Intervention Review

You have full text access to this OnlineOpen article

Corticosteroids for preventing postherpetic neuralgia

  1. Ying Han1,*,
  2. Jingjing Zhang2,
  3. Ning Chen2,
  4. Li He2,
  5. Muke Zhou2,
  6. Cairong Zhu3

Editorial Group: Cochrane Neuromuscular Disease Group

Published Online: 28 MAR 2013

Assessed as up-to-date: 16 APR 2012

DOI: 10.1002/14651858.CD005582.pub4

How to Cite

Han Y, Zhang J, Chen N, He L, Zhou M, Zhu C. Corticosteroids for preventing postherpetic neuralgia. Cochrane Database of Systematic Reviews 2013, Issue 3. Art. No.: CD005582. DOI: 10.1002/14651858.CD005582.pub4.

Author Information

  1. 1

    Xuanwu Hospital, Capital Medical University, Department of Neurology, Beijing, China

  2. 2

    West China Hospital, Sichuan University, Department of Neurology, Chengdu, Sichuan, China

  3. 3

    School of Public Health, Sichuan University, Epidemic Disease & Health Statistics Department, Sichuan, Chengdu, China

*Ying Han, Department of Neurology, Xuanwu Hospital, Capital Medical University, No. 45, Changchun Street, Xicheng District, Beijing, 100053, China. sophiehanying@gmail.com.

Publication History

  1. Publication Status: New search for studies and content updated (no change to conclusions)
  2. Published Online: 28 MAR 2013

SEARCH

References

References to studies included in this review

  1. References to studies included in this review
  2. References to studies excluded from this review
  3. References to studies awaiting assessment
  4. Additional references
  5. References to other published versions of this review
Clemmensen 1984 {published data only}
Eaglstein 1970 {published data only}
  • Eaglstein WH, Katz R, Brown JA. The effects of early corticosteroid therapy on the skin eruption and pain of herpes zoster. JAMA 1970;211(10):1681-3. [PUBMED: 4905733]
Esmann 1987 {published data only}
  • Esmann V, Geil JP, Kroon S, Fogh H, Peterslund NA, Petersen CS, et al. Prednisolone does not prevent post-herpetic neuralgia. Lancet 1987;2(8551):126-9. [PUBMED: 2885599]
Whitley 1996 {published data only}
  • Whitley RJ, Weiss H, Gnann JW Jr, Tyring S, Mertz GJ, Pappas PG, et al. Acyclovir with and without prednisone for the treatment of herpes zoster: a randomized, placebo-controlled trial. Annals of Internal Medicine 1996;125(5):376-83. [PUBMED: 8702088]
Wood 1994a {published data only}
  • Wood MJ, Johnson RW, Mckendrick MW, Taylor J, Mandal BK, Crooks J. A randomized trial of acyclovir for 7 days or 21 days with and without prednisolone for treatment of acute herpes zoster. New England Journal of Medicine 1994;330(13):896-900. [PUBMED: 8114860]

References to studies excluded from this review

  1. References to studies included in this review
  2. References to studies excluded from this review
  3. References to studies awaiting assessment
  4. Additional references
  5. References to other published versions of this review
Benoldi 1991 {published data only}
Brusco 1993 {published data only}
  • Brusco JE, JaimovichCB, Bacchiocchi MF. Herpes zoster, study of 96 patients: postherpetic neuralgia and corticoids [Herpes zoster, estudio de 96 pacientes: neuralgia postherpética y corticoides]. Archivos Argentinos de Dermatología 1993;43(3):175-83.
Chang 2004 {published data only}
  • Chang JF. Corticosteroids for the treatment of postherpetic neuralgia. Chinese Journal of Practical Medicine 2004;4(9):830.
Cui 2002 {published data only}
  • Cui SS, Cheng XH. Evaluation of the effect of corticosteroids for the prevention of PHN in the elderly people. Journal of DaLian Medical University 2002;24(2):116-7.
Guo 2001 {published data only}
  • Guo QJ. Corticosteroids plus combined therapy for the treatment of 57 cases with herpes zoster. ShanDong Medical Journal 2001;41(1):53.
Hao 2002 {published data only}
  • Hao SZ. Clinical efficacy of acyclovir combined with prednisone for the treatment of 48 cases with herpes zoster in aged persons. Journal of JinZhou Medical College 2002;23(5):57.
Huang 2004 {published data only}
  • Huang YZ. Clincial efficacy of acyclovir combined prednisone given by intravenous routes for the treatment of herpes zoster in middle-aged persons. International Medical & Heath Guidance News 2004;10(2-3):81-2.
Huang 2010 {published data only}
  • Huang ZF, Huang YZ, Ma DX. Combined treatment of famciclovir and compound betamethasone for herpes zoster in middle-aged and aged population [泛昔洛韦联合复方倍他米松注射液治疗中老年带状疱疹疗效观察]. Guangdong Medical Journal 2010;31(13):1746-7.
Jiang 2005 {published data only}
  • Jiang MB, Jiang JY, Wang SJ. Clinical efficacy of ribaviron combined with dexamethasone for the treatment of 38 cases with herpes zoster in middle-aged persons. Theory and Practice of Chinese Medicine 2005;15(2):163.
Jiang 2008 {published data only}
  • Jiang CH. [Short-term combined treatment with small dose of corticosteroids and acyclovir for herpes zoster]. China Journal of Leprosy and Skin Disease 2008;4:255.
Keczkes 1980 {published data only}
Li 2000 {published data only}
  • Li YF. Clinical observation of acyclovir combined with prednisone for the treatment of herpes zoster. Journal of Zhejiang Medicine. Science 2000;22(7):441-2.
Li 2002 {published data only}
  • Li QH, Shi X, Li B. Clinical efficacy of acyclovir combined with prednisone for the treatment of herpes zoster in middle-aged persons. The Chinese Journal of Dermatovenereology 2002;16(3):2.
Liao 2005 {published data only}
  • Liao JY, Yan ZQ, Liu GT. Acyclovir plus prednisone was applied to the treatment of senile herpes zoster. Clinical Journal of Military Surgeon 2005;33(4):413-4.
Lin 2002 {published data only}
  • Lin LZ. A combination oral therapy with prednisone and acyclovir in treatment of 34 cases with herpes zoster. Journal of Clinical Dermatology 2002;31(1):30-1.
Lin 2005 {published data only}
  • Lin BS. Clinical efficacy of valacyclovir combined with low dosage of prednisone for the treatment of herpes zoster in aged persons. Southern China Journal of Dermato-Venereology 2005;12(1):21-2.
Liu 2003 {published data only}
  • Liu Y, Dun SH. Aciclovir combined with prednisone for the treatment of herpes zoster neuralgia in aged persons. Chinese Journal of Clinical Rehabilitation 2003;7(11):1727.
Liu 2005 {published data only}
  • Liu YB. Clinical observation of acyclovir combined with prednisone for the treatment of herpes zoster neuralgia in middle-aged persons. Journal of LiaoNing College of Traditional Chinese Medicine 2005;7(3):251.
Ma 2000 {published data only}
  • Ma WY. Clincial observation of antiviral agents combined with dexamethasone for the treatment of herpes zoster. QingHai Medical Journal 2000;30(10):44.
Ma 2002 {published data only}
  • Ma J, Cai AH, Cao MR. Glucocorticoid alleviates postherpetic neuralgia. Journal of China Clinical Medicine 2002;9(5):578-9.
Shi 2008 {published data only}
  • Shi RY, Liu FZ. Acyclovir combined with prednisone for 24 patients with herpes zoster. Chinese Coummunity Doctors 2008;12:37.
Song 2009 {published data only}
  • Song KT. Combined treatment with interferon, acyclovir and steroid for patients with herpes zoster. Chinese Journal of Misdiagnosis 2009;9(6):1344-5.
Tang 2004 {published data only}
  • Tang JC. Andrographolide combined with prednisone for the treatment of herpes zoster in middle-aged persons. JiLin Journal of Traditional Chinese Medicine 2004;24(6):34.
Wang 2004 {published data only}
  • Wang HQ. Clinical observation of valaciclovir combined with prednisone for the treatment of herpes zoster in middle-aged persons. Chinese of Celiopathy 2004;4(5):344-5.
Xu 1999 {published data only}
  • Xu YC. Clinical observation of acyclovir combined with prednisone for the treatment of herpes zoster. Journal of Clinical Dermatology 1999;28(3):181.
Yang 2000 {published data only}
  • Yang J, Huang XY, Hou J. Control study of prednisone in prevention of senile postherpetic neuralgia. Journal of Clincial Dermatology 2000;29(2):99-100.
Yang 2002 {published data only}
  • Yang JL, Hu YY. Clinical observation of acyclovir combined with prednisone for the treatment of herpes zoster. Practical Clinical Medicine 2002;3(6):128.
Yang 2010 {published data only}
  • Yang XM. [Acyclovir combined with prednisone for herpes zoster]. Chinese Journal of Clinical Rational Drug Use 2010;3(6):31.
Yin 2004 {published data only}
  • Ying GW, He QB, Li DQ, Yu JB. Clinical Observation of low dosage of corticosteroids for the prevention of PHN in elderly people. Chinese Journal of Geriatrics 2004;23(8):579.
Yin 2005 {published data only}
  • Yin GW, He QB, Li DQ, Yu JB. The observation of efficacy and safety of glucocorticoids for the treatment of herpes zoster. Chinese Journal of Practitioner 2005;4(3):187.
Zeng 2011 {published data only}
  • Zeng C. Corticosteroids for the treatment of postherpetic neuralgia [糖皮质激素治疗带状疱诊对防治后遗神经痛的疗效观察]. Zhong Guo Jian Kang Yue Kan (China Health Monthly) 2011;30(5):49-50.
Zhang 2003 {published data only}
  • Zhang JM. A clinical comprehend of Virmax combined prednisone in the treatment of 30 cases with herpes zoster in aged persons. Journal of HanDan Medical College 2003;16(2):115.
Zhang 2004 {published data only}
  • Zhang CM, Wang FF, Zhu YM, Ren Y. Control study of prednisone in prevention of senile postherpetic neuralgia. Journal of ChengDe Medical College 2004;21(3):199-200.
Zhang 2005 {published data only}
  • Zhang JQ. Acyclovir combined with low dosage prednisone for the treatment of 30 cases with herpes zoster. Clinical Journal of Integrated Traditional and Western Medicine 2005;5(3):44.
Zheng 2004 {published data only}
  • Zheng HY, Han J. Clinical study of early combination treatment for patients with herpes zoster. Journal of Jingangshan Medical College 2004;11(3):66.
Zhou 2000 {published data only}
  • Zhou XY. Famciclovir combined with prednisone for the treatment of herpes zoster in aged persons. Journal of BaiQiuEn Medical College 2000;26(6):647.
Zhou 2008 {published data only}
  • Zhou J. [Clinical effect investigation of herpes zoster with glucocorticosteroids and acyclovir in old patients]. Journal of North Sichuan Medical College 2008;23(3):255-6.

References to studies awaiting assessment

  1. References to studies included in this review
  2. References to studies excluded from this review
  3. References to studies awaiting assessment
  4. Additional references
  5. References to other published versions of this review
Hu 2001 {published data only}
  • Hu XY. Acyclovir combined with dexamethasone for the treatment of 45 cases with herpes zoster. World Journal of Infection 2001;1:5-6.

Additional references

  1. References to studies included in this review
  2. References to studies excluded from this review
  3. References to studies awaiting assessment
  4. Additional references
  5. References to other published versions of this review
Alper 2002
de Moragas 1957
  • de Moragas JM, Kierland RR. The outcome of patients with herpes zoster. A.M.A. Archives of Dermatology 1957;75(2):193-6.
Desmond 2002
  • Desmond RA, Weiss HL, Arani RB, Soong SJ, Wood MJ, Fiddian PA, et al. Clinical applications for change-point analysis of herpes zoster pain. Journal of Pain and Symptom Management 2002;23(6):510-6.
Dworkin 1994
Dworkin 2000
  • Dworkin RH, Perkins FM, Nagasako EM. Prospects for the prevention of postherpetic neuralgia in herpes zoster patients. The Clinical Journal of Pain 2000;16(2 Suppl):S90-100.
Dworkin 2007
Fillet 2002
GRADE working group 2004
  • GRADE Working Group. Grading quality of evidence and strength of recommendations. BMJ 2004;328:1490-4.
Griffin 1998
Higgins 2002
Higgins 2003
Higgins 2011
  • Julian PT Higgins, Douglas G Altman, Jonathan AC Sterne (editors). Chapter 8: Assessing risk of bias in included studies. In: Higgins JPT, Green S editor(s). Cochrane Handbook for Systematic Reviews of Intervention Version 5.1.0 ( updated March 2011). The Cochrane Collaboration, 2011.
Johnson 2003
Kost 1996
  • Kost RG, Straus SE. Postherpetic neuralgia - pathogenesis, treatment, and prevention. The New England Journal of Medicine 1996;335(1):32-42.
Lancaster 1995
  • Lancaster T, Silagy C, Gray S. Primary care management of acute herpes zoster: systematic review of evidence from randomized controlled trials. British Journal of General Practice 1995;45(390):39-45.
Levinson 1985
Li 2009
MacDonald 2000
  • MacDonald BK, Cockerell OC, Sander JW, Shorvon SD. The incidence and lifetime prevalence of neurological disorders in a prospective community-based study in the UK. Brain 2000;123(Pt 4):665-76.
Mahalingam 1993
  • Mahalingam R, Wellish M, Lederer D, Forghani B, Cohrs R, Gilden DH. Quantitation of latent varicella-zoster virus DNA in human trigeminal ganglia by polymerase chain reaction. Journal of Virology 1993;67(4):2381-4.
Rosler 1996
Schünemann 2011
  • Schünemann HJ, Oxman AD, Higgins JPT, Vist GE, Glasziou P, et al. Chapter 11: Presenting results and ‘Summary of findings' tables. In: Higgins JPT, Green S (editors), Cochrane Handbook for Systematic Reviews of Interventions Version 5.1.0 (updated March 2011). The Cochrane Collaboration, 2011. Available from www.cochrane-handbook.org.
Schünemann 2011b
  • Schünemann HJ, Oxman AD, Vist GE, Higgins JPT, Deeks JJ, Glasziou P, et al. Chapter 12: Interpreting results and drawing conclusions. In: Higgins JPT, Green S (editors), Cochrane Handbook for Systematic Reviews of Interventions Version 5.1.0 (updated March 2011). The Cochrane Collaboration, 2011. Available from www.cochrane-handbook.org.
Smith 1978
Stankus 2000
  • Stankus SJ, Dlugopolski M, Packer D. Management of herpes zoster (shingles) and postherpetic neuralgia. American Family Physician 2000;61(8):2437-44, 2447-8.
Volmink 1996
Ware 1998
Wood 1994b

References to other published versions of this review

  1. References to studies included in this review
  2. References to studies excluded from this review
  3. References to studies awaiting assessment
  4. Additional references
  5. References to other published versions of this review
He 2006
  • He L, Zhang D, Zhou M, Zhu C. Corticosteroids for preventing postherpetic neuralgia. Cochrane Database of Systematic Reviews 2006, Issue 1. [DOI: 10.1002/14651858.CD005582]
He 2008
He 2010