Anaesthetic interventions for prevention of awareness during surgery

  • Protocol
  • Intervention



This is the protocol for a review and there is no abstract. The objectives are as follows:

The objective of this review is to evaluate the efficacy of two types of anaesthetic interventions on reducing clinically significant awareness:

  1. anaesthetic drug regimens; and

  2. intraoperative anaesthetic depth monitors (ADM).

Categories of anaesthetic drug regimens include: (1) intravenous (IV); (2) pure inhalational, including the following subgroups: (2a) inhalation used for induction and maintenance, (2b) IV induction and inhalational maintenance, where the IV induction or inhalational agent for maintenance are varied; (3) inhalational with narcotics as compared to a 'pure' inhalational technique; (4) all of the above regimens with and without muscle relaxants (MRs); (5) any of these previous techniques with regional anaesthesia.

ADMs include: Bispectral index (BIS) monitor, Narcotrend monitor, cerebral function monitor, cerebral state monitor, patient state index, and lower oesophageal contractility monitor.