Intervention Protocol

Blood pressure lowering efficacy of calcium-channel blockers as second-line therapy for primary hypertension

  1. Jenny MH Chen*,
  2. Balraj S Heran,
  3. Marco I Perez,
  4. James M Wright

Editorial Group: Cochrane Hypertension Group

Published Online: 23 APR 2008

DOI: 10.1002/14651858.CD007186


How to Cite

Chen JMH, Heran BS, Perez MI, Wright JM. Blood pressure lowering efficacy of calcium-channel blockers as second-line therapy for primary hypertension (Protocol). Cochrane Database of Systematic Reviews 2008, Issue 2. Art. No.: CD007186. DOI: 10.1002/14651858.CD007186.

Author Information

  1. University of British Columbia, Department of Anesthesiology, Pharmacology and Therapeutics, Vancouver, BC, Canada

*Jenny MH Chen, Department of Anesthesiology, Pharmacology and Therapeutics, University of British Columbia, 2176 Health Sciences Mall, Vancouver, BC, V6T 1Z3, Canada. koko_jesse@hotmail.com.

Publication History

  1. Publication Status: Edited (no change to conclusions)
  2. Published Online: 23 APR 2008

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Abstract

  1. Top of page
  2. Abstract

This is the protocol for a review and there is no abstract. The objectives are as follows:

Primary objective: To quantify the additional reduction in systolic blood pressure (SBP) and diastolic blood pressure (DBP) of calcium-channel blocker (CCB) therapy as a second-line drug in hypertensive patients.

Secondary objectives:
1. To determine the effects of second-line CCB on variability of blood pressure.
2. To determine the effects of second-line CCB on pulse pressure.
3. To quantify the effect of second-line CCB on heart rate.
4. To quantify the effect of second-line CCB on withdrawals due to adverse effects.