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Laparoscopically assisted radical vaginal hysterectomy versus radical abdominal hysterectomy for the treatment of early cervical cancer

  1. Ali Kucukmetin1,*,
  2. Ioannis Biliatis1,
  3. Raj Naik2,
  4. Andrew Bryant3

Editorial Group: Cochrane Gynaecological, Neuro-oncology and Orphan Cancer Group

Published Online: 1 OCT 2013

Assessed as up-to-date: 29 JUL 2013

DOI: 10.1002/14651858.CD006651.pub3

How to Cite

Kucukmetin A, Biliatis I, Naik R, Bryant A. Laparoscopically assisted radical vaginal hysterectomy versus radical abdominal hysterectomy for the treatment of early cervical cancer. Cochrane Database of Systematic Reviews 2013, Issue 10. Art. No.: CD006651. DOI: 10.1002/14651858.CD006651.pub3.

Author Information

  1. 1

    Northern Gynaecological Oncology Centre, Gynaecological Oncology, Gateshead, Tyne & Wear, UK

  2. 2

    Northern Gynaecological Oncology Centre, Gateshead, Tyne and Wear, UK

  3. 3

    Newcastle University, Institute of Health & Society, Newcastle upon Tyne, UK

*Ali Kucukmetin, Gynaecological Oncology, Northern Gynaecological Oncology Centre, Queen Elizabeth Hospital, Sheriff Hill, Gateshead, Tyne & Wear, NE9 6SX, UK.

Publication History

  1. Publication Status: Edited (no change to conclusions)
  2. Published Online: 1 OCT 2013



References to studies included in this review

  1. References to studies included in this review
  2. Additional references
Naik 2010 {published data only}
  • Naik R, Jackson KS, Lopes A, Cross P, Henry JA. Laparoscopic assisted radical vaginal hysterectomy versus radical abdominal hysterectomy - a randomised phase II trial: perioperative outcomes and surgicopathological measurements. BJOG: An International Journal of Obstetrics and Gynaecology 2010;117(6):746-51.

Additional references

  1. References to studies included in this review
  2. Additional references
Bergmark 2002
Canis 1992
  • Canis M, Maze G, Wattiez A, Pouly JL, Chapron C, Bruhat MA. Vaginally assisted laparoscopic radical hysterectomy. Journal of Gynaecological Surgery 1992;8:103-5.
Cantrell 2010
  • Cantrell LA, Mendivil A, Gehrig PA, Boggess JF. Survival outcomes for women undergoing type III robotic radical hysterectomy for cervical cancer: a 3-year experience. Gynecologic Oncology 2010;117:260-5.
Childers 1995
  • Childers JM, Nasseri A. Minimal access surgery in gynaecologic cancer: we can but should we?. Current Opinion in Obstetrics and Gynecology 1995;7:17-62.
Comerci 1998
CTCAE 2006
  • CTCAE. Common Terminology Criteria for Adverse Events. (accessed 6 September 2013); Vol. v3.0 (CTCAE).
Cuschieri 1999
Dargent 1987
  • Dargent D. A new future for Schauta's hysterectomy through pre-surgical retroperitoneal pelviscopy. European Journal of Gynaecological Oncocology 1987;8:292-5.
Dargent 2000
  • Dargent D, Martin X, Ansquer Y, Benchaim M, Mathevet P. Laparoscopic vaginal radical hysterectomy (LVRH) or celioschauta: evolution of the concept and outcomes in. Gynecologic Oncology 2000;76:230-84.
Dargent 2003
  • Dargent D. Laparoscopic assisted radical vaginal hysterectomy: evolution of a concept. CME Journal of Gynecology and Oncology 2003;20:102-9.
Deeks 2001
  • Deeks JJ, Altman DG, Bradburn MJ. Statistical methods for examining heterogeneity and combining results from several studies in meta-analysis. In: Egger M, Davey Smith G, Altman DG editor(s). Systematic Reviews in Health Care: Meta-Analysis in Context. 2nd Edition. London: BMJ Publication Group, 2001.
DerSimonian 1986
Di Saia 2002
  • Di Saia PJ, Creasman W. Invasive cervical cancer. In: Di Saia, Creasman WT editor(s). Clinical Gynecologic Oncology. St Louis, MO, USA: Mosby, 2002.
Eltabbakh 2000
  • Sant M, Aareleid T, Berrino F, Bielska Lasota M, Carli PM, et al. and the EUROCARE Working Group. EUROCARE-3: survival of cancer patients diagnosed 1990-94 - results and commentary. Annals of Oncology 2003;14 (Suppl 5):v61-v118.
Geisler 2010
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Hagen 2000
Hertel 2003
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Higgins 2003
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Jackson 2004
  • Jackson KS, Das N, Naik R, Lopes AD, Godfrey KA, Hatem MH, et al. Laparoscopically assisted radical vaginal hysterectomy vs. radical abdominal hysterectomy for cervical cancer: a match controlled study. Gynecologic Oncology 2004;95:655-61.
Johnson 2008
Kadar 1993
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Lopes 1995
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NICE 2010
  • National Institute for Health and Clinical Excellence (NICE). Laparoscopic radical hysterectomy for early stage cervical cancer. Interventional procedure guidance 338, 2010. (assessed 8 September 2013).
Obermair 2008
  • Obermair A, Gebski V, Frumovitz M, Soliman PT, Schmeler KM, Levenback C, et al. A phase III randomized clinical trial comparing laparoscopic or robotic radical hysterectomy with abdominal radical hysterectomy in patients with early stage cervical cancer. Journal of Minimally Invasive Gynecology 2008;15(5):584-8.
Pahisa 2010
  • Pahisa J, Martinez-Roman S, Torne A, Fuste P, Alonso I, Lejarcegui JA, et al. Comparative study of laparoscopically assisted radical vaginal hysterectomy and open Wertheim-Meigs in patients with early-stage cervical cancer: eleven years of experience. International Journal of Gynecological Cancer 2010;20:173-8.
Parmar 1998
Pecorelli 2009
Querleu 1993
Roy 2011
Sharma 2006
Spirtos 1996
  • Spirtos NM, Eisenkop SM, Schlaerth JB, Ballon SC. Laparoscopic radical hysterectomy with aortic and pelvic lymphadenectomy: surgical morbidity and intermediate follow-up. American Journal of Obstetrics and Gynaecology 1996;174:1763-8.
Yim 2011