Get access

Higher versus lower amino acid intake in parenteral nutrition for newborn infants

  • Protocol
  • Intervention

Authors


Abstract

This is the protocol for a review and there is no abstract. The objectives are as follows:

To determine whether higher versus lower intake of amino acid is associated with improved growth and disability free survival in newborn infants receiving parenteral nutrition.

Seconday objectives include to determine if:

  • higher versus lower starting or initial intake of amino acids is associated with improved growth and disability free survival without toxicity or side effects;

  • higher versus lower intake of amino acids at maximal intake is associated with improved growth and disability free survival without toxicity or side effects;

  • the increase in amino acid intake should replace non-protein energy intake (glucose and lipid), be in addition to non-protein energy intake, or be increased simultaneously with non-protein energy intake.

In subgroup analyses, additional objectives are to determine whether the effect of higher versus lower intake of amino acids is affected by gestational age, birth weight, age at commencement, condition of the infant or concomitant increases in fluid intakes.

Get access to the full text of this article

Ancillary