Intervention Review

Cholecystectomy for patients with silent gallstones

  1. Kurinchi Selvan Gurusamy1,*,
  2. Kumarakrishnan Samraj2

Editorial Group: Cochrane Hepato-Biliary Group

Published Online: 21 JAN 2009

Assessed as up-to-date: 18 MAY 2008

DOI: 10.1002/14651858.CD006230.pub2

Database Title

Additional Information

How to Cite

Gurusamy KS, Samraj K. Cholecystectomy for patients with silent gallstones. Cochrane Database of Systematic Reviews 2007, Issue 1. Art. No.: CD006230. DOI: 10.1002/14651858.CD006230.pub2.

Author Information

  1. 1

    Royal Free Hospital and University College School of Medicine, University Department of Surgery, London, UK

  2. 2

    John Radcliffe Hospital, Department of General Surgery, Oxford, UK

*Kurinchi Selvan Gurusamy, University Department of Surgery, Royal Free Hospital and University College School of Medicine, 9th Floor, Royal Free Hospital, Pond Street, London, NW3 2QG, UK. kurinchi2k@hotmail.com.

Publication History

  1. Publication Status: New search for studies and content updated (no change to conclusions)
  2. Published Online: 21 JAN 2009

SEARCH

ARTICLE TOOLS

View Full Article (HTML) Summary (57K)Standard (201K)Full (207K)
 

Abstract

  1. Top of page
  2. Abstract
  3. Plain language summary
  4. 摘要

Background

Cholecystectomy is currently advised only for patients with symptomatic gallstones. However, about 4% of patients with asymptomatic gallstones develop symptoms including cholecystitis, obstructive jaundice, pancreatitis, and gallbladder cancer.

Objectives

To assess the benefits and harms of surgical removal of the gallbladder for patients with asymptomatic gallstones.

Search methods

We searched The Cochrane Hepato-Biliary Group Controlled Trials Register, the Cochrane Central Register of Controlled Trials (CENTRAL) in The Cochrane Library, MEDLINE, EMBASE, and Science Citation Index Expanded until May 2008.

Selection criteria

Only randomised clinical trials (irrespective of language, blinding, or publication status) comparing cholecystectomy and no cholecystectomy were considered for the review.

Data collection and analysis

We were unable to identify any randomised clinical trials comparing cholecystectomy versus no cholecystectomy.

Main results

We were unable to identify any randomised clinical trial comparing cholecystectomy versus no cholecystectomy.

Authors' conclusions

There are no randomised trials comparing cholecystectomy versus no cholecystectomy in patients with silent gallstones. Further evaluation of observational studies, which measure outcomes such as obstructive jaundice, gallstone-associated pancreatitis, and/or gall-bladder cancer for sufficient duration of follow-up is necessary before randomised trials are designed in order to evaluate whether cholecystectomy or no cholecystectomy is better for asymptomatic gallstones.

 

Plain language summary

  1. Top of page
  2. Abstract
  3. Plain language summary
  4. 摘要

No evidence to assess surgical treatment in asymptomatic gallstones

Cholecystectomy is currently advised only for symptomatic gallstones. However, about 4% of patients with asymptomatic gallstones develop symptoms including cholecystitis, obstructive jaundice, pancreatitis, and gallbladder cancer. Literature search was performed for evidence from randomised clinical trials to find whether cholecystectomy was indicated in patients with silent (asymptomatic) gallstones. There is no randomised trial comparing cholecystectomy versus no cholecystectomy in silent gallstones. Further evaluation of observational studies, which measure outcomes such as obstructive jaundice, gallstone-associated pancreatitis, and/or gall-bladder cancer for sufficient duration of follow-up is necessary before randomised trials are designed in order to evaluate whether cholecystectomy or no cholecystectomy is better for asymptomatic gallstones.

 

摘要

  1. Top of page
  2. Abstract
  3. Plain language summary
  4. 摘要

背景

膽囊切除術治療無症狀膽囊結石病人

目前膽囊切除僅建議用於有症狀性膽囊結石的病人。但大約4%的患有無症狀膽囊結石的病人會發展成膽囊炎、阻塞性黃疸、胰腺炎和膽囊癌等症狀。

目標

評估手術移除膽囊對患有無症狀膽囊結石的病人的利弊

搜尋策略

使用Cochrane 肝膽小組蒐尋策略搜尋2006年以前的The Cochrane HepatoBiliary Group Controlled Trials Register, Cochrane Library的Cochrane Central Register of Controlled Trials (CENTRAL) 、MEDLINE、 EMBASE和Science Citation Index Expanded，找出隨機試驗。

選擇標準

本文獻回顧只考慮收納比較膽囊切除和非膽囊切除的隨機臨床試驗 (不受語言，盲法或發表狀況的限制)。

資料收集與分析

沒有找到任何比較膽囊切除和非膽囊切除的隨機臨床試驗。

主要結論

沒有找到任何比較膽囊切除和非膽囊切除的隨機臨床試驗。

作者結論

沒有任何針對無症狀膽囊結石病人比較膽囊切除和非膽囊切除的隨機臨床試驗。為了評估對於無症狀膽囊結石膽囊切除是否比不切除更有利，需要在設計隨機試驗之前，在追蹤時間夠久的情況下，須要進一步評估測量包括如阻塞性黃疸、膽囊結石相關的胰腺炎和膽囊癌等結果的觀察性研究。

翻譯人

此翻譯計畫由臺灣國家衛生研究院(National Health Research Institutes, Taiwan)統籌。

總結

沒有證據評估無症狀膽囊結石的手術治療。膽囊切除僅建議用於患有症狀性膽囊結石的病人。然而大約4%的無症狀膽囊結石的病人會發展成膽囊炎、阻塞性黃疸、胰腺炎和膽囊癌等症狀。文獻搜尋對無症狀膽囊結石病人採用膽囊切除的隨機臨床試驗。結果沒有找到對無症狀膽囊結石膽囊切除和不膽囊切除比較的隨機試驗。為了評估是否膽囊切除或非膽囊切除對於無症狀膽囊結石更有利，需要在設計隨機試驗之前，在追蹤時間夠久的情況下，須要進一步評估測量包括如阻塞性黃疸、膽囊結石相關的胰腺炎和膽囊癌等結果的觀察性研究。

View Full Article (HTML) Summary (57K)Standard (201K)Full (207K)