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Quetiapine versus other atypical antipsychotics for schizophrenia

  1. Laila Asmal1,*,
  2. Srnka J Flegar1,
  3. Jikun Wang2,
  4. Christine Rummel-Kluge3,
  5. Katja Komossa4,
  6. Stefan Leucht5

Editorial Group: Cochrane Schizophrenia Group

Published Online: 18 NOV 2013

Assessed as up-to-date: 7 MAY 2010

DOI: 10.1002/14651858.CD006625.pub3


How to Cite

Asmal L, Flegar SJ, Wang J, Rummel-Kluge C, Komossa K, Leucht S. Quetiapine versus other atypical antipsychotics for schizophrenia. Cochrane Database of Systematic Reviews 2013, Issue 11. Art. No.: CD006625. DOI: 10.1002/14651858.CD006625.pub3.

Author Information

  1. 1

    University of Stellenbosch, Department of Psychiatry, Tygerberg, South Africa

  2. 2

    East China Normal University, School of Psychology and Cognitive Science, Shanghai, China

  3. 3

    University of Leipzig, Clinic and Outpatient Clinic of Psychiatry and Psychotherapy, Leipzig, Saxony, Germany

  4. 4

    University Hospital of Zurich, Department of Psychiatry and Psychotherapy, Zurich, Switzerland

  5. 5

    Technische Universität München Klinikum rechts der Isar, Klinik und Poliklinik für Psychiatrie und Psychotherapie, München, Germany

*Laila Asmal, Department of Psychiatry, University of Stellenbosch, Faculty of Medicine and Health Sciences, PO Box 19063, Tygerberg, 7505, South Africa. laila@sun.ac.za.

Publication History

  1. Publication Status: New search for studies and content updated (no change to conclusions)
  2. Published Online: 18 NOV 2013

SEARCH

References

References to studies included in this review

  1. References to studies included in this review
  2. References to studies excluded from this review
  3. References to studies awaiting assessment
  4. References to ongoing studies
  5. Additional references
  6. References to other published versions of this review
Astrazeneca 1998 {published data only}
  • Astrazeneca 1998. A multicentre, double-blind randomised comparison of seroquel (TM) and risperidone in the treatment of schizophrenic patients with acute exacerbation. Astrazeneca trial data.
Atmaca 2003 {published data only}
Byerly 2008 {published data only}
  • Byerly MJ, Nakonezny PA, Rush AJ. Sexual functioning associated with quetiapine switch vs. risperidone continuation in outpatients with schizophrenia or schizoaffective disorder: a randomized double-blind pilot trial. Psychiatry Research 2008;159:115-20.
Canuso 2008 {published data only}
  • Canuso C, Carothers J, Dirks B, Zhu Y, Kosik-Gonzalez C. A double-blind, placebo-controlled trial of paliperidone ER and quetiapine in patients with a recent acute exacerbation of schizophrenia. Proceedings of the American Psychiatric Association 161st Annual Meeting, Washington, DC, May 3-6, 2008.
  • Canuso C, Dirks B, Carothers J, Zhu Y, Kosik-Gonzalez C. A comparative analysis of paliperidone ER and quetiapine in patients with a recent, acute exacerbation of schizophrenia. Schizophrenia Research 2008;98:158-9.
  • Canuso C, Dirks B, Carothers J, Zhu Y, Kosik-Gonzalez C. A double-blind, placebo controlled trial of paliperidone ER and quetiapine in patients with a recent acute exacerbation of schizophrenia. Proceedings of the 14th Biennial Winter Workshop on Schizophrenia and Bipolar Disorders, Montreux, Switzerland, February 3-7, 2007.
  • Canuso C, Dirks B, Carothers J, Zhu Y, Kosik-Gonzalez C. A double-blind, placebo-controlled trial of paliperidone ER and quetiapine in patients with a recent acute exacerbation of schizophrenia. Proceedings of the 20th Annual U.S. Psychiatric & Mental Health Congress, Orlando, FL, October 11-14, 2007.
  • Canuso CM, Dirks B, Carothers ScD, Kosik-Gonzalez C, Bossie CA, Zhu Y, et al. Randomized, double-blind, placebo-controlled study of paliperidone extended-release and quetiapine in inpatients with recently exacerbated schizophrenia. American Journal of Psychiatry 2009;AiA:1-11.
Conley 2005 {published data only}
  • Conley RR, Kelly DL, Nelson MW, Richardson CM, Feldman S, Benham R, et al. Risperidone, quetiapine, and fluphenazine in the treatment of patients with therapy-refractory schizophrenia. Clinical Neuropharmacology 2005;28(4):163-8.
  • Kelly DL, Conley RR. A randomized double-blind 12-week study of quetiapine, risperidone or fluphenazine on sexual functioning in people with schizophrenia. Psychoneuroendocrinology 2006;31(3):340-6.
  • Kelly DL, Conley RR. Thyroid function in treatment-resistant schizophrenia patients treated with quetiapine, risperidone, or fluphenazine. Journal of Clinical Psychiatry 2005;66:80-4.
  • Richardson CM, Kelly DL, Gold JM, McMahon R, Yu Y, Conley RR. Risperidone vs quetiapine vs fluphenazine in treatment-resistant schizophrenia: neuropsychological outcome. Schizophrenia Bulletin 2005;31:501-2.
Deberdt 2008 {published data only}
  • Deberdt W, Lipkovich I, Heinloth AN, Liu L, Kollack-Walker S, Edwards SE, et al. Double-blind, randomized trial comparing efficacy and safety of continuing olanzapine versus switching to quetiapine in overweight or obese patients with schizophrenia or schizoaffective disorder. Therapeutics and Clinical Risk Management 2008;4(4):713–20.
Eerdekens 2007 {published data only}
  • Eerdekens M, Kramer M, Cleton A, Vanderbosch A, Natarajan J, Earnest J, et al. Proceedings of the 20th European College of Neuropsychopharmacology, Vienna, Austria, October 13-17, 2007.
  • Hough DW, Natarajan J, Vandebosch A, Rossenu S, Kramer M, Eerdekens M. Evaluation of the effect of paliperidone extended release and quetiapine on corrected QT intervals: a randomized, double-blind, placebo-controlled study. International Clinical Psychopharmacology 2010;0(0):1-10. .
Hatta 2009 {published data only}
  • Hatta K, Sato K, Hamakawa H, Takebayashi H, Kimura N, Ochi S, et al. Effectiveness of second-generation antipsychotics with acute-phase schizophrenia. Schizophrenia Research 2009;113:49-55.
Hu 2008 {published data only}
  • Hu GH, Wu YJ, Li QX. A comparative study between quetiapine and risperidone in the treatment of first-episode schizophrenia. Chinese Medical Journal of Metallurgical Industry 2008;25(1):16-7.
Kinon 2006b {published data only}
  • Kinon BJ, Liu-Siefert H, Hill AL, Roychowdhury S, Edwards SB. Superiority of olanzapine versus quetiapine in improving overall functioning in patients with schizophrenia. Proceedings of the 16th European College of Neuropsychopharmacology Congress, September 20-24, 2003.
  • Kinon BJ, Noordsy DL, Liu-Seifert H, Gulliver AH, Ascher-Svanum H, Kollack-Walker S. Randomized, double-blind 6-month comparison of olanzapine and quetiapine in patients with schizophrenia or schizoaffective disorder with prominent negative symptoms and poor functioning. Journal of Clinical Psychopharmacology 2006;26(5):453-61.
Li 2002 {published data only}
  • Li Y, Wang CH, Zhang DH, Wang LH, Zhao Z. A study of quetiapine and clozapine in treatment of first-episode schizophrenia. Chinese Journal of Nervous and Mental Diseases 2002;28:219-20.
Li 2003 {published data only}
  • Li CH. A study of quetiapine and clozapine in treatment of schizophrenia. Chinese Journal of Nervous and Mental Diseases 2003;29:306-7.
Li 2005 {published data only}
  • Li Y, Feng YG. A double blind comparing study between the effects of quetiapine and clozapine on the life quality of the patients with schizophrenia. Medical Journal of Chinese Peoples Health 2005;17:262-4.
Lieberman 2005 {published data only}
  • * Lieberman JA, Stroup TS, McEvoy JP, Swartz MS, Rosenheck RA, Perkins DO, et al. Effectiveness of antipsychotic drugs in patients with chronic schizophrenia. New England Journal of Medicine 2005;353(12):1209-23.
  • Chwastiak LA, Rosenheck RA, McEvoy JP, Stroup TS, Swartz MS, Davis SM, et al. The impact of obesity on health care costs among persons with schizophrenia. General Hospital Psychiatry 2009;31:1-9.
  • Daumit GL, Goff DC, Meyer JM, Davis VG, Nasrallah HA, McEvoy JP, et al. Antipsychotic effects on estimated 10-year coronary heart disease risk in the CATIE schizophrenia study. Schizophrenia Research 2008;105:178-87.
  • Keefe RSE, Bilder RM, Davis SM, Harvey PD, Palmer BW, Gold JM, et al. Neurocognitive effects of antipsychotic medications in patients with chronic schizophrenia in the CATIE trial. Archives of General Psychiatry 2007;64:633-47.
  • Keefe RSE, Sweeney JA, Gu H, Hamer RM, Perkins DO, McEvoy JP, et al. Effects of olanzapine, quetiapine, and risperidone on neurocognitive function in early psychosis: a randomized, double-blind 52-week comparison. American Journal of Psychiatry 2007;164:1061-71.
  • Meyer JM, Davis VG, McEvoy JP, Goff DC, Nasrallah HA, Davis SM, et al. Impact of antipsychotic treatment on nonfasting triglycerides in the CATIE schizophrenia trial phase 1. Schizophrenia Research 2008;103:104-9.
  • Meyer JM, McEvoy JP, Davis VG, Goff DC, Nasrallah HA, Davis SM, et al. Inflammatory markers in schizophrenia: comparing antipsychotic effects in phase 1 of the clinical antipsychotic trials of intervention effectiveness study. Biological Psychiatry 2006;66:1013-22.
  • Meyer JM, Nasrallah HA, McEvoy JP, Goff DC, Davis SM, Chakos M, et al. The clinical antipsychotic trials of intervention effectiveness (CATIE) schizophrenia trial: clinical comparison of subgroups with and without the metabolic syndrome. Schizophrenia Research 2005;80:9-18.
  • Miller DD, Caroff SN, Davis SM, Rosenheck RA, McEvoy JP, Saltz BL, et al. Extrapyramidal side-effects of antipsychotics in a randomised trial. The British Journal of Psychiatry 2008;193:279-88.
  • Miller DD, McEvoy JP, Davis SM, Caroff SN, Saltz BL, Chakos MH, et al. Clinical correlates of tardive dyskinesia in schizophrenia: baseline data from the CATIE schizophrenia trial. Schizophrenia Research 2005;80:33-43.
  • Mohamed S, Rosenheck R, McEvoy J, Swartz M, Stroup S, Lieberman JA. Cross-sectional and longitudinal relationships between insight and attitudes toward medication and clinical outcomes in chronic schizophrenia. Schizophrenia Bulletin 2009;35(2):336-46.
  • Mohamed S, Rosenheck R, Swartz M, Stroup S, Lieberman JA, Keefe RSE. Relationship of cognition and psychopathology to functional impairment in schizophrenia. American Journal of Psychiatry 2008;165:978-87.
  • Nasrallah HA. Metabolic findings from the CATIE trial and their relation to tolerability. CNS Spectrum 2006;11(7 Suppl 7):32-9.
  • Patel JK, Buckley PF, Woolson S, Hamer RM, McEvoy JP, Perkins DO, et al. Metabolic profiles of second-generation antipsychotics in early psychosis: findings from the CAFE study. Schizophrenia Research 2009;111:9-16.
  • Penn DL, Keefe RSE, Davis SM, Meyer PS, Perkins DO, Losardo D, et al. The effects of antipsychotic medications on emotion perception in patients with chronic schizophrenia in the CATIE trial. Schizophrenia Research 2009;115:17-23.
  • Perkins DO, Gu H, Weiden PJ, McEVoy JP, Hamer RM, Lieberman JA. Predictors of treatment discontinuation and medication nonadherence in patients recovering from a first episode of schizophrenia, schizophreniform disorder, or schizoaffective disorder: a randomised, double-blind, flexible-dose, multicenter study. J Clin Psychiatry 2008;69(1):106-13.
  • Perlick DA, Rosenheck RA, Kaczynski R, Swartz MS, Canive JM, Lieberman JA. Impact of antipsychotic medication on family burden in schizophrenia: longitudinal results of CATIE trial. Schizophrenia Research 2010;116:118-25.
  • Resnick SG, Rosenheck RA, Canive JM, Souza CD, Stroup TS, McEvoy J, et al. Employment outcomes in a randomised trial of second-generation antipsychotics and perphenazine in the treatment of individuals with schizophrenia. Journal of Behavioral Health Services and Research 2008;35(2):215-25.
  • Rosenheck RA, Davis S, Covell N, Essock S, Swartz M, Stroup S, et al. Data from the CATIE Trial. Schizophrenia Research 2009;107:22-9.
  • Rosenheck RA, Davis VG, Davis SM, Stroup S, McEvoy J, Swartz M, et al. The CATIE schizophrenia trial. Schizophrenia Research 2009;113:12-8.
  • Stroup S, Appelbaum P, Swartz M, Patel M, Davis S, Jeste D, et al. Decision-making capacity for research participation among individuals in the CATIE schizophrenia trial. Schizophrenia Research 2005;80:1-8.
  • Stroup TS, Lieberman JA, McEvoy JP, Davis SM, Swartz MS, Keefe RSE, et al. Results of phase 3 of the CATIE schizophrenia trial. Schizophrenia Research 2009;107:1-12.
  • Swanson JW, Swartz MS, van Dorn RA, Volavka J, Monahan J, Stroup TS, et al. Comparison of antipsychotic medication effects on reducing violence in people with schizophrenia. The British Journal of Psychiatry 2008;193:37-43.
  • Swartz MS, Perkins DO, Stroup TS, Davis SM, Capuano G, Rosenheck RA, et al. Effects of antipsychotic medications on psychosocial functioning in patients with chronic schizophrenia: findings from the NIMH CATIE study. American Journal of Psychiatry 2007;164:428-36.
  • Swartz MS, Stroup TS, McEvoy JP, Davis SM, Rosenheck RA, Keefe RSE, et al. What CATIE found: results from the schizophrenia trial. Psychiatric Services 2008;59(5):500-6.
  • Swartz MS, Wagner HR, Swanson JW, Stroup TS, McEvoy JP, Reimherr F, et al. The effectiveness of antipsychotic medications in patients who use of avoid illicit substances: results from the CATIE study. Schizophrenia Research 2008;100:39-52.
Liu 2004 {published data only}
  • Liu Y, Xu M, Chen X. A controlled study of quetiapine and clozapine in the treatment of schizophrenia with predominantly negative symptoms. Shandong Archires of Psychiatry 2004;17(1):6-8.
Lu 2006 {published data only}
  • Lu X, Cheng H, Song S, Sun L, Zhang Y, Fan Y. A study of quetiapine and risperidone and clozapine in the treatment of schizophrenia. China and Foreign Medical Journal 2006;4(6):62-4.
Luo Xin 2008 {published data only}
  • Luo X, An BF. Comperison of quetiapine and aripiprazole in the treatment of first episode schizophrenia. Journal of Clinical Psychological Medicine 2008;18(3):191-2.
McEvoy 2006 {published data only}
  • McEvoy JP, Lieberman JA, Stroup TS, Davis SM, Meltzer HY, Rosenheck RA, et al. Effectiveness of clozapine versus olanzapine, quetiapine, and risperidone in patients with chronic schizophrenia who did not respond to prior atypical antipsychotic treatment. American Journal of Psychiatry 2006;163(4):600-10.
McEvoy 2007 {published data only}
  • Keefe R, Gu H, Sweeney J, Perkins D, McEvoy J, Hamer R, Lieberman J. A comparison of the effects of olanzapine, quetiapine, and risperidone on neurocognitive function in first-episode psychosis. Proceedings of the 44th Annual Meeting of the American College of Neuropsychopharmacology, Waikoloa, Hawaii, December 11-15, 2005.
  • Keefe RSE, Gu H, Sweeney JA, Perkins DO, McEvoy JP, Hamer RM, Lieberman JA. The effects of olanzapine, quetiapine and risperidone on neurocognitive function in first-episode psychosis: a double-blind 52-week comparison. Proceedings of the 159th Annual Meeting of the American Psychiatric Association, Toronto, Canada, May 20-25, 2006.
  • Keefe RSE, Sweeney JA, Gu H, Hamer RM, Perkins DO, McEvoy JP, et al. Effects of olanzapine, quetiapine, and risperidone on neurocognitive function in early psychosis: a randomized, double-blind 52-week comparison. American Journal of Psychiatry 2007;164:1061-71.
  • Lieberman J, McEvoy JP, Perkins D, Hamer RH. Comparison of atypicals in first-episode psychosis: a randomized, 52-week comparison of olanzapine, quetiapine, and risperidone. Journal of the European College of Neuropsychopharmacology 2005;15(Suppl 3):S525.
  • McEvoy JP. Comparison of clozapine versus other atypical drugs in prospectively defined, unresponsive patients. Proceedings of the 159th Annual Meeting of the American Psychiatric Association, May 20-25, 2006, Toronto, Canada.
  • McEvoy JP, Lieberman JA, Perkins DO, Hamer RM, Gu H, Lazarus A, et al. Efficacy and tolerability of olanzapine, quetiapine, and risperidone in the treatment of early psychosis: a randomized, double-blind 52-week comparison. American Journal of Psychiatry 2007;164:1050-60.
  • McEvoy JP, Perkins DO, Gu H, Hamer RM, Lieberman JA. Clinical effectiveness and predictors of treatment non-adherence: comparison of olanzapine, quetiapine, and risperidone in first-episode psychosis. Schizophrenia Research 2006;86(Suppl 1):S130.
  • Patel JK, Buckley PF, Woolson S, Hamer RM, McEvoy JP, Perkins DO, et al. Metabolic profiles of second-generation antipsychotics in early psychosis: Findings from the CAFE study. Schizophrenia Research 2009;111:9-16.
  • Perkins DO, Gu H, Weiden PJ, McEVoy JP, Hamer RM, Lieberman JA. Predictors of treatment discontinuation and medication nonadherence in patients recovering from a first episode of schizophrenia, schizophreniform disorder, or schizoaffective disorder: a randomised, double-blind, flexible-dose, multicenter study. J Clin Psychiatry 2008;69(1):106-13.
Mori 2004 {published data only}
  • Mori K, Nagao M, Yamashita H, Morinobu S, Yamawaki S. Effect of switching to atypical antipsychotics on memory in patients with chronic schizophrenia. Progress in Neuro-Psychopharmacology and Biological Psychiatry 2004;28(4):659-65.
Ozguven 2004 {published data only}
  • Ozguven Hd, Oner O, Baskak B, Oner P, Atbasoglu EC. The metabolic and clinical effects of olanzapine and quetiapine: preliminary findings from a randomized single-blind trial in patients with schizophrenia. Schizophrenia Research 2004;67(1):190-1.
Peng 2007 {published data only}
  • Peng X, Huang Y, Liu XY. A clinical analysis of aripiprazole and quetiapine in treatment of first episode schizophrenia. Journal of Clinical Psychological Medicine 2007;17(5):329-30.
Potkin 2006 {published data only}
  • Gharabawi GM, Greenspan A, Rupnow MFT, Kosik-Gonzalez C, Bossie CA, Zhu Y, et al. Reduction in psychotic symptoms as a predictor of patient satisfaction with antipsychotic medication in schizophrenia: data from a randomized double-blind trial. BMC Psychiatry 2006;6(45):1-7.
  • Greenspan A, Kosik-Gonzalez C, Moreau-Mallet V, Bossie CA, Rupnow MFT, Zhu Y, Gharabawi GM. Risperidone vs quetiapine in inpatients with schizophrenia: a double-blind placebo-controlled study. Journal of the European College of Neuropsychopharmacology 2005;15(Suppl 3):S503.
  • Potkin SG, Gharabawi GM, Greenspan AJ, Mahmoud R, Kosik-Gonzalez C, Rupnow MFT, et al. A double-blind comparison of risperidone, quetiapine and placebo in patients with schizophrenia experiencing an acute exacerbation requiring hospitalization. Schizophrenia Research 2006;85(1-3):254-65.
  • Potkin SG, Greenspan A, Kosik-Gonzalez C, Bossie C, Rupnow M, Zhu Y, et al. A placebo-controlled study of risperidone vs quetiapine for symptom response and readiness for discharge among agitated inpatients with schizophrenia. Schizophrenia Bulletin 2005;31:501.
Riedel 2005 {published data only}
  • Riedel M, Muller N, Strassnig M, Spellmann I, Engel RR, Musil R, et al. Quetiapine has equivalent efficacy and superior tolerability to risperidone in the treatment of schizophrenia with predominantly negative symptoms. European Archives of Psychiatry and Clinical Neuroscience 2005;255(6):432-7.
  • Riedel M, Spellmann I, Muller N, Strassnig M, Muller-Arends A, Dehning S, Moller HJ. Cognitive benefits of quetiapine versus risperidone in schizophrenia. Proceedings of the 158th Annual Meeting of the American Psychiatric Association, Atlanta GA, USA, May 21-26, 2005.
  • Riedel M, Spellmann I, Strassnig M, Douhet A, Dehning S, Opgen-Rhein M, et al. Effects of risperidone and quetiapine on cognition in patients with schizophrenia and predominantly negative symptoms. European Archives of Psychiatry and Clinical Neuroscience 2007;257:360-70.
Riedel 2007 {published data only}
  • Riedel M, Müller N, Spellmann I, Engel RR, Musil R, Valdevit R, et al. Efficacy of olanzapine versus quetiapine on cognitive dysfunctions with an acute episode of schizophrenia. European Archieves of Psychiatry and Clinical Neuroscience 2007;257(7):402-12.
Sacchetti 2004 {published data only}
  • Sacchetti E, Valsecchi P, Regini C, Galluzo a, Cacciani P, Agrimi E, Mencacci C. Comparison of quetiapine, olanzapine and risperidone in patients with schizophrenia: interim results of a randomised, rater-blinded study. Schizophrenia Research 2004;67(1):150.
  • Sacchetti E, Valsecchi P, Regini C, Galluzzo A, Cacciani P. Comparison of quetiapine, olanzapine and risperidone in a randomized study in patients with schizophrenia. Proceedings of the Thematic Conference of the World Psychiatric Association on "Treatments in Psychiatry: An Update", Florence, Italy, November 10-13, 2004.
  • Sacchetti E, Valsecchi P, Regini C, Galluzzo A, Cacciani P, Agrimi E, Mencacci C. Comparison of quetiapine, olanzapine and risperidone in patients with schizophrenia: interim results of a randomised, rater-blinded study. Journal of the European College of Neuropsychopharmacology 2003;13(4):S350.
  • Sacchetti E, Valsecchi P, Regini C, Galluzzo A, Cacciani P, Agrimi E, Mencacci C. Comparison of quetiapine, olanzapine, and risperidone in schizophrenia. Journal of the European College of Neuropsychopharmacology 2004;14(Suppl 3):S286.
  • Sacchetti E, Valsecchi P, Regini C, Galluzzo A, Cacciani P, Agrimi E, et al. Comparison of quetiapine, olanzapine and risperidone in patients with schizophrenia: interim results of a randomised, rater-blinded study. Proceedings of the 16th European College of Neuropsychopharmacology Congress, Prague, Czech Republic, September 20-24, 2003.
Sirota 2006 {published data only}
Song 2008 {published data only}
  • Song GM, Li JH, Zhong H, Lu SL. Control study of risperidone oral solution and quetiapine on schizophrenia. Modern Journal of Integrated Traditional Chinese and Western Medicine 2008;17(32):4961-3.
Stroup 2006 {published data only}
  • Stroup TS, Lieberman JA, McEvoy JP, Swartz MS, Davis SM, Rosenheck RA, et al. Effectiveness of olanzapine, quetiapine, risperidone, and ziprasidone in patients with chronic schizophrenia following discontinuation of a previous atypical antipsychotic. American Journal of Psychiatry 2006;163(4):611-22.
Svestka 2003b {published data only}
  • Svestka J, Synek O, Zourkova A. A double-blind comparison of olanzapine and quetiapine in treatment of acute exacerbations of schizophrenic or schizoaffective disorders. Journal of the European College of Neuropsychopharmacology 2003;13(4):S291.
Voruganti 2007 {published data only}
  • Voruganti LP, Awad AG, Parker G, Forrest C, Usmani Y, Fernando MLD, et al. Cognition, functioning and quality of life in schizophrenia treatment: results of a one-year randomized controlled trial of olanzapine and quetiapine. Schizophrenia Research 2007; Vol. 96, issue 1:146-55.
Wang 2006 {published data only}
  • Wang DF, Wang XR. A control study of quetiapine and risperidone in the treatment of schizophrenia. Medical Journal of Chinese People's Health 2006;35(18):1697-8.
Wei 2006a {published data only}
  • Wei QW, Fang YR, Shen XL, Tian T, Liao JG, Fang XG. A comparative study of social function in first-episode schizophrenic patients treated with quetiapine and risperidone. Shandong Archives of Psychiatry 2006;19(1):34-6.
Wei 2006b {published data only}
  • Wei SZ, Tang QS, Xu ZN, Rang XJ, Lu B. Dummy parallel controlled study in the female first-episode schizophrenia treated with aripiprazole and quetiapine. Chinese Journal of Nervous and Mental Disorders 2006;32(6):511-7.
Zhong 2006 {published data only}
  • Harvey PD, Patterson TL, Potter LS, Zhong K, Brecher M. Improvement in social competence with short-term atypical antipsychotic treatment: a randomized, double-blind comparison of quetiapine versus risperidone for social competence, social cognition, and neuropsychological functioning. American Journal of Psychiatry 2006;163(11):1918-25.
  • Zhong KX, Sweitzer DE, Hamer RM, Lieberman JA. Comparison of quetiapine and risperidone in the treatment of schizophrenia: a randomized, double-blind, flexible-dose, 8-week study. Journal of Clinical Psychiatry 2006;67(7):1093-103.

References to studies excluded from this review

  1. References to studies included in this review
  2. References to studies excluded from this review
  3. References to studies awaiting assessment
  4. References to ongoing studies
  5. Additional references
  6. References to other published versions of this review
An 2003 {published data only}
  • An BF, Liu XQ, Chen JX. A comparative study between quetiapine and clozapine in the treatment of schizophrenia and the relation with the plasman levels of IL-2, SIL-2R. Schuan Mental Health 2003;16(3):152-4.
An 2006 {published data only}
  • An BF, Zhang ML, Qi SG. Comparitive study between the effect olanzapine and quetiapine in first-episode schizophrenia. Journal of Clinical Psychological Medicine 2006;16(2):84-5.
An 2006a {published data only}
  • An BF, Li Y, Wang CH. A study on the executive function of first episode paranoid schizophrenia. Chinese Journal of Behavioral Medical Science 2006;15(4):340-1.
Antonova 2005 {published data only}
  • Antonova E, Kumari V, Halari R, Zachariah E, Mehrotra R, Kumar A, et al. Superior cognitive efficacy of atypical antipsychotics olanzapine, risperidone, and quetiapine, as a group, relative to low doses of conventional antipsychotics. Schizophrenia Bulletin 2005;31:474.
Arango 2009 {published data only}
  • Arango C, Robles O, Parellada M, Fraguas D, Sancho-Ruiz A, Medina O, et al. Olanzapine compared to quetiapine in adolescents with a first psychotic episode. Eur Child Adolesc Psychiatry 2009;18:418-28.
Ascher-Svanum 2006 {published data only}
  • Ascher-Svanum H, Zhu B, Faries D, Landbloom R, Swartz M, Swanson J. Time to discontinuation of atypical versus typical antipsychotics in the naturalistic treatment of schizophrenia. BMC Psychiatry 2006;6(8):1-16.
Baloescu 2006 {published data only}
  • Baloescu A, Vasile D, Gheorghe MD, Grigorescu G. Side effects of atypical antipsychoticsprediction factor for compliance. Journal of the European College of Neuropsychopharmacology 2006;16(Suppl 4):S403.
Ban 2008 {published data only}
  • Ban N, Cui JB. Analysis of the efficacy of aripiprazole and quetiapine in the treatment of schizophrenia. Occupation and Health 2008;24(3):292-3.
Beuzen 2005 {published data only}
  • Beuzen J-N, Pans M, Modell S, Hagens P, McQuade R, Iwamoto T, et al. Naturalistic study of aripiprazole treatment. Proceedings of the XIII World Congress of Psychiatry, Cairo, Egypt, September 10-15, 2005.
Boter 2005 {published data only}
  • Boter H, Peuskens J, Libiger J, Fleischhacker WW, Davidson M, Galderisi S, Kahn RS. Effectiveness of antipsychotics in first-episode schizophrenia and schizophreniform disorder on response and remission: an open randomized clinical trial (EUFEST). Schizophrenia Research 2009;115:97-103.
  • Galderisi S, Davidson M, Kahn RS, Mucci A, Boter H, Gheorghe MD, et al. Correlates of cognitive impairment in first episode schizophrenia: the EUFEST study. Schizophrenia Research 2009;115:104-14.
  • Kahn RS, Fleischhacker WW, Boter H, Davidson M, Vergouwe Y, Keet IPM, et al. Effectiveness of antipsychotic drugs in first-episode schizophrenia and schizophreniform disorder: an open randomised clinical trial. Lancet 2008;371:1085–97.
Brecher 2007 {published data only}
  • Brecher M, Newcomer JW, Ratner RE, Eriksson JW, Emsley R, Meulien D, et al. Differential effects of quetiapine, olanzapine and risperidone on glucose metabolism: a 24-week study in schizophrenia. International Congress on Schizophrenia Research. 2007.
Byerly 1999 {published data only}
  • Byerly M, Weber M. Clozapine versus quetiapine for schizophrenia. Stanley Foundation Research Programs 1999.
Byerly 2006 {published data only}
  • Byerly MJ, Nakonezny P, Bugno R, Boles J. A randomized, double-blind pilot trial of switching to quetiapine vs. risperidone continuation in outpatients with risperidone-associated sexual dysfunction. Proceedings of the 159th Annual Meeting of the American Psychiatric Association, Toronto, Canada, May 20-25, 2006.
Cai 2005 {published data only}
  • Cai QQ, Wang ZW, Lin YC, Wang XY. A control study of quetiapine and clozapine in the treatment of schizophrenia. The Medicine Magazine of China 2005;3(8):465-6.
Canas 2006 {published data only}
  • Canas F, Perez V, Tafalla M. Quetiapine and risperidone in the treatment of schizophrenia: a short- and long-term, non-randomized study. Proceedings of the 159th Annual Meeting of the American Psychiatric Association, Toronto, Canada, May 20-25, 2006.
Cao 2005 {published data only}
  • Cao D, Xie S-P, Chen Q-B, Yuan Y-G, Fang Q. Characteristics of the sexual disturbance caused by chlorpromazine, risperidone, quetiapine and olanzapine and their associations with the changes of blood glucose and blood lipids in male patients with schizophrenia. Chinese Journal of Clinical Rehabilitation 2005;9(36):63-8.
Cao 2005 a {published data only}
  • Cao D, Xie S-P, Chen Q-B, Yuan Y-G, Fang Q. Comparison of the effects of chlorpromazine, risperidone and quetiapine on hypothalamic-pituitary-gonadal axis and sexual function in male patients with schizophrenia. Chinese Journal of Clinical Rehabilitation 2005;9(20):148-51.
Cao 2006a {published data only}
  • Cao D, Xie SP, Chen QB, Yuan YG, Fang Q. Effects of antipsychotic on pituitary-gonadal axis in male patients with schizophrenia. Journal of Clinical Psychological Medicine 2006;16(4):209-11.
Cao 2006d {published data only}
  • Cao CA, Guo JH, Gao H. Comparison of curative effect and safety of quetiapine and risperidone in the treatment of female schizophrenia. Medical Journal of Chinese People's Health 2006;18(6):433-4.
Chang 2007 {published data only}
  • Chang GS, Li J. A control study of quetiapine and risperidone in the treatment of schizophrenia. China Practice Medicine 2007;2(34):52-3.
Chang 2008 {published data only}
  • Chang YS, Gu YS. A control study of quetiapine and risperidone in the treatment of schizophrenia. Medical Journal of Chinese People's Health 2008;20(17):2010-1.
Chaudhry 2006 {published data only}
  • Chaudhry HR, Niaz S, Arshad N, Peracha F, Ayub A, Mufti KA. Comparison of risperidone, olanzapine and quetiapine in relation to body weight, serum blood glucose and prolactin levels. Journal of the European College of Neuropsychopharmacology 2006;16(Suppl 4):S241.
Chen 2006a {published data only}
  • Chen ZE, Liu HR, Wu SQ. A control study of quetiapine and risperidone in the treatment of female schizophrenia. Herald of Medicine 2006;25(6):548-50.
Chen 2006k {published data only}
  • Chen RY, Luo RQ, Wang AQ, Mei HB. A study of quetiapine on the quality of life of elderly schizophrenia. Medical Journal of Chinese People's Health 2006;18(6):447-8.
Chen 2007a {published data only}
  • Chen JG. Control study on management of first-episode schizophrenia with risperidone and quetiapine. China Pharmaceuticals 2007;16(9):43-4.
Chen 2007b {published data only}
  • Chen FX. A control study of quetiapine vs risperidone in first-episode schizophrenia. Jiangxi Medicine 2007;42(10):917-8.
Chen 2007c {published data only}
  • Chen F, Wang HY, Li DY, Zhou BW, Chen FY. A control study of quetiapine and aripiprazole in the treatment of female first-episode schizophrenia. Journal of Psychiatry 2007;20(6):381-3.
Chen 2008 {published data only}
  • Chen HB, Fu F, Yang QJ. A control study of quetiapine and risperidone in the treatment of schizophrenia. Medical Information 2008;21(3):389-90.
Chu 2006 {published data only}
  • Chu JP. Comparative study of quetiapine and risperidone in the treatment of late onset schizophrenias. Journal of Clinical Psychological Medicine 2006;16(1):34-5.
Cortese 2008 {published data only}
  • Cortese L, Caligiuri MP, Williams R, Schieldrop P, Manchanda R, Malla A, Harricharan R. Reduction in neuroleptic-induced movement disorders after a switch to quetiapine in patients with schizophrenia. J Clin Psychopharmacol 2008;28:69-73.
Dai 2004 {published data only}
  • Dai J-P, Zhao Z-H, Mai G-Y. Comparative study on the effect of olanzapine and seroquel of schizophrenia. Chinese Journal of Behavioral Medical Science 2004;13(3):291-3.
Dai 2005 {published data only}
  • Dai J-P, Zhao Z-H, Liu G-X. Comparison of efficacy and safety of aripiprazole and quetiapine in the treatment of schizophrenia. Chinese Journal of Behavioral Medical Sience 2005;14(8):712-14.
Dai 2008 {published data only}
  • Dai XG, Xia XL, Ye XR. The effects of seroquel and risperidone on serum prolactin levels of female schizophrenia. Chinese Journal of Modern Drug Application 2008;2(3):10-1.
Davies 2007 {published data only}
Ding 2004 {published data only}
  • Ding Y, An B, Li G, Li Y. A comparative study of risperidone and quetiapine in the treatment of schizophrenia and relationship between efficacy and the serum levels of il-2?sil-2r. Shandong Archives of Psychiatry 2004;17(2):76-8.
Dong 2008 {published data only}
  • Dong W, Yang X. A control study of quetiapine and ziprasidone in the treatment of first-episode schizophrenia. Medical Journal of Chinese People's Health 2008;20(12):1275-6.
Dossenbach 2005 {published data only}
  • Dossenbach M, Arango-Davila C, Silva Ibarra H, Landa E, Aguilar J, Caro O, et al. Response and relapse in patients with schizophrenia treated with olanzapine, risperidone, quetiapine, or haloperidol: 12-month follow-up of the intercontinental schizophrenia outpatient health outcomes (IC-SOHO) study. Journal of Clinical Psychiatry 2005;66:1021-30.
Du 2003 {published data only}
  • Feng D-J, Zhou T, Xiong L-H, Thian D-F. A study of quetiapine and clozapine in treatment of chronic schizophrenia. Journal of Luzhou Medical College 2003;26(6):511-12.
Emsley 2005 {published data only}
  • Emsley R, Turner HJ, Schronen J, Botha K, Smit R, Oosthuizen PP. Effects of quetiapine and haloperidol on body mass index and glycaemic control: a long-term, randomized, controlled trial. International Journal of Neuropsychopharmacology 2005;8(2):175-82.
Fan 2005 {published data only}
  • Fan J-H, Li W-J. A study of quetiapine in treatment of negative symptoms dominant schizophrenia. Sichuan Mental Health 2005;18:178.
Fan 2008 {published data only}
  • Fan BF, Chen CF, Xu Y, Cao PL, Gao P. The effects of quetiapine, risperidone and clozapine for schizophrenia on serum prolactin level. Chinese Medical Journal of Metallurgical Industry 2008;25(1):14-5.
Fleischhacker 2005 {published data only}
Fu 2005 {published data only}
  • Fu H, Yu H, Huo J. A comparative study of quetiapine vs clozapine in the treatment of schizophrenia. Journal of Clinical Psychosomatic Diseases 2005;11(4):313-4.
Fu 2005a {published data only}
  • Fu H, Yu H, Huo J. A comparative study of quetiapine vs clozapine in the treatment of schizophrenia. Journal of Clinical Psychosomatic Diseases 2005;11(4):313-4.
Gao 2003 {published data only}
  • Gao CZ, Gao Z. A study of quetiapine in the treatment of first-onset schizophrenia. Journal of Clinical Psychological Medicine 2003;13(4):221-2.
García 2006 {published data only}
  • García MC, Vidal M, Ramos R. Sexual side effects of antipsychotics and treatment adherence. Journal of the European College of Neuropsychopharmacology 2006;16(Suppl 4):S378.
Guo 2008 {published data only}
  • Guo ZY, Liu JM, Yang JZ, Guo H, Wang AQ. Efficacy quetiapine in the treatment of schizophrenic patients and effect on the quality of life. China Journal of Health Psychology 2008;16(5):544-6.
Hao 2007 {published data only}
  • Hao H. A control study of quetiapine and seroquel in the treatment of schizophrenia. Journal of Medical Forum 2007;28(15):60-1.
Harrigan 2004 {published data only}
  • Harrigan EP, Miceli JJ, Anziano R, Watsky E, Reeves KR, Cutler NR, et al. A randomized evaluation of the effects of six antipsychotic agents on QTC, in the absence and presence of metabolic inhibition. Journal of Clinical Psychopharmacology 2004;24(1):62-9.
He 2003 {published data only}
  • He J, Chen YX. A controlled study on quetiapine and clozapine in the treatment of schizophrenic patients. Medical Journal of Chinese Civil Administration 2003;15(6):335-6.
Horacek 2004 {published data only}
  • Horacek J, Seifertova D, Janu L, Petranova T. The effect of quetiapine on different domains of cognition and negative symptoms in schizophrenia. Proceedings of the Biennial Winter Workshop on Schizophrenia, February 7-13, 2004.
Huang 2003 {published data only}
  • Huang S-P, Ma Z-W, Guo B-Y. Effectiveness of quetiapine vs clozapine in the treatment of schizophrenia. Journal of Clinical Psychosomatic Diseases 2003;9(4):206-7.
Huang 2006 {published data only}
  • Huang X, Liu JY. Effects of clozapine and seroquel on the glucose metabolism in schizophrenic patients. Jiangxi Medicine 2006;41(5):264-6.
Huber 2004 {published data only}
Jiang 2006 {published data only}
  • Jiang ZX, He XY, He XC, Li LW, Peng ZE. A control study of quetiapine and aripiprozole in the treatment of schizophrenia. Journal of Clinical Research 2006;23(8):1327-8.
Karow 2002 {published data only}
Keks 2006 {published data only}
  • Keks NA, Tonso M, Tabone K, McHugh M, Thomas R, Tune P, Gelman M. Clinical experience with atypical antipsychotics in acute inpatient unit: focus on quetiapine. International Journal of Psychiatry in Clinical Practice 2006;10(2):1-4.
Kelemen 2006 {published data only}
  • Kelemen O, Nagy O, Máttyássy A, Kiss I, Janka Z, Kéri S. Do second-generation antipsychotics disrupt decision-making abilities in schizophrenia?. Journal of the European College of Neuropsychopharmacology 2006;16(Suppl 4):S430.
Kim 2004 {published data only}
  • Kim JG, Cho DH, Choi HK, Kim HJ, Cho JH, Kang SH, et al. The comparison of risperidone, olanzapine and quetiapine in the treatment of chronic schizophrenia and schizoaffective disorder. Journal of the European College of Neuropsychopharmacology 2004;14(Suppl 3):S245.
Knegtering 2004 {published data only}
  • Knegtering R, Castelein S, Bous H, Van Der Linde J, Bruggeman R, Kluiter H, et al. A randomized open-label study of the impact of quetiapine versus risperidone on sexual functioning. Journal of Clinical Psychopharmacology 2004;24(1):56-61.
Kolotkin 2008 {published data only}
  • Kolotkin RL, Corey-Lisle PK, Crosby RD, Kan HJ, McQuade RD. Changes in weight and weight-related quality of life in a multicentre, randomized trial of aripiprazole versus standard of care. European Psychiatry 2008;23:561-6.
Koponen 2008 {published data only}
  • Koponen. Study in Schizophrenic In-Patients Treated With Quetiapine Prolong or Oral Risperidone at Flexible Dose. Clinical Trial Registration Data 2008.
Kuang 2007 {published data only}
  • Kuang YH, Zhao L. A comparative study on the efficacy and weight gain between quetiapine and clozapine in the treatment of schizophrenia. Journal of Psychiatry 2007;20(4):217-8.
L'Italien 2007 {published data only}
  • L’Italien G, Hanssens L, Kan HJ, Baker RA, Marcus RN, McQuade RD, et al. Metabolic effects of aripiprazole versus olanzapine, quetiapine, or risperidone (the Star trial). Proceedings of the 11th International Congress on Schizophrenia Research, Colorado Springs, Colorado, USA, March 28-April 1, 2007.
Lan 2006 {published data only}
  • Lan GX, Li ZC, Liu R, Deng G, Wu YM, Xie GP. A control study of quetiapine and clozapine in the treatment of schizophrenia. Journal of Ganna Medical University 2006;26(6):850-2.
Li 2001 {published data only}
  • Li HF, Gu NF, Xie B, Li M, Zhang L, Cheng Y, Wang MJ. Quetiapine in treatment of schizophrenia: a randomized, controlled, multicentre study. Chinese Journal of New Drugs and Clinical Remedies 2001;20(4):260-3.
Li 2002a {published data only}
  • Li DG, Zheng MX, Zheng JJ. A comparative study between quetiapine and clozapine in the treatment of schizophrenia. Jiuheyuan Hospital of Shishou 2002;12(5):267-8.
Li 2003a {published data only}
  • Li CM. A comparison of cognitive function in the first-onset schizophrenia treated with quetiapine and clozapine. Medical Journal of Chinese People Health 2003;15(12):718-21.
Li 2003b {published data only}
  • Li X, Lao G, Cao L. Comparison of efficacy and safety of seroquel and resperidone in the treatment of schizophrenia. Chinese Journal of Behavioral Medical Science 2003;12(1):45-6.
Li 2005a {published data only}
  • Li H. A controlled study of schizophrenia treated with quetiapine and clozapine. Chinese Modern Medical and Clinical 2005;3(7):33-4.
Li 2005b {published data only}
  • Li G, Chen Q-G, Zhang Q-H. A comparison analysis on the efficacy of quetiapine and risperidone in cognitive function of schizophrenia. Chinese Journal of Behavioral Medical Science 2005;14(11):1007-8, 1036.
Li 2007a {published data only}
  • Li M, Lv W, Xing X. A control study of quetiapine and aripiprazole in the treatment of schizophrenia. Chinese Journal of Postgraduate Medicine 2007;30(11):49-50.
Li 2007h {published data only}
  • Li Q, Wang W, Chen C, Li YM. Comparison of efficacy and safety of seroquel and risperidone in the treatment of schizophrenia. Huaxi Pharmacy 2007;22(3):354-5.
Li 2008a {published data only}
  • Li G, Zuo J, Chen Q, Zhou H. A comparison analysis on the efficacy of quetiapine and risperidone in the treatment of schizophrenia. Tianjin Pharmacy 2008;20(1):42-4.
Li 2008b {published data only}
  • Li S. A control study of quetiapine and olanzapine in the treatment of schizophrenia. Journal of Nongken Medicine 2008;30(1):31-3.
Li 2008c {published data only}
  • Li W. Influence on the psychopathology and the quality of life of schizophrenia treated with risperidone, clozapine and quetiapine. Medical Information 2008;21(12):2253-5.
Li 2008d {published data only}
  • Li DM. The cross-check analysis of risperdal and quetiapine alleviating negative symptoms of schizophrenia. Laboratory Medicine and Clinic 2008;5(19):1162-3.
Liang 2008 {published data only}
  • Liang L, Wang D, Shen Y. Influence of quetiapine and clozapine on fasting blood glucose of first-episode schizophrenia. Practical Pharmacy and Clinical Remedies 2008;11(5):296-7.
Lin 2005 {published data only}
  • Lin Z. Analysis of therapeutic effect of quetiapine on schizophrenia patient. China Tropical Medicine 2005;5(6):1299.
Lin 2007 {published data only}
  • Lin H, Wang J. A study of quetiapine in the treatment of elderly schizophrenia. Qinghai Pharmacy 2007;37(4):67-8.
Liu 2003 {published data only}
  • Liu X, Lin L, Fan Y, Dong X. A comparative study of new anti-psychopathic drugs lead to gain weight. Medical Journal of Chinese People's Health 2003;15(4):230-1.
Liu 2003a {published data only}
  • Liu K, Wang X, Jiang L, Geng H, Cng X, Shi L, Zhao H. A control study of quetiapine and risperidone in the treatment of schizophrenia. Journal of Hebei Mental Health 2003;16(1):37-9.
Liu 2004a {published data only}
  • Liu Y, Xu M, Chen X. A controlled study of quetiapine and clozapine in the treatment of schizophrenia with predominantly negative symptoms. Shandong Archires of Psychiatry 2004;17(1):6-8.
Liu 2004b {published data only}
  • Liu Y, Xu M, Chen X. A controlled study of quetiapine and clozapine in the treatment of schizophrenia with predominantly negative symptoms. Shandong Archires of Psychiatry 2004;17(1):6-8.
Liu 2005 {published data only}
  • Liu CX, Liu SH, Tu ZM, Liu B. A study of quetiapine with small doze of clozapine in treatment of resistant schizophrenia. Medical Journal of Chinese People´s Health 2005;17:748-9.
Liu 2005a {published data only}
  • Liu H, Shi Y, Liu Z. A comparative study between quetiapine and risperidone in the treatment of schizophrenia. Journal of Heze Medical College 2005;17(1):15-6.
Liu 2006 {published data only}
  • Liu Z, Han J, Cheng Y, Yan M, Zhou H. Study on quetiapine fumarate and risperidone in the treatment of schizophrenia. Journal of Hebei Medical College for Continuing Education 2006;23(2):14-6.
Liu 2007 {published data only}
  • Liu B. Clinical study on quetiapine in treatment of refractory schizophrenia. China Modern Doctor 2007;45(18):24-5.
Liu 2008 {published data only}
  • Liu L, Hou Z, Guo Y. A control study of quetiapine and risperidone in the treatment of elderly schizophrenia. Medical Journal of Chinese People's Health 2008;20(7):639-40.
Lu 2005 {published data only}
  • Lu S, Zhang S-A, Ren Y. Comparative study on the psychopathology and the quality of life of schizophrenia treated with risperidone, clozapine and quetiapine. Journal of Nursing Science 2005;20(3):57-9.
Luo 2005 {published data only}
  • Luo Y, Zhang S-W, Wang A-Q. The comparative study of quetiapine and clozapine in the treatment of female schizophrene. Medical Journal of Chinese People Health 2005;17(6):269-70.
Lv 2008 {published data only}
  • Lv B, Wang J, Lin Y. A control study of quetiapine and risperidone in the treatment of eldly schizophrenia. Shandong Pharmacy 2008;48(16):91-2.
Mei 2006 {published data only}
  • Mei Y, Pan J, Ma P, Pan G. Clinical observation on acute excitation of schizophrenia treated with quetiapine. Chinese Nursing Research 2006;20(5):1176-7.
Mintzer 2004 {published data only}
  • Mintzer JE, Mullen JA, Sweitzer DE. A comparison of extrapyramidal symptoms in older outpatients treated with quetiapine or risperidone. Current Medical Research and Opinion 2004;20(9):1483-91.
Mullen 2001 {published data only}
  • Mullen J, Jibson MD, Sweitzer D. A comparison of the relative safety, efficacy, and tolerability of quetiapine and risperidone in outpatients with schizophrenia and other psychotic disorders: the quetiapine experience with safety and tolerability (QUEST) study. Clinical Therapeutics 2001;23(11):1839-54.
Musil 2006 {published data only}
  • Musil RL, Spellmann I, Riedel M, Douhet A, Dehning S, Maino K, et al. SNAP-25 gene polymorphisms and weight gain in schizophrenic patients treated with atypical antipsychotics. Journal of the European College of Neuropsychopharmacology 2006;16(Suppl 4):S415.
Nai 2007 {published data only}
  • Nai X, Hu X, Qiu W, Liu N, Wei H. Effect of quetiapine on cognitive function of patients with first episode schizophrenia. Journal of Medical Forum 2007;28(2):38-9.
Pan 2004 {published data only}
  • Pan M, Wang H, Zhang S. A controlled study of domestic quetiapine and risperidone in the treatment of first-episode schizophrenia. Journal of Clinical Psychosomatic Diseases 2004;10(4):244-6.
Pan 2004a {published data only}
  • Pan M, Zhang S-Q, Zhao Z. A comparative study of domestic quetiapine and risperidone in the treatment of schizophrenia. Medical Journal of Chinese Peoples Health 2004;16(10):597-8, 637.
Pan 2004b {published data only}
  • Pan M, Zhang S, Zhao Z. Influence of three antipsychotic drugs on electrocardiogram in patients with schizophrenia. Journal of XinXiang Medical College 2004;21:403-4.
Pan 2008 {published data only}
  • Pan W, Lin Z, Cheng B. A study of ziprasidone in the treatment of schizophrenia. Guide of China Medicine 2008;6(13):22-3.
Pang 2002 {published data only}
  • Pang D, Wang C, Cui A. Effect of quetiapine fumarate and clozapine on clinical rehabilitation of schizophrenia:a controlled study. Chinese Journal of Clinical Rehabilitation 2002;6(7):1007.
Peng 2004 {published data only}
  • Peng XX, Huang X. Control study of quetiapine on schizophrenia mainly with negative symptoms. Modern Journal of Integrated Traditional Chinese and Western Medicine 2004;13(12):1557-8.
Petty 2005 {published data only}
  • Petty F. Seroquel Therapy for Substance Use Disorders Comorbid With Schizophrenia. Clinical Trial Registration Data 2006.
Pfizer 2005 {published data only}
  • Pfizer. Effect and Safety of Ziprasidone Compared to Other Atypical Antipsychotic Drug in Schizophrenic Patients. Clinical Trial Registration Data 2005.
Qi 2004 {published data only}
  • Qi F, Wang L, Zhen Y. Comparison of efficacy and safety of quetiapine and risperidone in the treatment of schizophrenia. Shanghai Archives of Psychiatry 2004;16(2):78-9, 119.
Qian 2004 {published data only}
  • Qian D, Pan B, Yang G. Cost-effectiveness analysis of 3 kinds of therapeutic schemes for schizophrenia. Evaluation and Analysis of Drug Use in Hospital of China 2004;4(2):110-1.
Reznik 2004 {published data only}
  • Reznik I, Slavkin L, Shabash E, Shaked G, Kertzman S, Spivak B, et al. Quetiapine ("Seroquel") and olanzapine for acute treatment of patients with schizophrenia: an open-label, comparative study. Proceedings of the XXIV Collegium Internationale Neuro-Psychopharmacologicum; Paris, France, June 20-24, 2004. 1-4.
Riera 2004 {published data only}
  • Riera L, Tandon R, Stock EG, Kujawa MJ, Torbeyns AF, Borian FE. Broad effectiveness trial with aripiprazole. Proceedings of the Twelfth Biennial Winter Workshop on Schizophrenia, Davos, Switzerland, February 7-13, 2004.
Ruan 2005 {published data only}
  • Ruan J, Huang G. A control study of quetiapine and clozapine in the treatment of difficult-to-treat schizophrenia. Medical Journal of Chinese People's Health 2005;17(12):747-8.
Ryu 2006 {published data only}
  • Ryu SH, Jang WS, Cho EY, Kim SK, Lee DS, Hong KS. Association of leptin gene polymorphism with antipsychotic drug-induced weight gain. Journal of the European College of Neuropsychopharmacology 2006;16(Suppl 4):S419.
Sajatovic 2002 {published data only}
  • Sajatovic M, Mullen JA, Sweitzer D. Efficacy of quetiapine and risperidone against depressive symptoms in outpatients with psychotic disorders. Proceedings of the 155th Annual Meeting of the American Psychiatric Association, Philadelphia, Pennsylvania, USA, May 18-23, 2002.
Sarma 2008a {published data only}
  • Sarma K. Lurasidone HCl - A Long Term Phase 3 Study ofPatients With Chronic Schizophrenia (PEARL 3Ext). Clinical Trial Registration Data 2008.
Sheng 2006 {published data only}
  • Sheng D, Yang Y. A study of cognitive function about quetiapine and clozapine in the treatment of schizophrenia. Journal of Clinical Psychological Medicine 2006;16(5):304.
Song 2006 {published data only}
  • Song F. A control study of quetiapine and clozapine in the treatment of schizophrenia. Health Horizon·Medical Science Fascicule 2006;(7):91.
Song 2008a {published data only}
  • Song C, Wang H, Sun X. A control study of quetiapine and clozapine in the treatment of schizophrenia of quality of life. Journal of Clinical Psychological Medicine 2008;18(2):133-4.
Song 2008b {published data only}
  • Song G, Li Y. A control study of quetiapine and clozapine in the treatment of chronic schizophrenia. Medical Journal of Chinese People's Health 2008;20(23):2790.
Sun 2006a {published data only}
  • Sun T, Liu H. A control study of quetiapine and clozapine in the treatment of children's first-episode schizophrenia. Shandong Archives of Psychiatry 2006;19(2):141-2.
Sun 2006e {published data only}
  • Sun X, Zou S, Li Z, Han Z. Effect of cognitive function in first-episode schizophrenia treated with quetiapine. Journal of Clinical Psychological Medicine 2006;16(2):94-5.
Sun 2007a {published data only}
  • Sun Q, Zeng D, Chen K. Clinical comparative study of ziprasidone in the treatment of schizophrenia. Journal of Psychiatry 2007;20(3):150-1.
Sun 2007b {published data only}
  • Sun M, Liang F, Meng Y. A control study on quetiapine in gerontic first-episode schizophrenia. Journal of Chinese Psychosomatic Disorders 2007;13(5):407-8.
Sun 2007c {published data only}
  • Sun L, Wang Y. A control study of quetiapine and clozapine in the treatment of schizophrenia. China Practical Medicine 2007;2(21):97.
Sun 2008 {published data only}
  • Sun H, Jiao Y, Li J. A comparative study of quetiapine and risperidone in the treatment of old men with schizophrenia. Medical Journal of Chinese People's Health 2008;20(1):14-6.
Swadi 2010 {published data only}
  • Swadi HS, Craig BJ, Pirwani NZ, Black VC, Buchan JC, Bobier CM. A trial of quetiapine compared with risperidone in the treatment of first onset psychosis among 15- to 18-year-old adolescents. International Clinical Psychopharmacology 2010;25(1):1-6.
Swanson 2006 {published data only}
  • Swanson JW, Swartz MS, Van Dorn RA. Effectiveness of atypical antipsychotics for substance abuse in schizophrenia patients. Proceedings of the 159th Annual Meeting of the American Psychiatric Association, Toronto, Canada, May 20-25, 2006.
Tang 2003 {published data only}
  • Tang Y. A controlled study of schizophrenia treated with quetiapine and clozapine. Shanghai Archives of Psychiatry 2003;15(1):27-9.
Tang 2005 {published data only}
  • Tang Z-K, Xu C-M, Chen D. A comparative study of quetiapine and clozapine in the treatment of recurrent schizophrenia. Shandong Archives of Psychiatry 2005;18(3):167-8.
Tao 2008 {published data only}
  • Tao S, Chen Q, Yang C, Pan R, Pan T, Li L, Zhou W. A comparison of the effects on lipid metabolic among four different atypical antipsychotic agents. Journal of Youjiang Medical College 2008, (6):7-9.
Tian 2006 {published data only}
  • Tian B, Li J, Jing H, Zhang W, Liu Y. A comparative study between seroquel and risperidone in the treatment of schizophrenia. Shandong Archives of Psychiatry 2006;19(1):25-6.
Tian 2007 {published data only}
  • Tian C, Li Z. Control studies on the curative effect and influence of quetiapine and clozapine on quality of life of schizophrenics. J Clin Psychosom Disease 2007;13(2):133-4.
Tian 2008 {published data only}
  • Tian H, Zhu Q. A comparative study of new antipsychopathic drugs lead to gain weight. Medical Journal of Chinese People's Health 2008;20(18):2119-20.
Wang 2000 {published data only}
  • Wang M, Liu M, Lu L. A controlled study on seroquel and risperidone in the treatment of schizophrenic patients. Journal of Clinical Psychological Medicine 2000;10(4):200-1.
Wang 2004 {published data only}
  • Wang X. Comparative study of effects of quetiapine and clozapine on quality of life of schizophrenics. Journal of Clinical Psychosomatic Diseases 2004;10(3):167-8.
Wang 2004a {published data only}
  • Wang M, Han F, Ma H. Comparation of quetiapine and clozapine in treatment of patients with first-onset schizophrenia. Chinese Journal of Clinical Pharmacology and Therapeutics 2004;9(5):551-4.
Wang 2005 {published data only}
  • Wang C-H, Li Y, Liu X. Cognitive function and p300 potentials in first-episode schizophrenia treated with quetiapine and risperidone. Chinese Mental Health Journal 2005;19(5):333-6.
Wang 2005a {published data only}
  • Wang C-H, Li Y, Wang L-H, Pan M, ZHao Z, Mu J-L. Comparison of cognitive function and event related potentials in first episode schizophrenic treated with antipsychotic drugs. Journal of Clinical Psychological Medicine 2005;15(3):168-70.
Wang 2005b {published data only}
  • Wang X, Yang J, Guo H. Clinical study of quetiapine and risperidone in the treatment of schizophrenia. Journal of Clinical Psychosomatic Diseases 2005;11(2):118-9.
Wang 2005c {published data only}
  • Wang X-F, Wang W-H, Wang J-C. Analysis of quetiapine in treatment of first-episode schizophrenia. Sichuan Mental Health 2005;18:235-6.
Wang 2005d {published data only}
  • Wang Y, Sun M, Shao X. A comparative study between quetiapine and clozapine in the treatment of schizophrenia. Heath Psychology Journal 2005;13(4):271-2.
Wang 2006a {published data only}
  • Wang D, Wang X. Comparative study of guetiapine and risperidone in the treatment of schizophrenia. Modern Medicine Health 2006;22(6):815-6.
Wang 2006b {published data only}
  • Wang J, Ran R. Effects of quetiapine vs clozapine on the quality of life in first-episode schizophrenics. Journal of Clinical Psychosomatic Disorders 2006;12(6):416-7.
Wang 2007 {published data only}
  • Wang C, Xu X, Huo X. A study of quetiapine and risperidone in treatment of chronic schizophrenia. Journal of Clinical Psychological Medicine 2007;17(4):165-6.
Wang 2007a {published data only}
  • Wang H, Sun D, Zhang Z, Gao C. A control study of quetiapine and risperidone in the treatment of children's schizophrenia. Journal of Clinical Psychological Medicine 2007;17(3):199-200.
Wang 2007b {published data only}
  • Wang Y, Chen T. Non-classical antipsychotic drugs for schizophrenia :cost minimization analysis on 3 schemes. China Pharmacy 2007;18(32):2487-8.
Wang 2008 {published data only}
  • Wang J, Wu H. A comparative study of social function in schizophrenia patients treated with seroquel or clozapine. Medical Journal of Chinese People's Health 2008;20(11):1137-8.
Wang 2008a {published data only}
  • Wang X, Song C. Comparative study of efficacy and safety of quetiapine and risperidone in the treatment of elderly schizophrenia. China Journal of Health Psychology 2008;16(12):1394-6.
Wang 2008b {published data only}
  • Wang Y, Li G, Li T. Comparison on the efficacy of quetiapine and risperidone in the treatment of the depressive symptom of schizophrenia. Tianjin Pharmacy 2008;20(2):33-6.
Wang 2008c {published data only}
  • Wang Y, Wang J. Effects of quetiapine on cognitive function in schizophrenia patients. China Practical Medicine 2008;3(18):61-2.
Wei 2006 {published data only}
  • Wei S. A randomized, double blind double dummy parallel controlled study in the female first-onset schizophrenia treated with aripiprazole and quetiapine. Nervous Diseases and Mental Health 2006;6(3):194-7.
Wei 2006c {published data only}
  • Wei S. A control study of quetiapine and clozapine in the treatment of eldly schizophrenia. Journal of Clinical Psychological Medicine 2006;16(1):43.
Weickert 2003 {published data only}
  • Weickert TW, Goldberg TE, Marenco S, Bigelow LB, Egan MF, Weinberger DR. Comparison of cognitive performances during a placebo period and an atypical antipsychotic treatment period in schizophrenia: critical examination of confounds. Neuropyschopharmacology 2003;28(8):1491-500.
Wen 2005 {published data only}
  • Wen S, Chen F. A control study of quetiapine and risperidone in the treatment of schizophrenia. Modern Medicine Health 2005;21(22):3089-90.
Wu 2005 {published data only}
  • Wu Y, Wang X. A control study of quetiapine and risperidone in the treatment of schizophrenia. Journal of Clinical Psychological Medicine 2005;15(2):106-7.
Xiang 2005 {published data only}
  • Xiang DF, Liu XL. Treatment of 31 cases of schizophrenia with quetiapine. Herald of Medicine 2005;24(1):40-2.
Xu 2002 {published data only}
  • Xu MQ, Peng MY. A study of Quetiapine in treatment of schizophrenia. Journal of Clinical Psychology Medicine 2002;12:227-8.
Xu 2003 {published data only}
  • Xu LZ, Ouyang JL, Gao SZ. Effects of domestic quetiapine vs clozapine in treatment of schizophrenia. Chinese Journal of New Drugs and Clinical Remedies 2003;7477(9):542-5.
Xu 2005 {published data only}
  • Xu XF, Zhang XB, Zhou CY, Dai XG. Comparison of efficacy and safety of seroquel and risperidone in the treatment of schizophrenia. Journal of Jiangsu Clinical Medicine 2005;9(1):20-2.
Xu 2006 {published data only}
  • Xu B. Comparative observation on the efect of quetiapine fumarate on chronic schizoprenia patients. China Tropical Medicine 2006;6(6):1032.
Yamashita 2005 {published data only}
  • Yamashita H, Mori K, Nagao M, Okamoto Y, Morinobu S, Yamawaki S. Influence of aging on the improvement of subjective sleep quality by atypical antipsychotic drugs in patients with schizophrenia: comparison of middle-aged and older adults. American Journal of Geriatric Psychiatry 2005;13(5):377-84.
Yang 2004 {published data only}
  • Yang FS, Yang YL, Zhang ZH. Control study on quetiapine and clozapine in treatment of refractory schizophrenia. Medical Journal of Chinese People Health 2004;16(1):12-3.
Yang 2005 {published data only}
  • Yang Q-P, Huang Y-P, Yang B-X. The effect of quetiapine and risperidone on the EEG of first-episode schizophrenic patients. Shandong Archives of Psychiatry 2005;18(3):159-60.
Yang 2005a {published data only}
  • Yang Q-P, Huang Y-P, Yang B-X. The effect of quetiapine and risperidone on the EEG of first-episode schizophrenic patients. Shandong Archives of Psychiatry 2005;18(3):159-60.
Yang 2006 {published data only}
  • Yang Y. Control study of quetiapine and clozapine in the treatment of refractory schizophrenia. Practical Journal of Cardiac Cerebral Pneumal and Vascular Disease 2006;14(4):276-7.
Yang 2006a {published data only}
  • Yang M, Mu X, Zhao A. A clinical study of quetiapine associated with clonazepam in the treatment of schizophrenia. Journal of Qiqihar Medical College 2006;27(9):1034-5.
Yang 2006b {published data only}
  • Yang C, Guo P, Guo H. Control study on using quetiapine to treat schizophrenic patients. China Practical Medicine 2006;1(1):24-6.
Yang 2007 {published data only}
  • Yang K. Comparative study between the effect of risperidone and quetiapine in first-episode schizophrenia. Medical Journal of Chinese People's Health 2007;19(3):203-4.
Yang 2007a {published data only}
  • Yang X, Wang Z, Lv Y, Shi Y. Comparative study of curative effects and influence on cognitive function of quetiapine and clozapine in schizophrenia. Journal of Clinical Psychosomatic Disorders 2007;13(1):29-30.
Yu 2003 {published data only}
  • Yu G, Liang S, He Z-G. Comparison of quetiapine and clozapine in treatment of schizophrenia. Journal of Clinical Psychiatry Medicine 2003;25:4-5.
Yu 2005 {published data only}
  • Yu H, Kong H. A control study of quetiapine and risperidone in the treatment of schizophrenia. Journal of Clinical Psychological Medicine 2005;15(6):362.
Yu 2006 {published data only}
  • Yu W, Liu H, Pan S. A control study of quetiapine and loxapine in the treatment of schizophrenia. Journal of Clinical Psychological Medicine 2006;16(5):298.
Yuan 2005 {published data only}
  • Yuan F-J, Gao M-Z, Liu X. A contrast observation of quetiapine and clozapine in affecting electroencephalogram. Journal of Practical Medical Techniques 2005;12(2B):482-4.
Zeng 2006 {published data only}
  • Zeng J. A control study of quetiapine and aripiprazole in the treatment of children's schizophrenia. Journal of Clinical Psychological Medicine 2006;16(6):367.
Zhang 2003 {published data only}
  • Zhang L, Wu Y, Guo C. A comparative study between quetiapine and risperidone in the treatment of schizophrenia. Health Psychology Journal 2003;11(4):262-3.
Zhang 2005 {published data only}
  • Zhang M, Zhang H-F, Gu W. A comparative study of quetiapine and clozapine in the treatment of schizophrenia. Shandong Archives of Psychiatry 2005;18(2):86-8.
Zhang 2005a {published data only}
  • Zhang H, Zhang M, Gu W. A comparative study of social function in schizophrenia patients treated with seroquel (quetiapine) or clozapine. Sichuan Mental Health 2005;18(2):91-3.
Zhang 2005b {published data only}
  • Zhang R-X, Cao Y-F. A comparative study of EKG changed by quetiapine and clozapine in the treatment of schizophrenia. Medical Journal of Chinese People Health 2005;17(6):290-1.
Zhang 2005c {published data only}
  • Zhang Y, Jiang Y, Zhao S. A comparative study of quetiapine combined with clomipramine in treatment of schizophrenia with obsessive-compulsive symptoms. Chinese Journal of Health Psychology 2005;13(4):260-2.
Zhang 2005d {published data only}
  • Zhang W, Ma J, Ma L. A control study of quetiapine and risperidone in the treatment of first-episode schizophrenia. Chinese Journal of Current Traditional and Western Medicine 2005;3(12):1088-9.
Zhang 2006 {published data only}
  • Zhang w, Ma J, Xu F. Comparison study on treatment of primary schizophrenia with quetiapine and chlorpromazine. Heilongjiang Medical Journal 2006;30(2):81-2.
Zhang 2006a {published data only}
  • Zhang Y, Zhou B. A control study of quetiapine and clozapine in the treatment of schizophrenia. Journal of Clinical Psychological Medicine 2006;16(5):300.
Zhang 2007 {published data only}
  • Zhang C. A control study of quetiapine and risperidone in the treatment of schizophrenia. Journal of Clinical Psychological Medicine 2007;17(3):197-8.
Zhang 2007a {published data only}
  • Zhang L. A comparative study of quetiapine and chlorpromazine in the treatment of schizophrenia. Modern Medicine Journal of China 2007;9(2):97-8.
Zhang 2009b {published data only}
  • Zhang B. Pilot Study to Evaluate the Efficacy and Safety of Quetiapine Fumarate Instant-Release (SeroquelIR) in Controlling Agitation and AggressiveSymptoms in the Acute Treatment of Patients With Schizophrenia. WHO trial registration 2009; Vol. 2.
Zhao 2004 {published data only}
  • Zhao F, Zhang Z, Li H. Control studies of quetiapine and risperidone in the treatment of schizophrenia. Journal of Clinical Psychosomatic Diseases 2004;10(1):25-6.
Zhao 2005 {published data only}
  • Zhao L, Li Y, Qi F. Control study of quetiapine and risperidone in treatment of schizophrenics. Heath Psychology Journal 2005;13(1):56, 79-80.
Zhao 2005a {published data only}
  • Zhao YH, Fang JH, Wang SH, An CG, Ma X, Li HX. A study of quetiapine and clozapine in treatment of schizophrenia. Journal of Clinical Psychology Medicine 2005;15:231-2.
Zhao 2007 {published data only}
  • Zhao L, Gong GQ. A study of low-dos equetiapine with sulpiride in the treatment of schizophrenia. Journal of Clinical Research 2007;24(7):1181-2.
Zheng 2007 {published data only}
  • Zheng J, Wang B, Fu A, Li P. A control study of quetiapine and clozapine in the treatment of schizophrenia. Medical Recapitulate 2007;13(23):1878-9.
Zhong 2006a {published data only}
  • Zhong Z-Y, Tao J, Wang X-L, Wu X-L, Zhang J-B. Effect of antipsychotic plus buflomedil hydrochlorde in ameliorating the negative symptoms of patients with schizophrenia. Zhongguo Linchuang Kangfu 2006;10(2):30-2.
Zhou 2003 {published data only}
  • Zhou P, Gong F, Fan C. A control of treating chronic schizophrenia with seroquel or clozapine. Jiangxi Medical Journal 2003;38(6):395-6.
Zhou 2003a {published data only}
  • Zhou R, Dai X. A comparative study of quetiapine and clozapine in the treatment of patients with schizophrenia. Shanghai Archives of Psychiatry 2003;15(4):215-7.
Zhou 2006 {published data only}
  • Zhou M. A study of quetiapine with sulpiride in the treatment of chronic schizophrenia. Journal of Clinical Psychological Medicine 2006;16(6):368.
Zhou 2007 {published data only}
  • Zhou B, Zhang Y. A control study of quetiapine and risperidone in the treatment of schizophrenia. Journal of Baotou Medical College 2007;23(3):261-2.
Zhu 2006 {published data only}
  • Zhu Q, Zhang S. A control study of quetiapine and clozapine in the treatment of female schizophrenia. Herald of Medicine 2006;25(8):792-3.
Zhu 2008 {published data only}
  • Zhu M, Pan D, Lu S. A control study of quetiapine and aripiprozole in the treatment of schizophrenia. Practical Clinical Journal of Integrated Traditional Chinese and Western Medicine 2008;8(1):9-10.

References to studies awaiting assessment

  1. References to studies included in this review
  2. References to studies excluded from this review
  3. References to studies awaiting assessment
  4. References to ongoing studies
  5. Additional references
  6. References to other published versions of this review
Gafoor 2005 {published data only}
  • Gafoor R, Landau S, Craig TKH, Elanjithara T, Power P, McGuire P. Efficacy and adverse effects of quetiapine versus risperidone in first-episode schizophrenia. Journal of Clinical Psychopharmacology 2010;30:600-6.
  • Gafoor R, Power P, Craig T, Kerwin R, McGuire P. A comparative study of quetiapine and risperidone in patients with first-episode psychosis. Journal of the European College of Neuropsychopharmacology 2005;15(Suppl 3):S509.

References to ongoing studies

  1. References to studies included in this review
  2. References to studies excluded from this review
  3. References to studies awaiting assessment
  4. References to ongoing studies
  5. Additional references
  6. References to other published versions of this review
Eli Lilly 2004b {published data only}
  • Eli Lilly, Company. Comparison of continuing olanzapine to switching to quetiapine in overweight or obese patients with schizophrenia and schizoaffective disorder. Eli Lilly and Company Clinical Trial Registry 2004. [8894]
Li 2009b {published data only}
  • Li HF. A 6-Week, Multicenter, Rater-Blind, Randomized,Risperidone-Controlled Study to Evaluate the Efficacy and Safety of Seroquel (Quetiapine Fumarate) in the Treatment of Chinese Han Patients With Schizophrenia. WHO registration 2009; Vol. 1.
Ratna 2003 {published data only}
  • Ratna L. A multi-centre, double-blind, randomised study to compare the safety tolerability and efficacy of quetiapine and risperidone in the treatment of schizophrenia in subjects with inadequate symptom control improved Response In Schizophrenia - IRIS. National Research Register 2003; Vol. 1.
Reynolds 2001 {published data only}
  • Reynolds C. A six month, rater blind comparison of quetiapine and risperidone in the treatment of tardive dyskinesia in patients with schizophrenia. National Research Register 2001; Vol. 3.

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  3. References to studies awaiting assessment
  4. References to ongoing studies
  5. Additional references
  6. References to other published versions of this review
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References to other published versions of this review

  1. References to studies included in this review
  2. References to studies excluded from this review
  3. References to studies awaiting assessment
  4. References to ongoing studies
  5. Additional references
  6. References to other published versions of this review
Komossa 2009
  • Komossa K, Rummel-Kluge C, Schmid F, Hunger H, Schwarz S, Srisurapanont M, Kissling W, Leucht S. Quetiapine versus other atypical antipsychotics for schizophrenia. Cochrane Database of Systematic Reviews 2010, Issue 1. [DOI: DOI:10.1002/14651858.CD006625.pub2.]
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Srisurapanont 2004