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Probiotics for treating persistent diarrhoea in children

  1. Guillermo Bernaola Aponte1,*,
  2. Carlos Alfonso Bada Mancilla2,
  3. Nilton Yhuri Carreazo3,
  4. Raúl Alberto Rojas Galarza4

Editorial Group: Cochrane Infectious Diseases Group

Published Online: 20 AUG 2013

Assessed as up-to-date: 13 DEC 2012

DOI: 10.1002/14651858.CD007401.pub3


How to Cite

Bernaola Aponte G, Bada Mancilla CA, Carreazo NY, Rojas Galarza RA. Probiotics for treating persistent diarrhoea in children. Cochrane Database of Systematic Reviews 2013, Issue 8. Art. No.: CD007401. DOI: 10.1002/14651858.CD007401.pub3.

Author Information

  1. 1

    Suárez Angamos Hospital, Lima, Peru

  2. 2

    Emergencias Pediátricas Hospital, Lima, Peru

  3. 3

    Universidad Peruana de Ciencias Aplicadas, Escuela de Medicina, Lima, Peru

  4. 4

    Instituto Nacional de Salud del Niño (Children's Hospital of Lima), Lima, Peru

*Guillermo Bernaola Aponte, Suárez Angamos Hospital, Angamos Este Avenue 261, Miraflores, Lima, 18, Peru. guiber0307@hotmail.com. guiber37@yahoo.es.

Publication History

  1. Publication Status: New search for studies and content updated (no change to conclusions)
  2. Published Online: 20 AUG 2013

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References

References to studies included in this review

  1. References to studies included in this review
  2. References to studies excluded from this review
  3. Additional references
Basu 2007 {published data only}
  • Basu S, Chatterjee M, Ganguly S, Chandra PK. Effect of lactobacillus rhamnosus GG in persistent diarrhea in indian children. Journal of Clinical Gastroenterology 2007;41(8):756-60.
Castañeda 1995 {published and unpublished data}
  • Castañeda GC, García BE, Santa Cruz DM, Fernandez GM, Monterrey GP. Effects of saccharomyces boulardii in children with chronic diarrhea, especially cases due to giardiasis. Revista Mexicana de Puericultura y Pediatría 1995;2(12):1-11.
Gaón 2003 {published and unpublished data}
  • Gaon D, Garcia H, Winter L, Rodriguez N, Quintas R, Gonzales SN, Oliver G. Effect of lactobacillus strains and saccharomyces boulardii on persistent diarrhea in children. Medicina 2003;63(4):293-98.
Touhami 1992 {published and unpublished data}
  • Touhami M, Boudraa G, Mary JY, Soltana R, Desjeux JF. Clinical effects of substitution of yogurt for milk in persistent infantile diarrhea. Annales de Pediatrie 1992;39(2):79-86.

References to studies excluded from this review

  1. References to studies included in this review
  2. References to studies excluded from this review
  3. Additional references
Balli 1992 {published data only}
  • Balli F, Bertoïani P, Giberti G, Amarri S. High dose oral bacteriotherapy in chronic non specific diarrhea in infancy. Pediatria Medica e Chirurgica 1992;14(1):13-6.
Boudraa 1990 {published data only}
  • Boudraa G, Touhami M, Pochart P, Soltana R, Mary JY, Desjeux JF. Effect of feeding yogurt versus milk in children with persistent diarrhoea. Journal of Pediatric Gastroenterology and Nutrition 1990;11(4):509-12.
Chouraqui 1995 {unpublished data only}
  • Chouraqui JP, Dietsch J, Musial C, Blehaut, H. Saccharomyces boulardii (SB) in the management of toddler diarrhea: a double blind-placebo controlled study [abstract]. Journal of Pediatric Gastroenterology and Nutrition 1995;20(4):463.
Dinleyici 2011 {published data only}
  • Dinleyici EC, Eren M, Dogan N, Reyhanioglu S, Yargic ZA, Vandenplas Y. Clinical efficacy of Saccharomyces boulardii or metronidazole in symptomatic children with Blastocystis hominis infection. Parasitology research 2011;3:541-45.
Locascio 2002 {published data only}
  • Locascio M, Gonzáles S, Apella MC, Bru de Labanda E, Oliver G. Probiotic bacteriotherapy in chronic infantile diarrhea. Interciencia 2002;27(7):365-68.
Roggero 1990 {published data only}
  • Roggero P, Volpe C, Ceccatelli MP, Lambri A, Giuliani MG, Donattini T, Garavaglia MC, De Vincentiis A. Crystalline lactulose and oral preparation of micro-organisms as treatment for aspecific chronic diarrhea in infants. Minerva Pediatrica 1990;42(4):147-50.

Additional references

  1. References to studies included in this review
  2. References to studies excluded from this review
  3. Additional references
Allen 2003
  • Allen SJ, Okoko B, Martinez E, Gregorio G, Dans LF. Probiotics for treating infectious diarrhoea. Cochrane Database of Systematic Reviews 2003, Issue 3. [DOI: 10.1002/14651858.CD003048.pub2]
Anonymous 1988
  • Anonymous. Persistent diarrhoea in children in developing countries: memorandum from a WHO Meeting. Bulletin of the World Health Organization 1988;66(6):709-17.
Bhandari 1989
Bhutta 2004
  • Bhutta ZA, Ghishan F, Lindley K, Memon IA, Mittal S, Rhoads JM, Commonwealth Association of Paediatric Gastroenterology and Nutrition. Persistent and chronic diarrhea and malabsorption: Working Group report of the second World Congress of Pediatric Gastroenterology, Hepatology, and Nutrition. Journal of Pediatric Gastroenterology and Nutrition 2004;39 Suppl 2:711-6.
Boirivant 2007
Fauveau 1992
Higgins 2008
  • Higgins JPT, Altman DG (editors). Chapter 8: Assessing risk of bias in included studies. In: Higgins JPT, Green S (editors), Cochrane Handbook of Systematic Reviews of Intervention. Version 5.0.0 (updated February 2008). The Cochrane Collaboration, 2008. Available from www.cochrane-handbook.org.
Huang 2002
IWGPD 1996
  • International Working Group on Persistent Diarrhoea. Evaluation of an algorithm for the treatment of persistent diarrhoea: a multicentre study. Bulletin of the World Health Organization 1996;74(5):479-89.
Lefebvre 2008
  • Lefebvre C, Manheimer E, Glanville J. Chapter 6: Searching for studies. In: Higgins JPT, Green S (editors). Cochrane Handbook for Systematic Reviews of Interventions Version 5.0.0 (updated February 2008). The Cochrane Collaboration, 2008. Available from www.cochrane-handbook.org.
McFarland 2006
  • McFarland LV, Elmer GW, McFarland M. Meta-analysis of probiotics for the prevention and treatment of acute pediatric diarrhea. International Journal of Probiotics and Prebiotics 2006;1(1):63-76.
Ochoa 2004
  • Ochoa TJ, Salazar-Lindo E, Cleary TG. Management of children with infection-associated persistent diarrhea. Seminars in Pediatric Infectious Diseases 2004;15(4):229-36.
Pineiro 2007
  • Pineiro M, Stanton C. Probiotic bacteria: legislative framework-- requirements to evidence basis. Journal of Nutrition 2007;137(3 Suppl 2):850-3.
Review Manager 5 [Computer program]
  • The Nordic Cochrane Centre, The Cochrane Collaboration. Review Manager (RevMan). Version 5.0. Copenhagen: The Nordic Cochrane Centre, The Cochrane Collaboration, 2008.
Schorling 1990
  • Schorling JB, Wanke CA, Schorling SK, Mcauliffe JF, de Souza MA, Guerrant RL. A prospective study of persistent diarrhea among children in an urban Brazilian slum. Patterns of occurrence and etiologic agents. American Journal of Epidemiology 1990;132(1):144-56.
Szajewska 2001
  • Szajewska H, Mrukowicz JZ. Probiotics in the treatment and prevention of acute infectious diarrhea in infants and children: a systematic review of published randomized, double-blind, placebo-controlled trials. Journal of Pediatric Gastroenterology and Nutrition 2001;33 Suppl 2:17-25.
Szajewska 2005
  • Szajewska H, Mrukowicz JZ. Use of probiotics in children with acute diarrhea. Paediatric Drugs 2005;7(2):111-22.
Van Niel 2002