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Intervention Review

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Oral zinc for treating diarrhoea in children

  1. Marzia Lazzerini1,*,
  2. Luca Ronfani2

Editorial Group: Cochrane Infectious Diseases Group

Published Online: 31 JAN 2013

Assessed as up-to-date: 20 FEB 2012

DOI: 10.1002/14651858.CD005436.pub4


How to Cite

Lazzerini M, Ronfani L. Oral zinc for treating diarrhoea in children. Cochrane Database of Systematic Reviews 2013, Issue 1. Art. No.: CD005436. DOI: 10.1002/14651858.CD005436.pub4.

Author Information

  1. 1

    WHO Collaborating Centre for Maternal and Child Health, Institute for Maternal and Child Health, Unit for Health Services Research and International Health, Trieste, Italy

  2. 2

    Institute for Maternal and Child Health, Unit of Epidemiology and Biostatistics, Trieste, Italy

*Marzia Lazzerini, Unit for Health Services Research and International Health, WHO Collaborating Centre for Maternal and Child Health, Institute for Maternal and Child Health, IRCCS Burlo Garofolo, Trieste, 8232, Italy. lazzerini@burlo.trieste.it.

Publication History

  1. Publication Status: Edited (no change to conclusions)
  2. Published Online: 31 JAN 2013

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This is not the most recent version of the article. View current version (20 DEC 2016)

[Figure 1]
Figure 1. Methodological quality graph: review authors' judgements about each methodological quality item presented as percentages across all included studies.
[Figure 2]
Figure 2. Methodological quality summary: review authors' judgements about each methodological quality item for each included study.
[Figure 3]
Figure 3. Zinc vs placebo for acute diarrhoea: diarrhoea duration (h)
[Figure 4]
Figure 4. Zinc vs placebo for acute diarrhoea: diarrhoea on day 3
[Figure 5]
Figure 5. Zinc vs placebo for acute diarrhoea: diarrhoea on day 5
[Figure 6]
Figure 6. Zinc vs placebo for acute diarrhoea: diarrhoea on day 7
[Figure 7]
Figure 7. Zinc vs placebo for acute diarrhoea: Adverse events (vomiting)
[Figure 8]
Figure 8. Forest plot of comparison: 2 Zinc vs placebo for mean acute diarrhoea duration: subgroup analysis excluding children < 6 months, outcome: 2.1 Diarrhoea duration (h).
[Figure 9]
Figure 9. Forest plot of comparison: 3 Zinc vs placebo for acute diarrhoea on day 7: subgroup analysis excluding children < 6 months, outcome: 3.1 Diarrhoea on day 7.
[Figure 10]
Figure 10. Zinc vs placebo for persistent diarrhoea: diarrhoea duration (h)
[Analysis 1.1]
Analysis 1.1. Comparison 1 Zinc vs placebo for acute diarrhoea, Outcome 1 Diarrhoea duration (h).
[Analysis 1.2]
Analysis 1.2. Comparison 1 Zinc vs placebo for acute diarrhoea, Outcome 2 Diarrhoea on day 3.
[Analysis 1.3]
Analysis 1.3. Comparison 1 Zinc vs placebo for acute diarrhoea, Outcome 3 Diarrhoea on day 5.
[Analysis 1.4]
Analysis 1.4. Comparison 1 Zinc vs placebo for acute diarrhoea, Outcome 4 Diarrhoea on day 7.
[Analysis 1.5]
Analysis 1.5. Comparison 1 Zinc vs placebo for acute diarrhoea, Outcome 5 Stool frequency (stools /day).
[Analysis 1.6]
Analysis 1.6. Comparison 1 Zinc vs placebo for acute diarrhoea, Outcome 6 Adverse events (vomiting).
[Analysis 2.1]
Analysis 2.1. Comparison 2 Zinc vs placebo for mean acute diarrhoea duration: subgroup analysis excluding children < 6 months, Outcome 1 Diarrhoea duration (h).
[Analysis 3.1]
Analysis 3.1. Comparison 3 Zinc vs placebo for acute diarrhoea on day 7: subgroup analysis excluding children < 6 months, Outcome 1 Diarrhoea on day 7.
[Analysis 4.1]
Analysis 4.1. Comparison 4 Zinc vs placebo for persistent diarrhoea, Outcome 1 Diarrhoea duration (h).
[Analysis 4.2]
Analysis 4.2. Comparison 4 Zinc vs placebo for persistent diarrhoea, Outcome 2 Diarrhoea on day 3.
[Analysis 4.3]
Analysis 4.3. Comparison 4 Zinc vs placebo for persistent diarrhoea, Outcome 3 Diarrhoea on day 5.
[Analysis 4.4]
Analysis 4.4. Comparison 4 Zinc vs placebo for persistent diarrhoea, Outcome 4 Diarrhoea on day 7.
[Analysis 4.5]
Analysis 4.5. Comparison 4 Zinc vs placebo for persistent diarrhoea, Outcome 5 Stool frequency (stools/day).
[Analysis 4.6]
Analysis 4.6. Comparison 4 Zinc vs placebo for persistent diarrhoea, Outcome 6 Adverse events (vomiting).