Intervention Review

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Interventions for smoking cessation and reduction in individuals with schizophrenia

  1. Daniel T Tsoi1,*,
  2. Mamta Porwal2,
  3. Angela C Webster3

Editorial Group: Cochrane Tobacco Addiction Group

Published Online: 28 FEB 2013

Assessed as up-to-date: 10 JAN 2013

DOI: 10.1002/14651858.CD007253.pub3

How to Cite

Tsoi DT, Porwal M, Webster AC. Interventions for smoking cessation and reduction in individuals with schizophrenia. Cochrane Database of Systematic Reviews 2013, Issue 2. Art. No.: CD007253. DOI: 10.1002/14651858.CD007253.pub3.

Author Information

  1. 1

    Nottinghamshire Healthcare NHS Trust, Nottingham, UK

  2. 2

    Cancer Council NSW, Woolloomooloo, NSW, Australia

  3. 3

    The University of Sydney, Sydney School of Public Health, Sydney, NSW, Australia

*Daniel T Tsoi, Nottinghamshire Healthcare NHS Trust, Institute of Mental Health, Jubilee Campus, University of Nottingham, Wollaton Road, Nottingham, NG8 1BB, UK. daniel.tsoi@nottshc.nhs.uk. t.tsoi@sheffield.ac.uk.

Publication History

  1. Publication Status: New search for studies and content updated (no change to conclusions)
  2. Published Online: 28 FEB 2013

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References

References to studies included in this review

  1. References to studies included in this review
  2. References to studies excluded from this review
  3. References to studies awaiting assessment
  4. References to ongoing studies
  5. Additional references
  6. References to other published versions of this review
^Horst 2005 {published data only}
  • Horst W, Klein MW, Williams D, Werder SF. Extended use of nicotine replacement therapy to maintain smoking cessation in persons with schizophrenia. Neuropsychiatric Disease and Treatment 2005;1(4):349-55.
*Baker 2006 {published and unpublished data}
  • Baker A, Richmond R, Haile M, Lewin TJ, Carr VJ, Taylor RL, et al. A randomized controlled trial of a smoking cessation intervention among people with a psychotic disorder. American Journal of Psychiatry 2006;163:1934-42.
  • Baker A, Richmond R, Haile M, Lewin TJ, Carr VJ, Taylor RL, et al. Characteristics of smokers with a psychotic disorder and implications for smoking interventions. Psychiatry Research 2007;150:141-152.
  • Baker A, Richmond R, Lewin TJ, Kay-Lambkin F. Cigarette smoking and psychosis: naturalistic follow up 4 years after an intervention trial. Australian and New Zealand Journal of Psychiatry 2010; Vol. 44, issue 4:342-50.
  • Richmond RL, Baker A, Haile M, Carr V, Lewin T, Wilhelm K, et al. Intervention for tobacco dependence among people with a psychotic illness: RCT with one year outcome. Nicotine & Tobacco Research 2005;7(4):681.
*Chen 2012 {published data only}
  • Chen H-K, Lan T-H, Wu B-J. A double-blind randomized clinical trial of different doses of transdermal nicotine patch for smoking reduction and cessation in long-term hospitalised schizophrenic patients. European Archives of Psychiatry and Clinical Neuroscience 2012;epub:doi: 10.1007/s00406-012-0338-3.
*Evins 2001 {published and unpublished data}
  • Evins A, Cather C, Goff DC, Rigotti NA. Increased smoking cessation and reduction: Two years following a smoking cessation trial in patients with schizophrenia. Conference Abstract of Society for Research on Nicotine and Tobacco 9th Annual Meeting: New Orleans, Louisiana, USA. 2003.
  • Evins A, Mays VK, Rigotti NA, Tisdale T, Cather C, Goff DC. A pilot trial of bupropion added to cognitive behavioral therapy for smoking cessation in schizophrenia. Nicotine & Tobacco Research 2001;3(4):397-403.
  • Evins AE, Cather C, Rigotti NA, Freudenreich O, Henderson DC, Olm-Shipman CM, et al. Two-year follow-up of a smoking cessation trial in patients with schizophrenia: increased rates of smoking cessation and reduction. Journal of Clinical Psychiatry 2004;65(3):307-11.
  • Evins AE, Mays VK, Rigotti NA, Tisdale T, Daigle A, Goff DC. Reduction In tobacco use in schizophrenia with bupropion SR and Cognitive Behavioral Therapy. Conference abstract of Society for Research on Nicotine and Tobacco 6th Annual Meeting: Arlington, Virginia, USA. 2000.
*Evins 2005 {published and unpublished data}
  • Evins A, Cather C, Deckersbach T, Freudenreich O, Culhane MA, Olm-Shipman CM, et al. A double-blind placebo-controlled trial of bupropion Sustained-Release for smoking cessation in schizophrenia. Journal of Clinical Psychopharmacology 2005;25(3):218-25.
  • Evins A, Deckersbach T, Cather C, Freudenreich O, Culhane MA, Henderson DC, et al. Independent effects of tobacco abstinence and bupropion on cognitive function in schizophrenia. Journal of Clinical Psychiatry 2005;66(9):1184-90.
  • Evins AE, Cather C, Culhane M, Freudenreich O, Rigotti NA, Goff DC. Smoking cessation in schizophrenia: A double blind placebo controlled trial of bupropion SR added to cognitive behavioral therapy. Biological Psychiatry 2004;55:226S.
  • Evins AE, Cather C, Goff DC, Olm-Shipman C, Rigotti NA. A placebo controlled trial of bupropion SR for smoking cessation in schizophrenia (POS3-49). Conference abstract of Society for Research on Nicotine and Tobacco 9th Annual Meeting: New Orleans, Louisiana, USA. 2003.
  • Evins EA, Goff DC, Shipman CO, Rigotti NA, Cather C. A controlled trial of bupropion SR for smoking cessation in patients with schizophrenia. Conference abstract of 156th Annual Meeting of the American Psychiatric Association: San Francisco, USA. 2003.
*Evins 2007 {published and unpublished data}
  • Evins A, Cather C, Culhane MA, Birnbaum A, Horowitz J, Hsieh E, et al. A 12-week double-blind, placebo-controlled study of bupropion SR added to high-dose dual nicotine replacement therapy for smoking cessation or reduction in schizophrenia. Journal of Clinical Psychopharmacology 2007;27(4):380-6.
  • Evins AE, Cather C, Culhane M, Birnbaum AS, Horowitz J, Hsieh E, et al. A placebo-controlled study of bupropion SR added to high dose nicotine replacement therapy for smoking cessation or reduction in schizophrenia (POS2-104). Conference abstract of Society for Research on Nicotine and Tobacco 12th Annual Meeting: Orlando, Florida, USA. 2006.
*Gallagher 2007 {published and unpublished data}
  • Gallagher SM, Penn PE, Schindler E. Smoking cessation in persons with schizophrenia and other serious mental illness (PA1-5). Conference abstract of Society for Research on Nicotine and Tobacco 12th Annual Meeting: Orlando, Florida, USA. 2006.
  • Gallagher SM, Penn PE, Schindler E, Layne W. A comparison of smoking cessation treatments for persons with schizophrenia and other serious mental illnesses. Journal of Psychoactive Drugs 2007;39(4):487-97.
*George 2000 {published data only}
  • George TP, Hitsman B, Papandonatos GD, Sacco KA, Vessicchio JC, Dudas M, et al. Predictors of smoking cessation in schizophrenia: Analysis of data from three sequential controlled clinical trials. Neuropsychopharmacology 2004;29 Suppl 1:S103.
  • George TP, Ziedonis DM, Feingold A, Pepper W, Satterburg CA, Winkel J, et al. Nicotine transdermal patch and atypical antipsychotic medications for smoking cessation in schizophrenia. American Journal of Psychiatry 2000;157:1835-42.
  • Sacco KA, Hitsman B, Papandonatos GD, Vessicchio JC, Dudas MM, Termine A, et al. Predictors of smoking cessation in schizophrenia: analysis of data from three sequential controlled clinical trials (PA5-3). Conference abstract of the Society for Research on Nicotine and Tobacco 10th Annual Meeting: Phoenix, Arizona, USA. 2004.
*George 2002 {published data only}
  • George TP, Hitsman B, Papandonatos GD, Sacco KA, Vessicchio JC, Dudas M, et al. Predictors of smoking cessation in schizophrenia: Analysis of data from three sequential controlled clinical trials. Neuropsychopharmacology 2004;29 Suppl 1:S103.
  • George TP, Vessicchio JC, Termine A, Bregartner TA, Feingold A, Rounsaville BJ, et al. A placebo controlled trial of bupropion for smoking cessation in schizophrenia. Biological Psychiatry 2002;52(1):53-61.
  • Sacco KA, Hitsman B, Papandonatos GD, Vessicchio JC, Dudas MM, Termine A, et al. Predictors of smoking cessation in schizophrenia: analysis of data from three sequential controlled clinical trials (PA5-3). Conference abstract of the Society for Research on Nicotine and Tobacco 10th Annual Meeting: Phoenix, Arizona, USA. 2004.
  • Vessicchio JC, Termine A, Bregartner TA, George TP. Bupropion versus placebo for smoking cessation in schizophrenia. Conference abstract of the College on Problems of Drug Dependence 64th Anuual Scientific Meeting: Quebec, Canada. 2002.
*George 2008 {published data only}
  • George TP, Hitsman B, Papandonatos GD, Sacco KA, Vessicchio JC, Dudas M, et al. Predictors of smoking cessation in schizophrenia: Analysis of data from three sequential controlled clinical trials. Neuropsychopharmacology 2004;29 Suppl. 1:S103.
  • George TP, Vessicchio J, Allen T, Weinberger A, Sacco KA. A randomized, double-blind, placebo-controlled trial of sustained-release bupropion combined with transdermal nicotine patch for smoking cessation in schizophrenia: Neuropsychological predictors of treatment outcome. Neuropsychopharmacology 2006;31 Suppl. 1:S254-5.
  • George TP, Vessicchio JC, Sacco KA, Weinberger AH, Dudas MM, Allen TM, et al. A placebo-controlled trial of bupropion combined with nicotine patch for smoking cessation in schizophrenia. Biological Psychiatry 2008;63:1092-6.
  • George TP, Vessicchio JC, Weinberger AH, Sacco KA. Sustained-release bupropion combined with transdermal nicotine patch for smoking cessation in schizophrenia (SYM11C). Conference abstract of the Society for Research on Nicotine and Tobacco 13th Annual Meeting: Austin, Texas, USA. 2007.
  • Sacco KA, Hitsman B, Papandonatos GD, Vessicchio JC, Dudas MM, Termine A, et al. Predictors of smoking cessation in schizophrenia: analysis of data from three sequential controlled clinical trials (PA5-3). Conference abstract of the Society for Research on Nicotine and Tobacco 10th Annual Meeting: Phoenix, Arizona, USA. 2004.
*Li 2009 {published and unpublished data}
  • Li Jun, Zhang Tian-liang, Wang Bin, Li Xian-wei. An efficacy analysis of bupropion for smoking cessation in schizophrenia. Zhongguo Xinyao yu Linchuang Zazhi 2009;28(3):231-4.
*Weiner 2011 {published data only}
  • Weiner E. Comparison of Varenicline and Placebo for Smoking Cessation in Schizophrenia. www.clinicaltrials.gov/ct2/show/NCT00554840 (accessed on 31/03/2010).
  • Weiner E, Buchholz A, Coffay A, Liu F, McMahon RP, Buchanan RW, et al. Varenicline for smoking cessation in people with schizophrenia: a double blind randomized pilot study. Schizophrenia Research 2011;129(1):94-5. [CRS-ID: 9400123000011383; : 6459]
*Weiner 2012 {published data only}
  • Weiner E, Ball MP, Buchanan R, Gold JM. A comparison of Bupropion SR and Placebo for Smoking Cessation. Conference abstract of the International Congress on Schizophrenia Research: Colorado Springs, Colorado, USA. 2007.
  • Weiner E, Ball MP, Buchholz AS, Gold JM, Evins AE, McMahon RP, et al. Bupropion sustained release added to group support for smoking cessation in schizophrenia: a new randomized trial and a meta-analysis. Journal of Clinical Psychiatry. United States, 2012; Vol. 73, issue 1:95-102. [CRS-ID: 9400123000011967]
  • Weiner E, Buchanan R, Gold J, Ball P, Bennett M. A comparison of bupropion SR and placebo for smoking cessation in schizophrenia. Schizophrenia Research 2003;60:305-6.
*Williams 2007 {published data only}
  • Williams JM, Gandhi KK, Foulds J, Steinberg M, Lou S, Masumova F, et al. No advantage for high dose compared to regular dose nicotine patch on short-term abstinence rates in schizophrenia (PA2-3). Conference abstract of the Society for Research on Nicotine and Tobacco 13th Annual Meeting: Austin, Texas, USA. 2007.
*Williams 2010 {published data only}
  • Steinberg ML, Williams J. Psychosocial Treatments for Individuals with Schizophrenia and Tobacco Dependence. Journal of Dual Diagnosis 2007;3(3/4):99-112.
  • Williams JM, Steinberg ML, Zimmermann MH, Gandhi KK, Stipelman B, Budsock PD, et al. Comparison of two intensities of tobacco dependence counselling in schizophrenia and schizoaffective disorder. Journal of Substance Abuse Treatment 2010; Vol. 38, issue 4:384-93. [CRS-ID: 9400123000005641]
  • Ziedonis D, Williams J, Zimmermann M, Krejci J, Steinbery M, Foulds J, Violette N, Agatep B, Sawh L, Gaffney J. Behavioral Therapy Development for Smokers with Schizophrenia. Conference abstract of the 13th World Conference on Tobacco OR Health: Washington DC, USA. 2006.
*Williams 2012 {published data only}
  • Pfizer. Smoking Cessation Study for Patients With Schizophrenia or Schizoaffective Disorder. www.clinicaltrials.gov/ct2/show/NCT00644969 (accessed on 31/03/2010).
  • Williams JM, Anthenelli RM, Morris CD, Treadow J, Thompson JR, Yunis C, et al. A randomized, double-blind, placebo-controlled study evaluating the safety and efficacy of varenicline for smoking cessation in patients with schizophrenia or schizoaffective disorder. Journal of Clinical Psychiatry. United States, 2012; Vol. 73, issue 5:654-60. [CRS-ID: 9400123000013848]
*Wing 2012 {published data only}
  • George T. rTMS Effects on Smoking Cessation and Cognition in Schizophrenia. www.clinicaltrials.gov/ct2/show/NCT00736710 (accessed on 31/03/2010).
  • Wing V C, Bacher I, Daskalakis Z J, George T. A preliminary study of repetitive transcranial magnetic stimulation for smoking cessation in schizophrenia. Neuropsychopharmacology (Conference Proceedings of 49th Annual Conference of the American College of Neuropsychopharmacology, ACNP, 5/12/2010-9/12/2010 Miami Beach, FL United States). 2010; Vol. 35:S163.
  • Wing Victoria C, Bacher Ingrid, Wu Becky S, Daskalakis Zafiris J, George Tony P. High frequency repetitive transcranial magnetic stimulation reduces tobacco craving in schizophrenia. Schizophrenia Research 2012;139(1-3):264-6.
+Akbarpour 2010 {published data only}
  • Akbarpour F, Rezaei O, Khodaie-Ardakani MR, Sheikhvatan M, Goodarzi H, Dolatshahi B. A double-blind placebo-controlled trial of bupropion for smoking abstinence and cognition improvement in schizophrenia. Minerva Psichiatrica 2010; Vol. 51, issue 4:263-9. [CRS-ID: 9400123000006034]
+Bloch 2010 {published data only}
  • Bloch B, Reshef A, Cohen T, Tafla A, Gathas S, Israel S, et al. Preliminary effects of bupropion and the promoter region (HTTLPR) serotonin transporter (SLC6A4) polymorphism on smoking behavior in schizophrenia. Psychiatry Research 2010; Vol. 175, issue 1-2:38-42.
+Dalack 1999 {published and unpublished data}
  • Dalack GW, Becks L, Hill E, Pomerleau O, Meador-Woodruff JH. Nicotine Withdrawal and Replacement in Schizophrenia. Conference abstract from the 150th Annual Meeting of the American Psychiatric Association: San Diego, California, USA. 1997.
  • Dalack GW, Becks L, Hill E, Pomerleau O, Meador-Woodruff JH. The effects of treated and untreated nicotine withdrawal on smokers with schizophrenia. Schizophrenia Research (conference abstract from the 6th International Congress on Schizophrenia Research, Colorado Springs, Colorado, USA). 1997; Vol. 24:63.
  • Dalack GW, Becks L, Hill E, Pomerleau OF, Meador-Woodruff JH. Nicotine withdrawal and psychiatric symptoms in cigarette smokers with schizophrenia. Neuropsychopharmacology 1999;21:195-202.
  • Dalack GW, Meador-Woodruff JH. Acute feasibility and safety of a smoking reduction strategy for smokers with schizophrenia. Nicotine & Tobacco Research 1999;1(1):53-7.
  • Dalack GW, Meador-Woodruff JH. The Nicotine Patch, Smoking and Schizophrenia. Conference abstract from the 150th Annual Meeting of the American Psychiatric Association: San Diego, California, USA. 1997.
+Fatemi 2005 {published data only}
  • Fatemi S, Stary J, Hatsukami D, Murphy S. A double-blind placebo-controlled cross over trial of bupropion in smoking reduction in schizophrenia [Letter to the Editor]. Schizophrenia Research 2005;76(2-3):353-6.
+Gelkopf 2012 {published and unpublished data}
  • Gelkopf M, Noam S, Rudinski D, Lerner A, Behrbalk P, Bleich A, et al. Nonmedication smoking reduction program for inpatients with chronic schizophrenia: a randomized control design study. Journal of Nervous and Mental Disease. United States: Lippincott Williams and Wilkins (351 West Camden Street, Baltimore MD 21201-2436, United States), 2012; Vol. 200, issue 2:142-6. [CRS-ID: 9400123000011977]
+Hartman 1991 {published data only}
  • Hartman N, Leong GB, Glynn SM, Wilkins JN, Jarvik ME. Transdermal nicotine and smoking behavior in psychiatric patients. American Journal of Psychiatry 1991;148(3):374-5.
+Steinberg 2003 {published and unpublished data}
  • Steinberg ML. Engaging smokers with schizophrenia in treatment for tobacco dependence: A brief motivational interviewing intervention. Dissertation Abstracts International: Section B: The Sciences and Engineering 2003; Vol. 64, issue 3-B:1508.
  • Steinberg ML, Ziedonis DM, Krejci JA, Brandon TH. Motivational interviewing with personalized feedback: a brief intervention for motivating smokers with schizophrenia to seek treatment for tobacco dependence. Journal of Consulting & Clinical Psychology 2004;72(4):723-8.
+Szombathyne 2010 {published data only}
  • Szombathyne-Meszaros Z, Dimmock J A, Ploutz-Snyder R, Batki S L. Oral naltrexone treatment for alcohol dependence in schizophrenia is not effective for smoking cessation. Alcoholism: Clinical and Experimental Research 2010;34(6):176A.
+Tidey 2011 {published and unpublished data}
  • Tidey JW. Contingent Incentives Plus Bupropion for Smoking in People With Schizophrenia. www.clinicaltrials.gov/ct2/show/NCT00136760 (accessed on 31/03/2010).
  • Tidey JW, Rohsenow DJ, Kaplan GB, Swift RM, Reid N. Effects of contingency management and bupropion on cigarette smoking in smokers with schizophrenia. Psychopharmacology 2011; Vol. 217, issue 2:279-87. [CRS-ID: 9400123000011584]
de Leon 2005b {published and unpublished data}
  • de Leon J, Diaz FJ, Josiassen RC, Cooper TB, Simpson GM. Does clozapine decrease smoking?. Progress in Neuro-Psychopharmacology & Biological Psychiatry 2005;29(5):757-62.
  • Simpson GM, Josiassen RC, Stanilla JK, de Leon J, Nair C, Abraham G, et al. Double-blind study of clozapine dose response in chronic schizophrenia. American Journal of Psychiatry 1999;156:1744-50.
Hong 2011 {published data only}
  • Hong E. Moderate Dose Varenicline Treatment on Neurobiological and Cognitive Biomarkers in Schizophrenia Smokers and Non-smokers. Neuropsychopharmacology (Conference proceedings of the 50th Annual Meeting of the American College of Neuropsychopharmacology 4/12/11 to 8/12/11, ACNP Waikoloa, HI United States). 2011; Vol. 36:S97-S98.
  • Hong LE, Thaker GK, McMahon RP, Summerfelt A, RachBeisel J, Fuller RL, Wonodi I, Buchanan RW, Myers C, Heishman SJ, Yang J, Nye Adrienne. Effects of moderate-dose treatment with varenicline on neurobiological and cognitive biomarkers in smokers and nonsmokers with schizophrenia or schizoaffective disorder. Archives of General Psychiatry 2011;68(12):1195-1206.
Kelly 2008 {published and unpublished data}
  • Buchanan RW, Conley RR, Dickinson D, Ball MP, Feldman S, Gold J, et al. Galantamine for the treatment of cognitive impairments in people with schizophrenia. American Journal of Psychiatry 2008;165:82-9.
  • Kelly DL, McMahon RP, Weiner E, Boggs DL, Dickinson D, Conley RR, et al. Lack of beneficial galantamine effect for smoking behavior: a double-blind randomized trial in people with schizophrenia. Schizophrenia Research 2008;103(1-3):161-8.
McEvoy 1995 {published data only}
Meszaros 2012 {published and unpublished data}
  • Meszaros ZS. Varenicline Treatment in Alcohol and Nicotine Dependent Patients With Schizophrenia. www.clinicaltrials.gov/ct2/show/NCT00727103 (accessed on 31/03/2010).
  • Meszaros ZS, Abdul-Malak Y, Dimmock J A, Wang D, Batki S L. Varenicline treatment of alcohol and nicotine dependence in schizophrenia: Problems encountered in a pilot trial. American Journal on Addictions (Conference Proceedings of 22nd Annual Meeting and Symposium of the American Academy of Addiction Psychiatry, AAAP 8/12/2011-11/12/2011, Scottsdale, AZ United States). 2012; Vol. 21, issue 4:393-4.
Sacco 2009 {published data only}
  • Sacco K A, Creeden C, Reutenauer E L, Vessicchio J C, Weinberger A H, George T P, et al. Effects of atomoxetine on cognitive function and cigarette smoking in schizophrenia. Schizophrenia Research 2009; Vol. 107, issue 2-3:332-3.
Shim 2012 {published data only}
  • Shim JC, Jung D, Oh M, Kong B, Ha T, Cho D, et al. Varenicline treatment for smoking cessation in people with schizophrenia: A randomized double-blind placebo-controlled trial. Schizophrenia Bulletin. 2011; Vol. 37:320-1. [CRS-ID: 9400123000006139]
  • Shim J C, Jung D U, Jung S S, Seo Y S, Cho D M, Lee J H, et al. Adjunctive Varenicline Treatment with Antipsychotic Medications for Cognitive Impairments in People with Schizophrenia: A Randomized Double-Blind Placebo-Controlled Trial. Neuropsychopharmacology 2012;37(3):660-8.
Weinberger 2008 {published and unpublished data}
  • Chengappa KNR, Kupfer DJ, Parepally H, John V, Basu R, Buttenfield J, et al. A placebo-controlled, random-assignment, parallel-group pilot study of adjunctive topiramate for patients with schizoaffective disorder, bipolar type. Bipolar Disorder 2007;9(6):609-17.
  • Weinberger AH, George TP, Perkins KA, Chengappa KNR. Effects of topiramate on smoking in patients with schizoaffective disorder, bipolar type. Journal of Clinical Psychopharmacology 2008;28(2):247-8.
  • Weinberger AH, George TP, Perkins KA, Chengappa KNR. Effects of topiramate on smoking patients with schizoaffective disorder, bipolar type: Response to Khazaal and Zullino. Journal of Clinical Psychopharmacology 2009;29:193-194.

References to studies excluded from this review

  1. References to studies included in this review
  2. References to studies excluded from this review
  3. References to studies awaiting assessment
  4. References to ongoing studies
  5. Additional references
  6. References to other published versions of this review
Allen 2011 {published data only}
  • Allen MH, Debanné M, Lazignac C, Adam E, Dickinson LM, Damsa C. Effect of nicotine replacement therapy on agitation in smokers with schizophrenia: a double-blind, randomized, placebo-controlled study. American Journal of Psychiatry 2011;168(4):395-9.
  • Damsa C, Lazignac C, Adam E, Virgillito S, Allen MH. Effect of nicotine replacement on agitation and aggression in smokers with schizophrenia: a double blind, randomized placebo controlled pilot study. Proceedings of the 162nd Annual Meeting of the American Psychiatric Association; 2009 May 16 21; San Francisco , CA. 2009. [CRS-ID: 9400123000013817; : 30292]
Arbour-Nicitopoulos 2011a {published data only}
  • Arbour-Nicitopoulos K P, Faulkner G E, Cohn T A, Selby P. Smoking Cessation in Women With Severe Mental Illness: Exploring the Role of Exercise as an Adjunct Treatment. Archives of Psychiatric Nursing 2011;25(1):43-52.
Arbour-Nicitopoulos 2011b {published data only}
  • Arbour-Nicitopoulos K P, Faulkner G E, Hsin A, Selby P. A pilot study examining the acute effects of exercise on cigarette cravings and affect among individuals with serious mental illness. Mental Health and Physical Activity 2011;4(2):89-94.
Aubin 2012 {published data only}
  • Aubin HJ, Rollema H, Svensson TH, Winterer G. Smoking, quitting, and psychiatric disease: a review. Neuroscience and Biobehavioral Reviews. United States, 2012; Vol. 36, issue 1:271 // 284. [CRS-ID: 9400123000013853]
Baker 2010 {published data only}
  • Baker Amanda L, Lubman Dan I, Hides Leanne. Smoking and schizophrenia: Treatment approaches within primary care. Primary Psychiatry 2010;17(1):49-54.
Banham 2010 {published data only}
Brown 2003 {published data only}
  • Brown RA, Ramsey SE, Strong DR, Myers MG, Kahler CW, Lejuez CW, et al. Effects of motivational interviewing on smoking cessation in adolescents with psychiatric disorders. Tobacco Control 2003;12 Suppl 4:iv3-iv10.
Brunette 2011 {published data only}
  • Brunette M F, Ferron J C, McHugo G J, Davis K E, Devitt T S, Wilkness S M, et al. An Electronic Decision Support System to Motivate People With Severe Mental Illnesses to Quit Smoking. Psychiatric Services 2011;62(4):360-6.
Bryant 2011 {published data only}
Dutra 2012 {published data only}
  • Dutra SJ, Stoeckel LE, Carlini SV, Pizzagalli DA, Evins AE. Varenicline as a smoking cessation aid in schizophrenia patients: Effects on smoking behavior and reward sensitivity. Biological Psychiatry 2011; Vol. 69, issue 9 SUPPL. 1:280S. [CRS-ID: 9400123000006137]
  • Dutra Sunny J, Stoeckel Luke E, Carlini Sara V, Pizzagalli Diego A, Evins AE, Dutra SJ, et al. Varenicline as a smoking cessation aid in schizophrenia: Effects on smoking behavior and reward sensitivity. Psychopharmacology 2012; Vol. 219, issue 1:25-34. [CRS-ID: 9400123000013181]
Kisely 2006 {published data only}
  • Kisely SR, Preston NJ. A Group Intervention which assists patients with dual diagnosis reduce their tobacco use. In: Abelian ME editor(s). Trends in psychotherapy research. Hauppauge, NY: Nova Science Publishers, 2006:141-59.
McClure 2010 {published data only}
  • McClure J B, Swan G E, Catz S L, Jack L, Javitz H, McAfee T, et al. Smoking outcome by psychiatric history after behavioral and varenicline treatment. Journal of Substance Abuse Treatment 2010;38(4):394-402.
McEvoy 1999 {published data only}
McKee 2009 {published data only}
  • McKee SA, Weinberger AH, Harrison ELR, Coppola S, George TP. Effects of the nicotinic receptor antagonist mecamylamine on ad-lib smoking behaviour, topography, and nicotine levels in smokers with and without schizophrenia: a preliminary study. Schizophrenia Research 2009;115:317-24.
Morris 2011 {published data only}
  • Morris C D, Waxmonsky J A, May M G, Tinkelman D G, Dickinson M, Giese A A, et al. Smoking reduction for persons with mental illnesses: 6-month results from community-based interventions. Community Mental Health Journal 2011;47(6):694-702.
Pachas 2012 {published data only}
  • Pachas G N, Cather C, Pratt S I, Hoeppner B, Nino J, Carlini S V, et al. Varenicline for Smoking Cessation in Schizophrenia: Safety and Effectiveness in a 12-Week Open-Label Trial. Journal of Dual Diagnosis 2012;8(2):117-25.
Roll 1998 {published data only}
  • Roll JM, Higgins ST, Steingard S, McGinley M. Use of monetary reinforcement to reduce the cigarette smoking of persons with schizophrenia: a feasibility study. Experimental & Clinical Psychopharmacology 1998;6(2):157-61.
Shiina 2010 {published data only}
  • Shiina A, Shirayama Y, Niitsu T, Hashimoto T, Yoshida T, Hasegawa T, et al. A randomised, double-blind, placebo-controlled trial of tropisetron in patients with schizophrenia. Annals of General Psychiatry 2010;9:27.
Tidey 2002 {published data only}
  • Tidey JW, O'Neill SC, Higgins ST. Contingent monetary reinforcement of smoking reductions, with and without transdermal nicotine, in outpatients with schizophrenia. Experimental & Clinical Psychopharmacology 2002;10(3):241-7.
Tidey 2012 {published data only}
  • Tidey JW, Rohsenow DJ, Kaplan GB, Swift RM, Ahnallen CG. Separate and Combined Effects of Very Low Nicotine Cigarettes and Nicotine. Nicotine & Tobacco Research 2012; Vol. epub. [CRS-ID: 9400123000013849]
Weiner 2001 {published data only}
  • Weiner E, Ball MP, Summerfelt A, Gold J, Buchanan RW. Effects of sustained-release bupropion and supportive group therapy on cigarette consumption in patients with schizophrenia. American Journal of Psychiatry 2001;158(4):635-7.
Wells 2003 {published data only}
  • Wells ME. Increasing motivation to stop smoking among persons with schizophrenia and other chronic mental illnesses. Dissertation Abstracts International: Section B: The Sciences and Engineering 2003; Vol. 63, issue 8-B.

References to studies awaiting assessment

  1. References to studies included in this review
  2. References to studies excluded from this review
  3. References to studies awaiting assessment
  4. References to ongoing studies
  5. Additional references
  6. References to other published versions of this review
Chen 2002 {published data only}
  • Chen R, Ku C, Chou K, Shen C. The impact of smoking cessation programs on schizophrenic patients' smoking behaviors [abstract]. American Journal of Respiratory and Critical Care Medicine 2002;165(8 Suppl):A309.
  • Chen R, Ku C-H, Lu R-B, Chou K-R. The impact of smoking cessation programs on smoking-related health belief and rate of quit-smoking among schizophrenic patients. Journal of Medical Sciences 2002;22(5):215-20.
Chou 2004 {published data only}
  • Chou KR, Chen R, Lee JF, Ku CH, Lu RB. The effectiveness of nicotine-patch therapy for smoking cessation in patients with schizophrenia. International Journal of Nursing Studies 2004;41(3):321-30.

References to ongoing studies

  1. References to studies included in this review
  2. References to studies excluded from this review
  3. References to studies awaiting assessment
  4. References to ongoing studies
  5. Additional references
  6. References to other published versions of this review
Baker(ACTRN1260900103927) {published data only}
  • Baker A. Healthy lifestyle intervention for cardiovascular disease risk reduction among smokers with psychotic disorders. www.anzctr.org.au/trial_view.aspx?ID=308232 (accessed on 11/4/2010).
  • Baker A, Kay-Lambkin FJ, Richmond R, Filia S, Castle D, Williams J, et al. Study protocol: a randomised controlled trial investigating the effect of a healthy lifestyle intervention for people with severe mental disorders. BMC Public Health 2011; Vol. 11, issue 1:10.
  • Baker A L, Kay-Lambkin F J, Richmond R, Filia S, Castle D, Williams J, et al. Healthy lifestyle intervention for people with severe mental disorders. Mental Health and Substance Use: Dual Diagnosis 2010;4 (2):144-57.
  • Filia S, Baker A, Richmond R, Kay-Lambkin F, Castle D, Williams J, et al. Randomised controlled trial of a healthy lifestyles intervention to reduce cardiovascular disease (CVD) risk among smokers with psychosis: Interim results. Australian and New Zealand Journal of Psychiatry 2010;44:A31-A32. [CRS-ID: 9400123000006114]
Dixon (NCT00960375) {published data only}
  • Dixon L B, Potts W. Smoking cessation for veterans with severe and persistent mental illness. www.clinicaltrials.gov/ct2/show/NCT00960375 (accessed on 20/7/12).
Evins (NCT00621777) {published data only}
  • Evins AE. A study of Varenicline for Prevention of Relapse to Smoking in Patients with Schizophrenia or Bipolar Disorder (SCRP). www.clinicaltrials.gov/ct2/show/NCT00621777 (accessed on 12/11/2012).
Fatemi (NCT01111149) {published data only}
  • Fatemi SH. Varenicline and smoking cessation in schizophrenia (VSCS). http://www.clinicaltrials.gov/ct2/show/NCT01111149 (accessed on 20/7/12).
Josiassen (NCT00231101) {published data only}
  • Josiassen RJ. Quetiapine Decreases Smoking in Patients With Chronic Schizophrenia. www.clinicaltrials.gov/ct2/show/NCT00231101 (accessed on 31/03/2010).
Saxon (NCT00508560) {published data only}
  • Saxon AJ. Contingency Management for Smoking Cessation Among Veterans With Psychotic Disorders. www.clinicaltrials.gov/ct2/show/NCT00508560 (accessed on 12/11/2012).
Smith (NCT00802919) {published data only}
  • Smith RC. Varenicline for Cognitive Deficits and Cigarette Smoking in Schizophrenia - Efficacy and Predictors. www.clinicaltrials.gov/ct2/show/NCT00802919 (accessed on 12/11/2012).
Stockings 2011 {published data only}
  • The effect of an integrated smoking care program on the reduction and abstinence of smoking in mental health inpatients following discharge from hospital. http://www.anzctr.org.au/trial_view.aspx?ID=83938 (accessed on 16/11/2012).
  • Stockings EA, Bowman JA, Wiggers J, Baker AL, Terry M, Clancy R, et al. A randomised controlled trial linking mental health inpatients to community smoking cessation supports: a study protocol. BMC Public Health 2011;11:570.
Williams (NCT01010477) {published data only}
  • Trial of Nicotine Nasal Spray as an Aid for Smoking Cessation in Schizophrenia. http://www.clinicaltrials.gov/ct2/show/NCT01010477 (accessed on 12/11/2012).

Additional references

  1. References to studies included in this review
  2. References to studies excluded from this review
  3. References to studies awaiting assessment
  4. References to ongoing studies
  5. Additional references
  6. References to other published versions of this review
Adler 1998
  • Adler LE, Olincy A, Waldo M, Harris JG, Griffith J, Stevens K, et al. Schizophrenia, sensory gating, and nicotinic receptors. Schizophrenia Bulletin 1998;24(2):189-202.
American Psychiatric Association 1994
  • American Psychiatric Association. Diagnostic and Statistical Manual of Mental Disorder. 4th Edition. Washington, DC: American Psychiatric Association, 1994.
Amiaz 2009
Brown 2000
Buchanan 2009
  • Buchanan RW, Kreyenbuhl J, Kelly DL, Noel JM, Boggs DL, Fischer BA, et al. The 2009 Schizophrenia PORT Psychopharmacological Treatment Recommendations and Summary Statements. Schizophrenia Bulletin 2010;36(1):71-93.
Cahill 2011
  • Cahill K, Perera R. Competitions and incentives for smoking cessation. Cochrane Database of Systematic Reviews 2011, Issue 4. [DOI: 10.1002/14651858.CD004307.pub4]
Cahill 2012
Cerimele 2012
  • Cerimele JM, Durango A. Does Varenicline Worsen Psychiatric Symptoms in Patients With Schizophrenia or Schizoaffective Disorder? A Review of Published Studies. Journal of Clinical Psychiatry 2012;73(8):e1039-1047.
Cuervo 2003
Culhane 2008
  • Culhane MA, Schoenfeld DA, Barr RS, Cather C, Deckersbach T, Freudenreich O, et al. Predictors of early abstinence in smokers with schizophrenia. Journal of Clinical Psychiatry 2008;69(11):1743-50.
de Leon 2005a
Desai 2001
Dixon 1999
Dixon 2009
  • Dixon L, Perkins D, Calmes C. Guideline Watch (September 2009): Practice Guideline for the Treatment of Patients with Schizophrenia. American Psychiatric Publishing, 2009.
Eichhammer 2003
  • Eichhammer P, Johann M, Kharraz A, Binder H, Pittrow D, Wodarz N, Hajak G. High-frequency repetitive transcranial magnetic stimulation decreases cigarette smoking. Journal of Clinical Psychiatry 2003;64(8):951-953.
Ereshefsky 1985
FDA 2008
  • US Food, Drug Administration. Public Health Advisory: Important Information on Chantix (varenicline). http://www.fda.gov/Drugs/DrugSafety/PostmarketDrugSafetyInformationforPatientsandProviders/DrugSafetyInformationforHeathcareProfessionals/PublicHealthAdvisories/ucm051136.htm (accessed on 30/11/12).
FDA 2011
  • US Food, Drug Administration. [FDA drug safety communication: safety review update of Chantix (varenicline) and risk of neuropsychiatric adverse events.]. http://www.fda.gov/Drugs/DrugSafety/ucm276737.htm (accessed 30/11/2012) October 2011.
Fiore 2008
  • Fiore M, Jaén C, Baker T, Bailey W, Benowitz NL, Curry S, et al. Treating tobacco use and dependence: 2008 Update - Clinical Practice Guideline. United States Department of Health and Human Services, 2008.
Freedman 2007
GlaxoSmithKline 2008
  • Prescribing Information (Wellbutrin XL - bupropion hydrochloride extended-release tablets). http://us.gsk.com/products/assets/us_wellbutrinXL.pdf 2008.
Goff 1992
  • Goff DC, Henderson DC, Amico E. Cigarette smoking in schizophrenia: Relaitonship to psychopathology and medication side effects. American Journal of Psychiatry 1992;149(9):1189-94.
Gunnell 2009
  • Gunnell D, Irvine D, Wise L, Davies C, Martin RM. Varenicline and suicidal behaviour: a cohort study based on data from the General Practice Research Database. British Medical Journal 2009;339:b3805.
Gustafson 1992
  • Gustafson R. Operant conditioning of activities of daily living on a psychogeriatric ward: A simple method. Psychological Reports 1992;70:603-7.
Harrison-Woolrych 2011
  • Harrison-Woolrych M, Ashton J. Psychiatric adverse events associated with varenicline: an intensive postmarketing prospective cohort study in New Zealand. Drug Safety 2011;34(9):763-772.
Higgins 2003
Higgins 2011
  • Higgins JPT, Green S [eds]. Cochrane Handbook for Systematic Reviews of Interventions,5.1.0 [updated March 2011]. The Cochrane Collaboration, 2011.
Hughes 2005
Hughes 2006
Hughes 2007
Johnson 2005
  • Johnson BA. Recent advances in the development of treatments for alcohol and cocaine dependence: focus on topiramate and other modulators of GABA or glutamate function. CNS Drugs 2005;19:873-896.
Kasliwal 2009
  • Kasliwal R, Wilton LV, Shakir SA. Safety and drug utilization profile of varenicline as used in general practice in England: interim results from a prescription-event monitoring study. Drug Safety 2009;32(6):499-507.
Kelly 1999
  • Kelly C, McCreadie RG. Smoking habits, current symptoms, and premorbid characteristics of schizophrenic patients in Nithsdale, Scotland. American Journal of Psychiatry 1999;156(11):1751-7.
Kelly 2011
Kelly 2012
  • Kelly DL, Raley HG, Lo S, Wright K, Liu F, McMahon RP, Moolchan ET, Feldman S, Richardson CM, Wehring HJ, Heishman SJ. Perception of Smoking Risks and Motivatin to Quit Among Nontreatment-Seeking Smokers With and Without Schizophrenia. Schizophrenia Bulletin 2012;38(3):543-551. [DOI: 10.1093/schbul/sbq124]
Kreyenbuhl 2009
  • Kreyenbuhl J, Buchanan RW, Dickerson FB, Dixon LB. The Schizophrenia Patient Outcomes Research Team (PORT): Updated Treatment Recommendations 2009. Schizophrenia Bulletin 2010;36(1):94-103.
Kumari 2002
  • Kumari V, Sharma T. Effects of typical and atypical antipsychotics on prepulse inhibition in schizophrenia: A critical evaluation of current evidence and directions for future research. Psychopharmacology 2002;162(2):97-101.
Lai 2010
Lancaster 2005a
Lancaster 2005b
  • Lancaster T, Stead LF. Self-help interventions for smoking cessation. Cochrane Database of Systematic Reviews 2005, Issue 3. [DOI: 10.1002/14651858.CD001118.pub2]
Lawn 2005
Lichtermann 2001
Liu 2009
  • Liu ME, Tsai SJ, Yang ST. Varenicline-induced mixed mood and psychotic episode in a patient with Schizoaffective Disorder. CNS Spectrum 2009;14:346.
McEvoy 1995a
Moore 2011
Moss 2009
  • Moss TG, Sacco KA, Allen TM, Weinberger AH, Vessicchio JC, George TP. Prefrontal cognitive dysfunction is associated with tobacco dependence treatment failure in smokers with schizophrenia. Drug and Alcohol Dependence 2009;104(1-2):94-9.
Olincy 1997
Sacco 2004
Shadel 2000
  • Shadel WG, Shiffman S, Niaura R, Nichter M, Abrams DB. Current models of nicotine dependence: What is known and what is needed to advance understanding of tobacco etiology among youth. Drug and Alcohol Dependence 2000;59 Suppl 1:S9-22.
Shmueli 2008
  • Shmueli D, Fletcher L, Hall SE, Hall SM, Prochaska JJ. Changes in psychiatric patients' thoughts about quitting smoking during a smoke-free hospitalization. Nicotine & Tobacco Research 2008;10(5):875-81.
Stead 2005
Stead 2006
  • Stead LF, Perera R, Lancaster T. Telephone counselling for smoking cessation. Cochrane Database of Systematic Reviews 2006, Issue 3. [DOI: 10.1002/14651858.CD002850.pub2]
Stead 2008
Stead 2012
  • Stead LF, Lancaster T. Combined pharmacotherapy and behavioural interventions for smoking cessation. Cochrane Database of Systematic Reviews 2012, Issue 10. [DOI: 10.1002/14651858.CD008286.pub2]
Stead 2012b
  • Stead LF, Perera R, Bullen C, Mant D, Hartmann-Boyce J, Cahill K, Lancaster T. Nicotine replacement therapy for smoking cessation. Cochrane Database of Systematic Reviews 2012, Issue 11. [DOI: 10.1002/14651858.CD000146.pub4]
Steinberg 2004
Strasser 2001
  • Strasser K. Smoking Reduction and Cessation for People with Schizophrenia: Guidelines for General Practitioners. Smoking Reduction and Cessation for People with Schizophrenia:Guidelines for General Practitioners. SANE Australia & Department of Psychiatry, University of Melbourne, 2001.
Tunis 2003
  • Tunis SR, Stryer DB, Clancy CM. Practical clinical trials: increasing the value of clinical research for decision making in clinical and health policy. Journal of American Medical Association 2003;290(12):1624-32.
US Department of Health and Human Services 2000
  • US Department of Health and Human Services. Reducing Tobacco Use. A Report of the US Surgeon General. Atlanta, GA: Office of Smoking and Health, 2000.
West 2005
Williams 2005
  • Williams JM, Ziedonis DM, Abanyie F, Steinberg ML, Foulds J, Benowitz NL. Increased nicotine and cotinine levels in smokers with schizophrenia and schizoaffective disorder is not a metabolic effect. Schizophrenia Research 2005;79(2-3):323-35.
Williams 2006
  • Williams JM, Ziedonis DM. Snuffing out tobacco dependence. Ten reasons behavioral health providers need to be involved. Behavioral Healthcare 2006;26(5):27-31.
Workgroup on Substance Use Disorders 2006
  • Workgroup on Substance Use Disorders, American Psychiatric Association Steering Committee on Practice Guidelines. Practice Guideline for the Treatment of Patients With Substance Use Disorders. 2nd Edition. American Psychiatric Association, 2006.
World Health Organization 2003
  • World Health Organization. International Classification of Diseases. 10th Edition. WHO, 2003.
Wye 2009
  • Wye PM, Bowman JA, Wiggers JH, Baker A, Knight J, Carr VJ, et al. Smoking restrictions and treatment for smoking: policies and procedures in psychiatric inpatient units in Australia. Psychiatric Service 2009;60(1):100-7.
Ziedonis 1994
  • Ziedonis D, Kosten TR, Glazer WM, Frances RJ. Nicotine dependence and schizophrenia. Hospital and Community Psychiatry 1994;45(3):204-6.
Ziedonis 2007
  • Ziedonis D, Parks J, Zimmermann MH, McCabe P. Program and System Level Interventions to Address Tobacco Amongst Individuals with Schizophrenia. Journal of Dual Diagnosis 2007;3(3/4):151-175.
Zwar 2007
  • Zwar N, Richmond R, Borland R, Peters M, Stilman S, Litt J, et al. Smoking cessation pharmacotherapy: an update for health professionals. Royal Australian College of General Practitioners, 2007.

References to other published versions of this review

  1. References to studies included in this review
  2. References to studies excluded from this review
  3. References to studies awaiting assessment
  4. References to ongoing studies
  5. Additional references
  6. References to other published versions of this review
Tsoi 2010
  • Tsoi DT, Porwal M, Webster AC. Efficacy and safety of bupropion for smoking cessation and reduction in schizophrenia: systematic review and meta-analysis. British Journal of Psychiatry 2010;196:346-353.