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Vitamin D supplementation for cystic fibrosis

  1. Janet H Ferguson1,*,
  2. Anne B Chang2

Editorial Group: Cochrane Cystic Fibrosis and Genetic Disorders Group

Published Online: 14 MAY 2014

Assessed as up-to-date: 7 MAY 2014

DOI: 10.1002/14651858.CD007298.pub4


How to Cite

Ferguson JH, Chang AB. Vitamin D supplementation for cystic fibrosis. Cochrane Database of Systematic Reviews 2014, Issue 5. Art. No.: CD007298. DOI: 10.1002/14651858.CD007298.pub4.

Author Information

  1. 1

    Canterbury District Health Board, Christchurch Hospital, Christchurch, New Zealand

  2. 2

    Menzies School of Health Research, Charles Darwin University, Child Health Division, Darwin, Northern Territories, Australia

*Janet H Ferguson, Christchurch Hospital, Canterbury District Health Board, Private Bag 4710, Christchurch, 8140, New Zealand. janet.ferguson@actrix.co.nz. janet.ferguson@cdhb.health.nz.

Publication History

  1. Publication Status: New search for studies and content updated (no change to conclusions)
  2. Published Online: 14 MAY 2014

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[Figure 1]
Figure 1. Risk of bias summary: review authors' judgements about each risk of bias item for each included study.
[Figure 2]
Figure 2. Forest plot of comparison: 1 Vitamin D versus placebo, outcome: 1.2 Serum calcium (absolute final) [mmol/L].
[Figure 3]
Figure 3. Forest plot of comparison: 1 Vitamin D versus placebo, outcome: 1.3 25(OH)D [ng/ml].
[Figure 4]
Figure 4. Forest plot of comparison: 1 Vitamin D versus placebo, outcome: 1.5 PTH levels (absolute final) [pmol/L].
[Analysis 1.1]
Analysis 1.1. Comparison 1 Vitamin D versus placebo, Outcome 1 Serum calcium change (mmol/L).
[Analysis 1.2]
Analysis 1.2. Comparison 1 Vitamin D versus placebo, Outcome 2 Serum calcium (absolute final).
[Analysis 1.3]
Analysis 1.3. Comparison 1 Vitamin D versus placebo, Outcome 3 25(OH)D.
[Analysis 1.4]
Analysis 1.4. Comparison 1 Vitamin D versus placebo, Outcome 4 1,25(OH)2D (absolute final).
[Analysis 1.5]
Analysis 1.5. Comparison 1 Vitamin D versus placebo, Outcome 5 PTH levels (absolute final).
[Analysis 1.6]
Analysis 1.6. Comparison 1 Vitamin D versus placebo, Outcome 6 PTH levels (change from baseline).
[Analysis 2.1]
Analysis 2.1. Comparison 2 Post-hoc analysis: Vitamin D versus placebo, Outcome 1 Whole body bone mineral content change (g).
[Analysis 2.2]
Analysis 2.2. Comparison 2 Post-hoc analysis: Vitamin D versus placebo, Outcome 2 Lumbar spine z score.
[Analysis 2.3]
Analysis 2.3. Comparison 2 Post-hoc analysis: Vitamin D versus placebo, Outcome 3 Lumbar spine bone mineral density (% change).
[Analysis 2.4]
Analysis 2.4. Comparison 2 Post-hoc analysis: Vitamin D versus placebo, Outcome 4 Hip bone mineral density (% change).
[Analysis 2.5]
Analysis 2.5. Comparison 2 Post-hoc analysis: Vitamin D versus placebo, Outcome 5 Distal forearm bone mineral density (% change).
[Analysis 2.6]
Analysis 2.6. Comparison 2 Post-hoc analysis: Vitamin D versus placebo, Outcome 6 Hip bone mineral density (change).