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Platinum vs non-platinum chemotherapy regimes for small cell lung cancer

  • Protocol
  • Intervention


  • I Amarasena,

  • J Walters,

  • R Wood-Baker,

  • K Fong

Isuru Amarasena, Medical Student, School of Medicine, University of Tasmania, 43 Collins Street, Hobart, Tasmania, 7000, AUSTRALIA.


This is the protocol for a review and there is no abstract. The objectives are as follows:

To determine the effectiveness of platinum chemotherapeutic agents compared with non-platinum chemotherapeutic agents in the treatment of small cell lung cancer with respect to survival, tumour response, toxicity and quality of life, by undertaking the following comparisons:
a)Platinum agents versus other chemotherapeutic agents [P v A]
b)Platinum agents combined with other chemotherapy agents versus the same chemotherapy regime without the platinum agents [(P+A) v A]
c)Platinum agents combined with other chemotherapy agents versus any other chemotherapy regimes without platinum agents [(P+A) v B]
Where P = platinum chemotherapy agents, A = non-platinum chemotherapy regimes, B = non-platinum chemotherapy regimes (different from A)