Intervention Review

You have free access to this content

Prophylactic antibiotics for penetrating abdominal trauma

  1. Martin Brand1,*,
  2. Andrew Grieve2

Editorial Group: Cochrane Injuries Group

Published Online: 18 NOV 2013

Assessed as up-to-date: 16 JAN 2013

DOI: 10.1002/14651858.CD007370.pub3

How to Cite

Brand M, Grieve A. Prophylactic antibiotics for penetrating abdominal trauma. Cochrane Database of Systematic Reviews 2013, Issue 11. Art. No.: CD007370. DOI: 10.1002/14651858.CD007370.pub3.

Author Information

  1. 1

    University of the Witwatersrand, Department of Surgery, Johannesburg, South Africa

  2. 2

    University of the Witwatersrand, General Surgery/Trauma Unit, Johannesburg, Gauteng, South Africa

*Martin Brand, Department of Surgery, University of the Witwatersrand, Johannesburg, 2109, South Africa.

Publication History

  1. Publication Status: New search for studies and content updated (no change to conclusions)
  2. Published Online: 18 NOV 2013



Additional references

Egger 1997
  • Egger M, Davey SA, Schneider M, Minder C. Bias in a meta-analysis detected by a simple, graphical test. BMJ (Clinical Research Edition) 1997;315(7109):629-34.
Fullen 1972
Greenland 1985
Handbook 2008
  • Higgins JPT, Green S (editors). Cochrane Handbook for Systematic Reviews of Interventions. Version 5.0.1 [updated September 2008]. The Cochrane Collaboration, 2008. Available from
Higgins 2002
Kjaergard 2001
  • Kjaergard LL, Villumsen J, Gluud C. Reported methodological quality and discrepancies between large and small randomised trials in meta-analyses. Annals of Internal Medicine 2001;135:982-9.
Luchette 2000
  • Luchette FA, Borzotta AP, Croce MA, O'Neill PA, Whittmann DH, Mullins CD, et al. Practice management guidelines for prophylactic antibiotic use in penetrating abdominal trauma: the EAST Practice Management Guidelines Work Group. Journal of Trauma 2000;48(3):508-18.
Macaskill 2001
Mantel 1959
Moher 1998
Poole 1944
  • Poole LT. Army progress with penicillin. British Journal of Surgery 1944;32:110-1.
    Direct Link:
Review Manager 2008
  • The Nordic Cochrane Centre, The Cochrane Collaboration. Review Manager (RevMan). 5.0 for Windows. Copenhagen: The Nordic Cochrane Centre, The Cochrane Collaboration, 2008.
Schulz 1995
  • Schulz KF, Chalmers I, Hayers RJ, Altman DG. Empirical evidence of bias. Dimensions of methodological quality associated with estimates of treatment effects in controlled trials. JAMA 1995;273:408-12.
Scott 1954
  • Scott R. Care of the battle casualty in advance of the aid station. Walter Reed Army Medical Centre Conference on recent advances in medicine and surgery. 19 April 1954.
Thadepalli 1972
  • Thadepalli H, Gorbach SL, Broido P, Norsen J. A prospective study of infections in penetrating abdominal trauma. American Journal of Clinical Nutrition 1972;25(12):1405-8.
Thadepalli 1973