Intervention Review

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Interventions for the restorative care of amelogenesis imperfecta in children and adolescents

  1. Mayssoon Dashash1,*,
  2. C Albert Yeung2,
  3. Issam Jamous3,
  4. Anthony Blinkhorn4

Editorial Group: Cochrane Oral Health Group

Published Online: 6 JUN 2013

Assessed as up-to-date: 30 APR 2013

DOI: 10.1002/14651858.CD007157.pub2


How to Cite

Dashash M, Yeung CA, Jamous I, Blinkhorn A. Interventions for the restorative care of amelogenesis imperfecta in children and adolescents. Cochrane Database of Systematic Reviews 2013, Issue 6. Art. No.: CD007157. DOI: 10.1002/14651858.CD007157.pub2.

Author Information

  1. 1

    Faculty of Dentistry, University of Damascus, Department of Paediatric Dentistry, Damascus, Syrian Arab Republic

  2. 2

    NHS Lanarkshire, Department of Public Health, Bothwell, UK

  3. 3

    Dental School, University of Damascus, Department of Fixed Prosthodontics, Mazzeh Jabal, Damascus, Syrian Arab Republic

  4. 4

    Faculty of Dentistry, The University of Sydney, Population Oral Health, Westmead, Australia

*Mayssoon Dashash, Department of Paediatric Dentistry, Faculty of Dentistry, University of Damascus, Mezza Autustrad, Behind Razzi Hospital, Doctors' Building, Damascus, Syrian Arab Republic. mdashash@yahoo.com.

Publication History

  1. Publication Status: Stable (no update expected for reasons given in 'What's new')
  2. Published Online: 6 JUN 2013

SEARCH

 
Characteristics of excluded studies [ordered by study ID]

StudyReason for exclusion

Baratieri 2003Study included teeth affected by non-carious lesions rather than amelogenesis imperfecta (AI)

Cheng 2004Study included teeth affected by non-carious lesions rather than AI

Coll 1991Study included incisors with enamel surface defects rather than AI

Deliperi 2006Study included teeth affected by non-carious lesions rather than AI

Folwaczny 2001Study included teeth affected by non-carious lesions rather than AI

Fron 2011Study included teeth affected by non-carious lesions rather than AI

Gladys 1998Study included teeth affected by non-carious lesions rather than AI

Kim 2011Study included teeth affected by molar-incisor hypomineralisation (MIH) only

Kramer 2005Study included teeth affected by non-carious lesions rather than AI

Lygidakis 2009Not a randomised controlled trial, MIH

Markovic 2010Case series

Marta 2000Study included teeth affected by non-carious lesions rather than AI

Peumans 2005Study included teeth affected by non-carious lesions rather than AI

Peumans 2010Study included teeth affected by non-carious lesions rather than AI

Sönmez 2009Not a randomised controlled trial, different outcomes

Van Landuyt 2008Study included teeth affected by non-carious lesions rather than AI

Van Meerbeek 2005Study included teeth affected by non-carious lesions rather than AI

Walls 1988No AI, no controls

Zagdwon 2003Study includes both AI and participants with other severe enamel defects. Further correspondence with study authors needed to identify the results of the five patients who specifically suffered from AI

 
Characteristics of ongoing studies [ordered by study ID]
ISRCTN70438627

Trial name or titleEarly restorative crown therapy in children and adolescents with amelogenesis imperfecta (AI): a prospective double-blind randomised controlled trial

MethodsSingle centre double-blind randomised controlled trial, split-mouth design

ParticipantsSetting: Centre for Oral Rehabilitation, special care department for children and adolescents, Falun, Dalarna, Sweden

Inclusion criteria: Children and adolescents with AI, 6 to 25 years of age, referred for oral rehabilitation

Exclusion criteria: AI in combination with syndromes including mental retardation

Randomised: 28 (15 boys and 13 girls). 12 to 23 years of age, all of Caucasian origin

AI type was recorded as either hypoplastic type (14) or hypomineralised or hypomaturation type (14)

InterventionsTreatment with Procera crown therapy with Zirconia inner coping cemented with Rely X ARC cement or E-MAX crowns with Zirconia inner coping cemented with Rely X ARC cement

Follow-up examinations: 1 month, 1 year and 2 years

OutcomesPrimary outcomes

  • Quality of restorations after 1 month, 1 year and a 2-year observation period according to Ryge & De Vinzenci (1983)
  • Sensitivity, measured using the Visual Analogue Scale (VAS) score (0 = no pain, 10 = unbearable pain) at baseline, 1 month and 2 years


Secondary outcomes

  • Dental caries according to Amarante et al (1998)
  • Gingivitis and periodontitis according to Nyman and Linde (2003)
  • Apical status according to Örstavik (1986)

Starting date1 January 2009

Contact informationProfessor Goran Dahllöf

Karolinska Institutet
Department of Dental Medicine
Division of Orthodontics and Pediatric Dentistry
POB 4064

Huddinge

SE-14104

Sweden

FundingCentre for Clinical Research, Public Dental Service Dalarna (Sweden)

Notes1-year results were published as an abstract in 2012