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Low molecular weight heparin for prevention of venous thromboembolism in patients with lower-leg immobilization

  1. Mark Testroote1,*,
  2. Willem AH Stigter2,
  3. Loes Janssen3,
  4. Heinrich MJ Janzing4

Editorial Group: Cochrane Vascular Group

Published Online: 25 APR 2014

Assessed as up-to-date: 3 JUN 2013

DOI: 10.1002/14651858.CD006681.pub3


How to Cite

Testroote M, Stigter WAH, Janssen L, Janzing HMJ. Low molecular weight heparin for prevention of venous thromboembolism in patients with lower-leg immobilization. Cochrane Database of Systematic Reviews 2014, Issue 4. Art. No.: CD006681. DOI: 10.1002/14651858.CD006681.pub3.

Author Information

  1. 1

    Maastricht University Medical Centre, Department of Surgery, Maastricht, Netherlands

  2. 2

    Viecuri Medical Centre of Northern Limburg, Department of Surgery and Orthopaedic Surgery, Venlo, Limburg, Netherlands

  3. 3

    Viecuri Medical Centre of Northern Limburg, Department of Clinical Epidemiology, Venlo, Netherlands

  4. 4

    VieCuri Medical Centre of Northern Limburg, Department of Surgery, Venlo, Limburg, Netherlands

*Mark Testroote, Department of Surgery, Maastricht University Medical Centre, P. Debyelaan 25, Maastricht, 6202 AZ, Netherlands. marktestroote@yahoo.com. marktestroote@gmail.com.

Publication History

  1. Publication Status: New search for studies and content updated (no change to conclusions)
  2. Published Online: 25 APR 2014

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[Figure 1]
Figure 1. Study flow diagram.
[Analysis 1.1]
Analysis 1.1. Comparison 1 Low molecular weight heparin versus no prophylaxis/placebo, Outcome 1 DVT: irrespective of type of plaster, whether operated or not.
[Analysis 1.2]
Analysis 1.2. Comparison 1 Low molecular weight heparin versus no prophylaxis/placebo, Outcome 2 DVT: in below-knee cast, whether operated or not.
[Analysis 1.3]
Analysis 1.3. Comparison 1 Low molecular weight heparin versus no prophylaxis/placebo, Outcome 3 PE.
[Analysis 1.4]
Analysis 1.4. Comparison 1 Low molecular weight heparin versus no prophylaxis/placebo, Outcome 4 DVT: only non-operated patients.
[Analysis 1.5]
Analysis 1.5. Comparison 1 Low molecular weight heparin versus no prophylaxis/placebo, Outcome 5 DVT: operated patients.
[Analysis 1.6]
Analysis 1.6. Comparison 1 Low molecular weight heparin versus no prophylaxis/placebo, Outcome 6 DVT: fractures.
[Analysis 1.7]
Analysis 1.7. Comparison 1 Low molecular weight heparin versus no prophylaxis/placebo, Outcome 7 DVT: soft-tissue injuries.
[Analysis 1.8]
Analysis 1.8. Comparison 1 Low molecular weight heparin versus no prophylaxis/placebo, Outcome 8 DVT: distal segment.
[Analysis 1.9]
Analysis 1.9. Comparison 1 Low molecular weight heparin versus no prophylaxis/placebo, Outcome 9 DVT: proximal segment.
[Analysis 1.10]
Analysis 1.10. Comparison 1 Low molecular weight heparin versus no prophylaxis/placebo, Outcome 10 Symptomatic VTE.