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Antibiotic therapy for Shigella dysentery

  1. Prince RH Christopher1,*,
  2. Kirubah V David2,
  3. Sushil M John2,
  4. Venkatesan Sankarapandian2

Editorial Group: Cochrane Infectious Diseases Group

Published Online: 4 AUG 2010

Assessed as up-to-date: 17 JUL 2009

DOI: 10.1002/14651858.CD006784.pub4


How to Cite

Christopher PRH, David KV, John SM, Sankarapandian V. Antibiotic therapy for Shigella dysentery. Cochrane Database of Systematic Reviews 2010, Issue 8. Art. No.: CD006784. DOI: 10.1002/14651858.CD006784.pub4.

Author Information

  1. 1

    Christian Medical College, Family Medicine, Vellore, Tamilnadu, India

  2. 2

    Christian Medical College, LCECU, Vellore, Tamil Nadu, India

*Prince RH Christopher, Family Medicine, Christian Medical College, Vellore, Tamilnadu, 632004, India. prince.christopher@gmail.com.

Publication History

  1. Publication Status: Edited (no change to conclusions)
  2. Published Online: 4 AUG 2010

SEARCH

[Figure 1]
Figure 1. Methodological quality summary: review authors' judgments about each methodological quality item for each included study.
[Figure 2]
Figure 2. Methodological quality graph: review authors' judgments about each methodological quality item presented as percentages across all included studies.
[Analysis 1.1]
Analysis 1.1. Comparison 1 Antibiotic versus no drug or placebo, Outcome 1 Diarrhoea on follow up.
[Analysis 1.2]
Analysis 1.2. Comparison 1 Antibiotic versus no drug or placebo, Outcome 2 Time to cessation of fever (in days).
[Analysis 1.3]
Analysis 1.3. Comparison 1 Antibiotic versus no drug or placebo, Outcome 3 Time to cessation of diarrhoea (in days).
[Analysis 1.4]
Analysis 1.4. Comparison 1 Antibiotic versus no drug or placebo, Outcome 4 Time to cessation of blood in stools (in days).
[Analysis 1.5]
Analysis 1.5. Comparison 1 Antibiotic versus no drug or placebo, Outcome 5 Other adverse events.
[Analysis 2.1]
Analysis 2.1. Comparison 2 Fluoroquinolones versus beta-lactams, Outcome 1 Diarrhoea on follow up.
[Analysis 2.2]
Analysis 2.2. Comparison 2 Fluoroquinolones versus beta-lactams, Outcome 2 Fever at follow up.
[Analysis 2.3]
Analysis 2.3. Comparison 2 Fluoroquinolones versus beta-lactams, Outcome 3 Relapse.
[Analysis 2.4]
Analysis 2.4. Comparison 2 Fluoroquinolones versus beta-lactams, Outcome 4 Bacteriological failure.
[Analysis 2.5]
Analysis 2.5. Comparison 2 Fluoroquinolones versus beta-lactams, Outcome 5 Development of severe complications.
[Analysis 2.6]
Analysis 2.6. Comparison 2 Fluoroquinolones versus beta-lactams, Outcome 6 Serious adverse events.
[Analysis 2.7]
Analysis 2.7. Comparison 2 Fluoroquinolones versus beta-lactams, Outcome 7 Adverse events leading to discontinuation of treatment.
[Analysis 2.8]
Analysis 2.8. Comparison 2 Fluoroquinolones versus beta-lactams, Outcome 8 Other adverse events.
[Analysis 3.1]
Analysis 3.1. Comparison 3 Fluoroquinolones versus macrolides, Outcome 1 Diarrhoea on follow up.
[Analysis 3.2]
Analysis 3.2. Comparison 3 Fluoroquinolones versus macrolides, Outcome 2 Fever at follow up.
[Analysis 3.3]
Analysis 3.3. Comparison 3 Fluoroquinolones versus macrolides, Outcome 3 Time to cessation of blood in stools.
[Analysis 3.4]
Analysis 3.4. Comparison 3 Fluoroquinolones versus macrolides, Outcome 4 Bacteriological failure.
[Analysis 3.5]
Analysis 3.5. Comparison 3 Fluoroquinolones versus macrolides, Outcome 5 Other adverse events.
[Analysis 4.1]
Analysis 4.1. Comparison 4 Cotrimoxazole versus beta-lactams, Outcome 1 Diarrhoea on follow up.
[Analysis 4.2]
Analysis 4.2. Comparison 4 Cotrimoxazole versus beta-lactams, Outcome 2 Bacteriological failure.
[Analysis 4.3]
Analysis 4.3. Comparison 4 Cotrimoxazole versus beta-lactams, Outcome 3 Time to cessation of diarrhoea (hours).
[Analysis 4.4]
Analysis 4.4. Comparison 4 Cotrimoxazole versus beta-lactams, Outcome 4 Time to cessation of fever (hours).
[Analysis 4.5]
Analysis 4.5. Comparison 4 Cotrimoxazole versus beta-lactams, Outcome 5 Time to cessation of visible blood in stools.
[Analysis 4.6]
Analysis 4.6. Comparison 4 Cotrimoxazole versus beta-lactams, Outcome 6 Other adverse events.
[Analysis 5.1]
Analysis 5.1. Comparison 5 Cotrimoxazole versus fluoroquinolones (norfloxacin), Outcome 1 Bacteriological failure.
[Analysis 5.2]
Analysis 5.2. Comparison 5 Cotrimoxazole versus fluoroquinolones (norfloxacin), Outcome 2 Other adverse events.
[Analysis 6.1]
Analysis 6.1. Comparison 6 Cotrimoxazole versus furazolidone, Outcome 1 Diarrhoea on follow up.
[Analysis 7.1]
Analysis 7.1. Comparison 7 Oral gentamicin versus nalidixic acid, Outcome 1 Diarrhoea at follow up.
[Analysis 7.2]
Analysis 7.2. Comparison 7 Oral gentamicin versus nalidixic acid, Outcome 2 Fever at follow up.
[Analysis 7.3]
Analysis 7.3. Comparison 7 Oral gentamicin versus nalidixic acid, Outcome 3 Bacteriological relapse.
[Analysis 7.4]
Analysis 7.4. Comparison 7 Oral gentamicin versus nalidixic acid, Outcome 4 Bacteriological failure.
[Analysis 8.1]
Analysis 8.1. Comparison 8 Sulphonamides versus tetracycline, Outcome 1 Diarrhoea at follow up.
[Analysis 8.2]
Analysis 8.2. Comparison 8 Sulphonamides versus tetracycline, Outcome 2 Bacteriological failure.