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Antibiotics for clinically diagnosed acute rhinosinusitis in adults

  • Protocol
  • Intervention

Authors

  • An IM De Sutter,

    Corresponding author
    1. Ghent University, Department of General Practice and Primary Health Care, Ghent, Belgium
    2. Ghent University, Heymans Institute of Pharmacology, Ghent, Belgium
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  • Marieke B Lemiengre,

    1. Ghent University, Department of General Practice and Primary Health Care, Ghent, Belgium
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  • Dan Merenstein,

    1. Georgetown University Medical Center, Department of Family Medicine, Washington, DC, USA
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  • James Young,

    1. University Hospital Basel, Basel Institute for Clinical Epidemiology, Basel, Switzerland
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  • Mieke L van Driel

    1. Ghent University, Department of General Practice and Primary Health Care, Ghent, Belgium
    2. The University of Queensland, Discipline of General Practice, School of Medicine, Brisbane, Queensland, Australia
    3. Bond University, Centre for Research in Evidence-Based Practice, Gold Coast, QLD, Australia
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Abstract

This is the protocol for a review and there is no abstract. The objectives are as follows:

  1. To determine the efficacy of antibiotics compared to placebo, in reducing duration or severity of general and specific rhinosinusitis symptoms in patients with clinically suspected acute rhinosinusitis.

  2. To determine if antibiotics have any influence on outcomes for patients with acute clinically diagnosed rhinosinusitis.

  3. To determine whether there are significant adverse outcomes associated with placebo therapy for patients with clinically diagnosed rhinosinusitis.

  4. To determine whether there are significant adverse effects with antibiotic therapy for patients with clinically diagnosed rhinosinusitis.