Get access

Chemotherapy for children with medulloblastoma

  • Protocol
  • Intervention



This is a protocol for a Cochrane Review (Intervention). The objectives are as follows:

Primary objectives:
1. To determine the event-free survival (EFS) and overall survival (OS) in children with medulloblastoma receiving chemotherapy as a part of their treatment, as compared to children not receiving chemotherapy as part of their treatment.
2. To determine the EFS and OS in children with medulloblastoma receiving standard dose radiotherapy without chemotherapy, as compared to children receiving reduced dose radiotherapy with chemotherapy.

Secondary objectives:
1. To determine possible adverse effects of chemotherapy and radiotherapy, including long-term side effects.

2. To determine possible effects of treatment on the quality of life.