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Lamotrigine for chronic neuropathic pain and fibromyalgia in adults

  1. Philip J Wiffen*,
  2. Sheena Derry,
  3. R Andrew Moore

Editorial Group: Cochrane Pain, Palliative and Supportive Care Group

Published Online: 3 DEC 2013

Assessed as up-to-date: 26 NOV 2013

DOI: 10.1002/14651858.CD006044.pub4


How to Cite

Wiffen PJ, Derry S, Moore RA. Lamotrigine for chronic neuropathic pain and fibromyalgia in adults. Cochrane Database of Systematic Reviews 2013, Issue 12. Art. No.: CD006044. DOI: 10.1002/14651858.CD006044.pub4.

Author Information

  1. University of Oxford, Pain Research and Nuffield Department of Clinical Neurosciences (Nuffield Division of Anaesthetics), Oxford, Oxfordshire, UK

*Philip J Wiffen, Pain Research and Nuffield Department of Clinical Neurosciences (Nuffield Division of Anaesthetics), University of Oxford, Pain Research Unit, Churchill Hospital, Oxford, Oxfordshire, OX3 7LE, UK. phil.wiffen@ndcn.ox.ac.uk.

Publication History

  1. Publication Status: Stable (no update expected for reasons given in 'What's new')
  2. Published Online: 3 DEC 2013

SEARCH

[Figure 1]
Figure 1. Study flow diagram.
[Figure 2]
Figure 2. Risk of bias summary: review authors' judgements about each risk of bias item for each included study.
[Figure 3]
Figure 3. Forest plot of comparison: 1 Painful diabetic neuropathy, outcome: 1.1 50% pain relief.
[Figure 4]
Figure 4. Forest plot of comparison: 2 All conditions: lamotrigine versus placebo, outcome: 2.2 Rash.
[Analysis 1.1]
Analysis 1.1. Comparison 1 Painful diabetic neuropathy: lamotrigine versus placebo, Outcome 1 50% pain relief.
[Analysis 2.1]
Analysis 2.1. Comparison 2 All conditions: lamotrigine versus placebo, Outcome 1 At least one adverse event.
[Analysis 2.2]
Analysis 2.2. Comparison 2 All conditions: lamotrigine versus placebo, Outcome 2 Rash.