Intervention Protocol

Antiviral therapy for genital herpes for prevention of HIV transmission

  1. Brian E Ng1,*,
  2. George W Rutherford2,
  3. Angela L Broad2,
  4. David M Moore3

Editorial Group: Cochrane HIV/AIDS Group

Published Online: 15 JUN 2011

DOI: 10.1002/14651858.CD006492.pub2

How to Cite

Ng BE, Rutherford GW, Broad AL, Moore DM. Antiviral therapy for genital herpes for prevention of HIV transmission (Protocol). Cochrane Database of Systematic Reviews 2011, Issue 6. Art. No.: CD006492. DOI: 10.1002/14651858.CD006492.pub2.

Author Information

  1. 1

    The University of British Columbia, School of Population and Public Health, Vancouver, BC, Canada

  2. 2

    University of California, San Francisco, Global Health Sciences, San Francisco, California, USA

  3. 3

    University of British Columbia, BC Centre for Excellence in HIV/AIDS, Vancouver, British Columbia, Canada

*Brian E Ng, School of Population and Public Health, The University of British Columbia, Vancouver, BC, Canada. ng.brian.e@gmail.com.

Publication History

  1. Publication Status: Amended to reflect a change in scope (see 'What's new')
  2. Published Online: 15 JUN 2011

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Abstract

  1. Top of page
  2. Abstract

This is the protocol for a review and there is no abstract. The objectives are as follows:

To assess the effects of treatment or prophylaxis of HSV infection on HIV transmission in three situations:

  1. For persons (heterosexual or homosexual) with HIV and HSV infection, the effects of suppressing HSV to decrease HIV shedding and the risk of transmission of HIV to HIV-uninfected partners;
  2. For persons (heterosexual or homosexual) without HIV but with HSV, the effects of suppressing HSV on the risk of acquiring HIV from an HIV-infected partner;
  3. For persons (heterosexual or homosexual) without either HIV or HSV, the effects of treatment with antiviral medications of these persons to reduce the risk of acquiring HSV and HIV from their HSV- and HIV-infected partners; and
  4. For persons (heterosexual or homosexual) with HIV and HSV infection, the effects of episodic treatment of genital ulcers on HIV shedding and the risk of transmission of HIV to HIV-uninfected partners.