Intervention Review

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Granulocyte-colony stimulating factors as adjunctive therapy for diabetic foot infections

  1. Mario Cruciani1,*,
  2. Benjamin A Lipsky2,
  3. Carlo Mengoli3,
  4. Fausto de Lalla4

Editorial Group: Cochrane Wounds Group

Published Online: 17 AUG 2013

Assessed as up-to-date: 14 MAR 2013

DOI: 10.1002/14651858.CD006810.pub3


How to Cite

Cruciani M, Lipsky BA, Mengoli C, de Lalla F. Granulocyte-colony stimulating factors as adjunctive therapy for diabetic foot infections. Cochrane Database of Systematic Reviews 2013, Issue 8. Art. No.: CD006810. DOI: 10.1002/14651858.CD006810.pub3.

Author Information

  1. 1

    ULSS 20 Verona, Center of Community Medicine and Infectious Diseases Service, Verona, Italy

  2. 2

    University of Washington, Medicine, Seattle, Washington, USA

  3. 3

    Università di Padova, Department of Histology, Microbiology and Medical Biotechnology, PADOVA, Italy

  4. 4

    Ospedale san Bortolo, Department of Infectious Diseases, Vicenza, Italy

*Mario Cruciani, Center of Community Medicine and Infectious Diseases Service, ULSS 20 Verona, Via Germania, 20, Verona, 37135, Italy. crucianimario@virgilio.it.

Publication History

  1. Publication Status: New search for studies and content updated (no change to conclusions)
  2. Published Online: 17 AUG 2013

SEARCH

[Figure 1]
Figure 1. Methodological quality graph: review authors' judgements about each methodological quality item presented as percentages across all included studies.
[Figure 2]
Figure 2. Methodological quality summary: review authors' judgements about each methodological quality item for each included study.
[Figure 3]
Figure 3. Forest plot of comparison: 3 Need for surgery, outcome: 3.1 Overall surgical intervention.
[Figure 4]
Figure 4. Forest plot of comparison: 3 Need for surgery, outcome: 3.2 Amputation.
[Analysis 1.1]
Analysis 1.1. Comparison 1 Infection status, Outcome 1 Resolution of infection.
[Analysis 1.2]
Analysis 1.2. Comparison 1 Infection status, Outcome 2 Improvement.
[Analysis 2.1]
Analysis 2.1. Comparison 2 Healing of wounds, Outcome 1 Healing of wounds.
[Analysis 3.1]
Analysis 3.1. Comparison 3 Need for surgery, Outcome 1 Overall surgical intervention.
[Analysis 3.2]
Analysis 3.2. Comparison 3 Need for surgery, Outcome 2 Amputation.
[Analysis 4.1]
Analysis 4.1. Comparison 4 Adverse events, Outcome 1 Occurrence of side effects.
[Analysis 5.1]
Analysis 5.1. Comparison 5 Duration of antibiotic therapy provided, Outcome 1 Days with systemic antibiotics.
[Analysis 6.1]
Analysis 6.1. Comparison 6 Duration of hospitalisation needed, Outcome 1 Days of hospital stay.
[Analysis 7.1]
Analysis 7.1. Comparison 7 Total leucocyte count, Outcome 1 White blood cell count.