Pharmacotherapy for prevention of post-traumatic stress disorder

  • Protocol
  • Intervention

Authors

  • Jonathan C Ipser,

    Corresponding author
    1. University of Stellenbosch, MRC Research Unit for Anxiety and Stress Disorders, Tygerberg, Western Cape, South Africa
    • Jonathan C Ipser, MRC Research Unit for Anxiety and Stress Disorders, University of Stellenbosch, PO Box 19063, Tygerberg, Western Cape, 7505, South Africa. jonathan.ipser@uct.ac.za.

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  • Soraya Seedat,

    1. University of Stellenbosch, MRC Research Unit for Anxiety and Stress Disorders, Tygerberg, Western Cape, South Africa
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  • Dan J Stein

    1. University of Cape Town, Department of Psychiatry and Mental Health, Cape Town, South Africa
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Abstract

This is the protocol for a review and there is no abstract. The objectives are as follows:

1) To provide an estimate of the efficacy of medication in preventing the development of post-traumatic stress disorder following exposure to a traumatic event. The efficacy of medication in reducing symptom severity for those individuals who subsequently develop PTSD will also be considered.

2) To determine whether particular classes of medication are more effective and/or acceptable than others in the prevention of PTSD.

3) To assess whether depression is a predictor of treatment response in the prevention of PTSD.