozheng tablets]. Shandong Journal of Traditional Chinese Medicine 2002;21(3):143-4.
Sang HL 2003 {published data only}
  • Sang HL, Wu BQ. [Clinical and experimental study on Xingqi Huoxue and Ruanjian Sanjie therapy for treatment of uterine fibroids]. Journal of Traditional Chinese Medicine 2003;44(1):41-3.
Shen D 2006 {published data only}
  • Shen D, Shen XP. [Clinical observation on hysteromyoma treated by testosterone with or without Guizhi Fuling capsules]. Chinese Modern Medicine and Clinics 2006;1(5):12-3.
Shu S 2001 {published data only}
  • Shu S, Shu C. [Clinical observation of 30 cases of hysteromyoma treated with integrated traditional Chinese and western medicine]. Journal of Luoyang Medical College 2001;19(4):308-9.
Song JS 2010 {published data only}
  • Song JS, Gao C, Xiong J, Xue XH, Zhou YF, Shang TG. [Guizhi Fuling capsule versus western medicine for the treatment of uterine myoma: a systematic review. Chinese Journal of Evidence-Based Medicine 2010;10(12):1439-55.
Song SM 2006 {published data only}
  • Song SM, Hou YZ, Wang AF, Qian JY. [Clinical observation of 504 cases of hysteromyoma treated with Guizhi Fuling capsules]. Applied Journal of General Practice 2006;4(3):319.
Su GH 2005 {published data only}
  • Su GH. [Observation on therapeutic effect of Chinese medicine for treatment of uterine fibroids]. Shanxi Journal of Traditional Chinese Medicine 2005;21(6):60.
Sun DJ 2007 {published data only}
  • Sun DJ. [Observation on therapeutic effect of integrated Chinese and western medicine for treatment of 68 cases of uterine fibroids]. Asia-Pacific Traditional Medicine 2007;3(8):55.
Sun L 1995 {published data only}
  • Sun L. [38 cases of hysteromyoma treated with tumour-resolving decoction]. Journal of Traditional Chinese Medicine 1995;15(4):273-6.
Su XC 2005 {published data only}
  • Su XC, Wang YL, Zheng YS, Liu CL, Yan BC, Kong JX, et al. [Summary of 50 cases of uterine fibroids treated selectively by period with Zi Bao Kang capsule]. Hunan Journal of Traditional Chinese Medicine 2005;21(1):19-20.
Tan SY 2003 {published data only}
  • Tan SY. [Therapeutic observation of hysteromyoma treated with integrated traditional Chinese and western medicine]. Practical Clinical Journal of Integrated Traditional Chinese and Western Medicine 2003;3(3):11-2.
Tian LJ 2005 {published data only}
  • Tian LJ. [Clinical observation of Fu Liu Qing No. 1 for treatment of hysteromyoma in perimenopausal women]. Journal of Sichuan of Traditional Chinese Medicine 2005;23(6):69-70.
Tian Y 2011 {published data only}
  • Tian Y. [Clinical observation of mifepristone combined with Gongliuqing capsule in the treatment of uterine myoma]. Shandong Medical Journal 2011;51(1):53-4.
Wang D 2000 {published data only}
  • Wang D, Fan LX. [Treatment of 32 cases of myoma of uterus by Xiao Ji Pills]. Shaanxi Journal of Traditional Chinese Medicine 2000;21(5):199.
Wang DQ 2012 {published data only}
  • Wang DQ. [Effect of Guizhi Fuling capsule combined with mifepristone for treating 38 cases of uterine myoma]. Journal of Military Surgeon in Southwest China 2012;14(2):258.
Wang HM 2009 {published data only}
  • Wang HM, Liang RN, Luo XQ. [Clinical study on hysteromyoma treated with the method of huoxuehuayu after uterine artery embolization]. Modern Medicine Journal of China 2009;11(8):1-3.
Wang HZ 2010 {published data only}
  • Wang HZ, Chang H. [Clinical observation of Guizhi Fuling capsule combined with Danggui Shaoyao-San for treating 52 cases of uterine myoma]. Clinical Journal of Traditional Chinese Medicine 2010;22(4):322-3.
Wang JH 2002 {published data only}
  • Wang JH. [Chinese medicine for treatment of 67 cases of uterine fibroids]. Liaoning Journal of Traditional Chinese Medicine 2002;29(6):335.
Wang JH 2007 {published data only}
  • Wang JH. [Clinical study on Hua Zheng Dan for treatment of uterine leiomyoma]. Liaoning Journal of Traditional Chinese Medicine 2007;34(6):782-3.
Wang MD 1999 {published data only}
  • Wang MD. [Clinical observation of 112 cases of uterine leiomyoma treated by Tripterygium Wilfordii Hook]. Journal of Zhejiang University of Traditional Chinese Medicine 1999;23(6):29.
Wang P 2005 {published data only}
  • Wang P, Wang LM, Li L. [Therapeutic effect observation of 74 cases of uterine myoma treated by integration internal and external body]. Guiding Joumal of Traditional Chinese Medicine 2005;11(5):31-3.
Wang SL 2011 {published data only}
  • Wang SL. Self-prescribed Xiaoliu Capsule treated 50 cases of uterine myoma. Chinese Journal of Traditional Medical Science and Technology 2011;18(1):77.
Wang YH 2006 {published data only}
  • Wang YH, Han N. [Clinical observation of 40 cases of hysteromyoma treated by Huayu Xiaozheng decoction]. Chinese Journal of the Practical Chinese with Modern Medicine 2006;19(24):2947-9.
Wang YL 2004 {published data only}
  • Wang YL. [Clinical observation of 64 cases of hysteromyoma in perimenopause women treated with integrated traditional Chinese and western medicine]. Jilin Journal of Traditional Chinese Medicine 2004;25(1):38-9.
Weng SQ 2010 {published data only}
  • Weng SQ, Huang LH, Wang XY, Xia AJ, Li QL. [Clinical observation of Ankun tablet treating 50 cases of uterine myoma]. Information on Traditional Chinese Medicine 2010;27(3):96-8.
Wen XL 2007 {published data only}
  • Wen XL. [Xiao Liu Fang for treatment of 42 cases of uterine fibroids]. Shaanxi Journal of Traditional Chinese Medicine 2007;28(3):298-9.
Wu N 2002 {published data only}
  • Wu N. [Clinical observation on treatment of 55 cases of hysteromyoma by reinforcing kidney and regulating menstrual cycle]. Jiangsu Journal of Traditional Chinese Medicine 2002;23(6):21-2.
Wu XM 2007 {published data only}
  • Wu XM, Liu F, Liu QZ. [Observation of hysteromyoma treated by combination of traditional Chinese medicine and western medicine]. Hei Long Jiang Medical Journal 2007;31(8):610-1.
Xiao CC 1990 {published data only}
  • Xiao CC, Yang BY, Huangpu X, Guo Y, Zhang SM. [Clinical observation on Jiliu Neixiao Wan for treatment of 125 cases of uterine fibroids]. China Journal of Traditional Chinese Medicine and Pharmacy 1990;5(2):39-41.
Xiong DM 2006 {published data only}
  • Xiong DM, Zhang XL. [Clinical therapeutic observation of 68 cases of hysteromyoma treated with integrated traditional Chinese and western medicine]. Shenzhen Journal of Integrated Traditional Chinese and Western Medicine 2006;16(1):38-40.
  • Xiong DM, Zhao L, Zhang XL. [Treatment of 38 cases of uterine fibroids by Guizhi Fuling capsules]. Shaanxi Journal of Traditional Chinese Medicine 2006;27(6):679-80.
Xu H 2005 {published data only}
  • Xu H, Xu ZX. [Xiao Zheng Tang for treatment of 38 cases of uterine fibroids]. Liaoning Journal of Traditional Chinese Medicine 2005;32(10):1045.
Xu Y 2007 {published data only}
  • Xu Y. [Effect observation of integrated Chinese and western medicine for treatment of uterine fibroids]. Clinical Misdiagnosis and Mistherapy 2007;20(7):60-1.
Yang JL 2001 {published data only}
  • Yang JL, Yan XP. [Clinical observation of 300 cases of hysteromyoma treated with Gong Liu Qing capsule]. Journal of Chengdu University of Traditional Chinese Medicine 2001;24(1):10-3.
Yang YX 2005 {published data only}
  • Yang YX, Huang BZ, Wang MJ, Li RR. [Clinical observation of 148 cases of hysteromyoma treated with integrated traditional Chinese and western medicine]. Modern Journal of Integrated Traditional Chinese and Western Medicine 2005;14(24):3233-4.
Yang ZM 2011 {published data only}
Yan H 1994 {published data only}
  • Yan H, Wang J. [Clinical study on acupuncture for treatment of hysteromyoma]. Acupuncture Research 1994;19(2):14-6.
Yan Y 2001 {published data only}
  • Yan Y. [Clinical observation of Guizhi Fuling capsules combined with mifepristone for the treatment of uterine fibroids]. Acta Academiae Medicinae Xuzhou 2001;21(5):428-9.
Ye JF 2001 {published data only}
  • Ye JF, Wang YX. [Ingredient added "Tumor-Reducing Prescription" for hysteromyoma in 45 cases]. Shanghai Journal of Traditional Chinese Medicine 2001;35(2):33-4.
Ye TH 2002 {published data only}
  • Ye TH. [Clinical observation of 60 cases of hysteromyoma treated with Gong Liu Xiao capsule]. Journal of Sichuan of Traditional Chinese Medicine 2002;20(1):53-4.
Yu JY 2004 {published data only}
  • Yu JY. [Xiao Liu Wan for treatment of 60 cases of uterine fibroids]. Nei Mongol Journal of Traditional Chinese Medicine 2004;23(4):9.
Yu QL 2003 {published data only}
  • Yu QL. [Clinical observation of 30 cases of hysteromyoma treated by Wanying Xiaoliu San]. Chinese Journal of Current Clinical Medicine 2003;1(8):724-5.
Yu T 2002 {published data only}
  • Yu T, Cao SW, Zhi N. [Clinical observation of 30 cases of hysteromyoma treated by Huashi Sanjie Decoction]. Jiangxi Journal of Traditional Chinese Medicine 2002;33(5):23-4.
Zhang H 2005 {published data only}
  • Zhang H. [Chinese herbal medicine combined with transcatheter arterial embolization for treatment of 21 cases of uterine fibroids]. Shandong Journal of Traditional Chinese Medicine 2005;24(12):725-6.
Zhang M 2004 {published data only}
  • Zhang M. [Use of worms for treatment of uterine fibroids]. Liaoning Journal of Traditional Chinese Medicine 2004;31(1):61.
Zhang QM 2007 {published data only}
  • Zhang QM, Chen X, Sun ZY, Yuan JL. [Clinical observation on curative effect of Yuan Xiao Liu decoction for treatment of hysteromyoma]. Liaoning Journal of Traditional Chinese Medicine 2007;34(9):1272-3.
Zhang WH 2011 {published data only}
  • Zhang WH. [Clinical observation of Guizhi Fuling capsule treating 34 cases of uterine myoma]. Seeking Medicine and Asking Drug 2011;9(10):202.
Zhang WL 2005 {published data only}
  • Zhang WL, Shen J. [Clinical observation of mifepristone alone or in combination of Chinese medicine for treatment of uterine fibroids]. Chinese Journal of Clinical Medicine Research 2005;11(17):2463-4.
Zhang XB 2011 {published data only}
  • Zhang BX, Yang JH, Liu YL. [Clinical observation of interventional embolization combined with Xiaozheng Tang for treating uterine myoma]. Medical Information 2011;9(9):4542-3.
Zhang XW 1997 {published data only}
  • Zhang XW, Hao SZ. [The clinical analysis of thirty-eight cases of hysteromyoma treated with Hai Kun decoction]. Chinese Journal of Marine Drugs 1997;16(2):43-5.
Zhang Z 2006 {published data only}
  • Zhang Z. [Jiawei Guizhi Fuling Wan for treatment of 62 cases of uterine fibroids]. Journal of Sichuan of Traditional Chinese Medicine 2006;24(1):88.
Zhan YR 2007 {published data only}
  • Zhan YR. [Analysis of mifepristone and Guizhi Fuling capsule for treatment of uterine fibroids]. International Medicine and Health Guidance News 2007;13(2):63-5.
Zhao LX 2003 {published data only}
  • Zhao LX. [Treatment of 64 cases of uterine fibroids by Tripterygium Wilfordii Hook]. Chinese Journal of Integrated Traditional and Western Medicine 2003;23(10):787-8.
Zheng CY 2003 {published data only}
  • Zheng CY, Zhong QL. [Dahuang Zhechong Wan Jiawei for treatment of 60 cases of uterine fibroids]. Guangxi Journal of Traditional Chinese Medicine 2003;26(5):33.
Zhong Q 2006 {published data only}
  • Zhong Q, Fen JY, Liang SX, Xu YJ. [Clinical observation of hysteromyoma in perimenopause women by conservative treatment of integrated traditional Chinese and western medicine]. Chinese Journal of Clinical Medicine Research 2006;12(7):964-5.
Zhong XR 2010 {published data only}
  • Zhong XR, Lin F, Tang GC. [Clinical observation of mifepristone combined with Gongliuqing capsule in the treatment of uterine myoma]. Practical Clinical Journal of Integrated Traditional Chinese and Western Medicine 2010;10(5):41, 43.
Zhou J 1997 {published data only}
  • Zhou J, Zhu M, Li YX, Shi JR, Yuan MF, Shen ZL, et al. [Clinical and experimental study on improving cellular immunological function of uterine myoma patients by Xiaoliu tablet]. Zhongguo Zhong Xi Yi Jie He Za Zhi 1997;17(5):277-9.
Zhou MY 2003 {published data only}
  • Zhou MY, Wang JJ, Cao LP, Chen CL, Liu P. [Observation on therapeutic effect of Da Huang Tang combined with uterine artery embolization for treatment of uterine fibroids]. Liaoning Journal of Traditional Chinese Medicine 2003;30(7):561-2.
Zhou YJ 2006 {published data only}
  • Zhou YJ, Gao J. [Treatment of 30 cases of hysteromyoma with Guizhi Fuling capsules]. China Journal of Clinical Medicine Hygiene 2006;4(10):66-7.
Zhou YR 1999 {published data only}
  • Zhou YR, Sun FL, Wang CX. [Clinical observation of 48 cases of hysteromyoma treated with Bushen, Poyu and Huatan recipe]. Chinese Journal of Primary Medicine and Pharmacy 1999;6(5):282.
Zhu JY 1997 {published data only}
  • Zhu JY, Chen M, Zhuang CS, Luo ZH. [Treatment of 80 cases of hysteromyoma with LIzhong Sanjie pills]. New Journal of Traditional Chinese Medicine 1997;29(1):34.
Zou DH 1993 {published data only}
  • Zou DH. [Clinical observation on practitioner Gong Zi Fu's differentiation of syndrome for treatment of 93 cases of uterine fibroids]. Jiangxi Journal of Traditional Chinese Medicine 1993;24(6):13-4.

Additional references

  1. References to studies included in this review
  2. References to studies excluded from this review
  3. Additional references
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Gupta 2012
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Kjaergard 2001
Klatsky 2008
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Lethaby 2001
Li J 2008
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Marshall 1997
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Maruo 2004
McLucas 2001
Moher 1998
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Okolo 2008
Sang 2004
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Schulz 1995
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Stewart 2001
Tranquart 2002
Tristan 2012
Vickers 1998
Watson 2002
Xiong 2002
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Yuan 2000
Zimmermann 2012
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