Intervention Review

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Heliox for croup in children

  1. Irene Moraa1,*,
  2. Nancy Sturman2,
  3. Treasure McGuire3,
  4. Mieke L van Driel2,4,5

Editorial Group: Cochrane Acute Respiratory Infections Group

Published Online: 7 DEC 2013

Assessed as up-to-date: 12 NOV 2013

DOI: 10.1002/14651858.CD006822.pub4


How to Cite

Moraa I, Sturman N, McGuire T, van Driel ML. Heliox for croup in children. Cochrane Database of Systematic Reviews 2013, Issue 12. Art. No.: CD006822. DOI: 10.1002/14651858.CD006822.pub4.

Author Information

  1. 1

    Pharmacy Australia Centre of Excellence, School of Pharmacy, Woolloongabba, Australia

  2. 2

    The University of Queensland, Discipline of General Practice, School of Medicine, Brisbane, Queensland, Australia

  3. 3

    Bond University, Faculty of Health Sciences and Medicine, Gold Coast, Queensland, Australia

  4. 4

    Bond University, Centre for Research in Evidence-Based Practice, Gold Coast, QLD, Australia

  5. 5

    Ghent University, Department of General Practice and Primary Health Care, Ghent, Belgium

*Irene Moraa, School of Pharmacy, Pharmacy Australia Centre of Excellence, 20 Cornwall Street, Woolloongabba, Australia. imoraa@yahoo.com.

Publication History

  1. Publication Status: New search for studies and content updated (conclusions changed)
  2. Published Online: 7 DEC 2013

SEARCH

[Figure 1]
Figure 1. Flow diagram of study selection
[Figure 2]
Figure 2. Methodological quality graph: review authors' judgements about each methodological quality item presented as percentages across all included studies.
[Analysis 1.1]
Analysis 1.1. Comparison 1 Heliox versus oxygen 30%, Outcome 1 Mean change in croup score.
[Analysis 1.2]
Analysis 1.2. Comparison 1 Heliox versus oxygen 30%, Outcome 2 Westley croup score at 20 min.
[Analysis 1.3]
Analysis 1.3. Comparison 1 Heliox versus oxygen 30%, Outcome 3 Heart rate at 20 min.
[Analysis 1.4]
Analysis 1.4. Comparison 1 Heliox versus oxygen 30%, Outcome 4 Respiratory rate at 20 min.
[Analysis 1.5]
Analysis 1.5. Comparison 1 Heliox versus oxygen 30%, Outcome 5 Oxygen saturation at 20 min.
[Analysis 2.1]
Analysis 2.1. Comparison 2 Heliox versus placebo or no treatment, Outcome 1 Need for rescue adrenaline.
[Analysis 2.2]
Analysis 2.2. Comparison 2 Heliox versus placebo or no treatment, Outcome 2 Taussig croup score at 60 min.
[Analysis 2.3]
Analysis 2.3. Comparison 2 Heliox versus placebo or no treatment, Outcome 3 Taussig croup score at 120 min.
[Analysis 2.4]
Analysis 2.4. Comparison 2 Heliox versus placebo or no treatment, Outcome 4 Respiratory rate at 60 min.
[Analysis 2.5]
Analysis 2.5. Comparison 2 Heliox versus placebo or no treatment, Outcome 5 Respiratory rate at 120 min.
[Analysis 2.6]
Analysis 2.6. Comparison 2 Heliox versus placebo or no treatment, Outcome 6 Number of children admitted.
[Analysis 2.7]
Analysis 2.7. Comparison 2 Heliox versus placebo or no treatment, Outcome 7 Number of re-presentations to ED.