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Prebiotics in infants for prevention of allergy

  1. David A Osborn1,*,
  2. John KH Sinn2

Editorial Group: Cochrane Neonatal Group

Published Online: 28 MAR 2013

Assessed as up-to-date: 23 AUG 2012

DOI: 10.1002/14651858.CD006474.pub3


How to Cite

Osborn DA, Sinn JKH. Prebiotics in infants for prevention of allergy. Cochrane Database of Systematic Reviews 2013, Issue 3. Art. No.: CD006474. DOI: 10.1002/14651858.CD006474.pub3.

Author Information

  1. 1

    University of Sydney, Central Clinical School, Discipline of Obstetrics, Gynaecology and Neonatology, Sydney, NSW, Australia

  2. 2

    Royal North Shore Hospital, The University of Sydney, Department of Neonatology, Sydney, New South Wales, Australia

*David A Osborn, Central Clinical School, Discipline of Obstetrics, Gynaecology and Neonatology, University of Sydney, Sydney, NSW, 2050, Australia. david.osborn@email.cs.nsw.gov.au.

Publication History

  1. Publication Status: New search for studies and content updated (conclusions changed)
  2. Published Online: 28 MAR 2013

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[Figure 1]
Figure 1. Risk of bias summary: review authors' judgements about each risk of bias item for each included study.
[Figure 2]
Figure 2. Funnel plot of comparison: 2 Prebiotic versus no prebiotic - according to infant risk of allergy, outcome: 2.2 Eczema.
[Figure 3]
Figure 3. Funnel plot of comparison: 3 Prebiotic versus no prebiotic - according to type of infant feed, outcome: 3.2 Eczema.
[Figure 4]
Figure 4. Funnel plot of comparison: 4 Prebiotic versus no prebiotic - according to type of prebiotic, outcome: 4.2 Eczema.
[Figure 5]
Figure 5.
[Analysis 1.1]
Analysis 1.1. Comparison 1 Prebiotic versus no prebiotic, Outcome 1 Asthma.
[Analysis 1.2]
Analysis 1.2. Comparison 1 Prebiotic versus no prebiotic, Outcome 2 Eczema.
[Analysis 1.3]
Analysis 1.3. Comparison 1 Prebiotic versus no prebiotic, Outcome 3 Urticaria.
[Analysis 2.1]
Analysis 2.1. Comparison 2 Prebiotic versus no prebiotic - according to infant risk of allergy, Outcome 1 Asthma.
[Analysis 2.2]
Analysis 2.2. Comparison 2 Prebiotic versus no prebiotic - according to infant risk of allergy, Outcome 2 Eczema.
[Analysis 2.3]
Analysis 2.3. Comparison 2 Prebiotic versus no prebiotic - according to infant risk of allergy, Outcome 3 Urticaria.
[Analysis 3.1]
Analysis 3.1. Comparison 3 Prebiotic versus no prebiotic - according to type of infant feed, Outcome 1 Asthma.
[Analysis 3.2]
Analysis 3.2. Comparison 3 Prebiotic versus no prebiotic - according to type of infant feed, Outcome 2 Eczema.
[Analysis 3.3]
Analysis 3.3. Comparison 3 Prebiotic versus no prebiotic - according to type of infant feed, Outcome 3 Urticaria.
[Analysis 4.1]
Analysis 4.1. Comparison 4 Prebiotic versus no prebiotic - according to type of prebiotic, Outcome 1 Asthma.
[Analysis 4.2]
Analysis 4.2. Comparison 4 Prebiotic versus no prebiotic - according to type of prebiotic, Outcome 2 Eczema.
[Analysis 4.3]
Analysis 4.3. Comparison 4 Prebiotic versus no prebiotic - according to type of prebiotic, Outcome 3 Urticaria.
[Analysis 5.1]
Analysis 5.1. Comparison 5 Specific prebiotic versus other prebiotic, Outcome 1 Polydextrose and GOS 4g/L versus polydextrose, GOS and lactulose 8g/L.