Intervention Review

Physical activity and enhanced fitness to improve cognitive function in older people without known cognitive impairment

  1. Maaike Angevaren1,*,
  2. Geert Aufdemkampe2,
  3. HJJ Verhaar3,
  4. A Aleman4,
  5. Luc Vanhees1

Editorial Group: Cochrane Dementia and Cognitive Improvement Group

Published Online: 16 JUL 2008

Assessed as up-to-date: 31 JAN 2008

DOI: 10.1002/14651858.CD005381.pub3

How to Cite

Angevaren M, Aufdemkampe G, Verhaar HJJ, Aleman A, Vanhees L. Physical activity and enhanced fitness to improve cognitive function in older people without known cognitive impairment. Cochrane Database of Systematic Reviews 2008, Issue 3. Art. No.: CD005381. DOI: 10.1002/14651858.CD005381.pub3.

Author Information

  1. 1

    University of Applied Sciences, Research Group Lifestyle and Health, Utrecht, Netherlands

  2. 2

    University of Professional Education, Research Department of Health and Lifestyle, Utrecht, Netherlands

  3. 3

    University Medical Centre Utrecht, Department of Geriatric Medicine, Utrecht, Netherlands

  4. 4

    B C Neuro Imaging Centre, Groningen, Netherlands

*Maaike Angevaren, Research Group Lifestyle and Health, University of Applied Sciences, Bolognalaan 101, Utrecht, 3584 CJ, Netherlands.

Publication History

  1. Publication Status: New search for studies and content updated (conclusions changed)
  2. Published Online: 16 JUL 2008


Cited in:


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  2. 2
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  3. 3
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  4. 4
    M. Émile, A. Chalabaev, C. Pradier, C. Clément-Guillotin, C. Falzon, S.S. Colson, F. d’Arripe-Longueville, Effects of supervised and individualized weekly walking on exercise stereotypes and quality of life in older sedentary females, Science & Sports, 2014, 29, 3, 156


  5. 5
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  6. 6
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  7. 7
    Michelle E. Kelly, David Loughrey, Brian A. Lawlor, Ian H. Robertson, Cathal Walsh, Sabina Brennan, The impact of exercise on the cognitive functioning of healthy older adults: A systematic review and meta-analysis, Ageing Research Reviews, 2014, 16, 12


  8. 8
    Ashley J. Lamont, Moyra E. Mortby, Kaarin J. Anstey, Perminder S. Sachdev, Nicolas Cherbuin, Using sulcal and gyral measures of brain structure to investigate benefits of an active lifestyle, NeuroImage, 2014, 91, 353


  9. 9
    Bernd Rechel, Emily Grundy, Jean-Marie Robine, Jonathan Cylus, Johan P Mackenbach, Cecile Knai, Martin McKee, Ageing in the European Union, The Lancet, 2013, 381, 9874, 1312


  10. 10
    Giselle M Petzinger, Beth E Fisher, Sarah McEwen, Jeff A Beeler, John P Walsh, Michael W Jakowec, Exercise-enhanced neuroplasticity targeting motor and cognitive circuitry in Parkinson's disease, The Lancet Neurology, 2013, 12, 7, 716


  11. 11
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  12. 12
    Ansgar Felbecker, Barbara Tettenborn, Carl D. Reimers, Guido Knapp, Prävention und Therapie neurologischer und psychischer Krankheiten durch Sport, 2013,


  13. 13
    Yaakov Stern, Cognitive reserve in ageing and Alzheimer's disease, The Lancet Neurology, 2012, 11, 11, 1006


  14. 14
    Sara Gregory, Beth Parker, Paul Thompson, Physical Activity, Cognitive Function, and Brain Health: What Is the Role of Exercise Training in the Prevention of Dementia?, Brain Sciences, 2012, 2, 4, 684


  15. 15
    Deborah E Barnes, Kristine Yaffe, The projected effect of risk factor reduction on Alzheimer's disease prevalence, The Lancet Neurology, 2011, 10, 9, 819


  16. 16
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  17. 17
    Dorothy Forbes, Emily J Thiessen, Catherine M Blake, Scott C Forbes, Sean Forbes, Exercise programs for people with dementia, The Cochrane Library,
  18. 18
    Dorothy Forbes, Sean Forbes, Debra G Morgan, Maureen Markle-Reid, Jennifer Wood, Ivan Culum, Physical activity programs for persons with dementia, The Cochrane Library,
  19. 19
    Grainne S. Gorman, Josh Wood, Michael I. Trenell, Physical Activity, Exercise, and Aging, Wellbeing,