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Corticosteroids as adjuvant therapy for ocular toxoplasmosis

  1. Smitha Jasper1,
  2. Satyanarayana S Vedula2,
  3. Sheeja S John1,
  4. Saban Horo1,
  5. Yasir J Sepah3,
  6. Quan Dong Nguyen3,*

Editorial Group: Cochrane Eyes and Vision Group

Published Online: 30 APR 2013

Assessed as up-to-date: 11 OCT 2012

DOI: 10.1002/14651858.CD007417.pub2


How to Cite

Jasper S, Vedula SS, John SS, Horo S, Sepah YJ, Nguyen QD. Corticosteroids as adjuvant therapy for ocular toxoplasmosis. Cochrane Database of Systematic Reviews 2013, Issue 4. Art. No.: CD007417. DOI: 10.1002/14651858.CD007417.pub2.

Author Information

  1. 1

    Christian Medical College, Department of Ophthalmology, Vellore, Tamil Nadu, India

  2. 2

    Johns Hopkins University, Baltimore, Maryland, USA

  3. 3

    University of Nebraska Medical Center, Stanley M. Truhlsen Eye Institute, Omaha, Nebraska, USA

*Quan Dong Nguyen, Stanley M. Truhlsen Eye Institute, University of Nebraska Medical Center, Omaha, Nebraska, USA. quan.nguyen@unmc.edu.

Publication History

  1. Publication Status: Edited (no change to conclusions)
  2. Published Online: 30 APR 2013

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References

References to studies excluded from this review

  1. References to studies excluded from this review
  2. Additional references
Acers 1964 {published data only}
  • Acers TE. Toxoplasmosis retinochoroiditis: a double blind therapeutic study. Archives of Ophthalmology 1964;71(1):58-62.
Apt 1978 {published data only}
Arseni 1979 {published data only}
  • Arseni C, Ciurea V, Horvath L. Possibilities of preventing and combating congenital toxoplasmosis. Revista De Medicina-Interna, Neurologie, Psihiatrie, Neurochirurgie, Dermato-Venerologie 1979;24(4):251-7.
Atias 1966 {published data only}
  • Atías A, Pasmanik S, Niedmann G. An analysis of the treatment and evolution of 56 cases of ocular toxoplasmosis. Boletin Chileno De Parasitologia 1966;21(4):108-11.
Bethge 1971 {published data only}
  • Bethge H. Alternating corticoid therapy. Deutsche Medizinische Wochenschrift 1971;96(30):1254-9.
Bosch-Driessen 1988 {published data only}
  • Bosch-Driessen EH, Rothova A. Sense and nonsense of corticosteroid administration in the treatment of ocular toxoplasmosis. British Journal of Ophthalmology 1998;82(8):858-60.
Bouree 1997 {published data only}
  • Bouree P, Romand S, Majoube A. Liver transplantation and toxoplasmosis: Serological follow-up of 34 patients [Transplantation hepatique et toxoplasmose: Suivi serologique de 34 patients]. Medecine et Chirurgie Digestives 1997;26(4):173-4.
Coles 1966 {published data only}
  • Coles RS. Steroid therapy in uveitis. International Ophthalmology Clinics 1966;6(4):869-901.
Concha 2000 {published data only}
  • Concha M, Rabinstein A. Central nervous system opportunistic infections in HIV-1 infection. CNS Spectrums 2000;5(4):43-60.
Couvreur 1983 {published data only}
Couvreur 1985 {published data only}
  • Couvreur J, Bloch-Michel E. Ocular toxoplasmosis: preventive and therapeutic measures. Medecine et Hygiene 1985;43(1616):2216-20.
Djurkovic-Djakovic 1995 {published data only}
  • Djurkovic-Djakovic O, Stanojevic-Paovic A, Bobic B, Bergam J, Nikolic A, Paovic J, et al. Short-term effects of the clindamycin-steroid regimen in the treatment of ocular toxoplasmosis. Journal of Chemotherapy 1995;7 Suppl 4:199-201.
Giles 1966 {published data only}
Gordon 1970 {published data only}
  • Gordon DM. The treatment of toxoplasmic uveitis. International Ophthalmology Clincs 1970;10(3):639-46.
Hay 1997 {published data only}
  • Hay J, Dutton GN. How should active toxoplasmic retinochoroiditis be treated?. Eye 1997;11(Pt 6):767-70.
Nolan 1968 {published data only}
O'Connor 1974 {published data only}
O'Connor 1976 {published data only}
  • O'Connor GR, Frenkel JK. Dangers of steroid treatment in toxoplasmosis. Periocular injections and systemic therapy. Archives of Ophthalmology 1976;94(2):213.
Reibaldi 1989 {published data only}
  • Reibaldi A, Cavallaro N, Santocono M, Scuderi A. Up-date on the treatment of ocular toxoplasmosis. Journal of Chemotherapy 1989;1 Suppl 4:954-6.
Sherman 1992 {published data only}
  • Sherman MD, Nozik RA. Other infections of the choroid and retina. Toxoplasmosis, histoplasmosis, Lyme disease, syphilis, tuberculosis and ocular toxocariasis. Infectious Disease Clinics of North America 1992;6(4):893-908.
Unknown author 1968 {published data only}
  • Anonymous. Toxoplasmosis. Medical Letter on Drugs and Therapeutics 1968;10(26):107-8.

Additional references

  1. References to studies excluded from this review
  2. Additional references
Acers 1958
  • Acers TE. Toxoplasmic retinochoroiditis: a double blind therapeutic study. Archives of Ophthalmology 1958;71(1):58-62.
Anderson 1979
  • Anderson S. Toxoplasma gondii. In: Mandell Gl, Douglas RG Jr, Bennet JE editor(s). Principles and Practice of Infectious Diseases. New York: John Wiley and Sons, 1979.
Benzina 2005
  • Benzina Z, Chaabouni S, Hentati N, Trigui A, Chaabouni F, Ben Salah S, et al. Recurrent toxoplasmic retinochoroiditis after clindamycin treatment. Journal Francais d'Ophthalmologie 2005;28(9):958-64.
Bloch-Michel 1987
  • Bloch-Michel E, Nussenblatt RB. International Uveitis Study Group recommendations for the evaluation of intraocular inflammatory disease. American Journal of Ophthalmology 1987;103(2):234-5.
Bosch-Driessen 2002
  • Bosch-Driessen LH, Verbraak FD, Suttorp-Schulten MS, van Ruyven RL, Klok AM, Hoyng CB, et al. A prospective, randomized trial of pyrimethamine and azithromycin vs pyrimethamine and sulfadiazine for the treatment of ocular toxoplasmosis. American Journal of Ophthalmology 2002;134(1):34-40.
Damms 1993
  • Damms T, Bohnke M, Behrend-Berdin B. Results of therapy in ocular toxoplasmosis. Comparison of various forms of therapy. Ophthalmologe 1993;90(6):737-41.
Dodds 2008
  • Dodds EM, Holland GN, Stanford MR, Yu F, Siu WO, International Ocular Toxoplasmosis Research Group. Intraocular inflammation associated with ocular toxoplasmosis: relationships at initial examination. American Journal of Ophthalmology 2008;146(6):856-65.
Fine 1981
  • Fine SL, Owens SL, Haller JA, Knox DL, Patz A. Choroidal neovascularization as a late complication of ocular toxoplasmosis. American Journal of Ophthalmology 1981;91(3):318-22.
Folk 1984
  • Folk JC, Lobes LA. Presumed toxoplasmis papillitis. Ophthalmology 1984;91(1):64-7.
Gilbert 1999
  • Gilbert RE, Dunn DT, Lightman S, Murray PI, Pavesio CE, Gormley PD, et al. Incidence of symptomatic toxoplasma eye disease: aetiology and public health implications. Epidemiology and Infection 1999;123(2):283-9.
Gilbert 2002
  • Gilbert RE, Harden M, Stanford MR. Antibiotics versus control for toxoplasma retinochoroiditis. Cochrane Database of Systematic Reviews 2002, Issue 1. [DOI: 10.1002/14651858.CD002218]
Glanville 2006
  • Glanville JM, Lefebvre C, Miles JN, Camosso-Stefinovic J. How to identify randomized controlled trials in MEDLINE: ten years on. Journal of the Medical Library Association 2006;94(2):130-6.
Guldsten 1983
  • Guldsten H. Clindamycin and sulphonamides in the treatment of ocular toxoplasmosis. Acta Ophthalmologica 1983;61(1):51-7.
Hegab 2003
Higgins 2011a
  • Higgins JPT, Altman DG, Sterne JAC (editors). Chapter 8: Assessing risk of bias in included studies. In: Higgins JPT, Green S (editors). Cochrane Handbook for Systematic Reviews of Interventions Version 5.1.0 (updated March 2011). The Cochrane Collaboration, 2011. Available from www.cochrane-handbook.org.
Higgins 2011b
  • Higgins JPT, Deeks JJ, Altman DG (editors). Chapter 16: Special topics in statistics. In: Higgins JPT, Green S (editors). Cochrane Handbook for Systematic Reviews of Interventions Version 5.1.0 (updated March 2011). The Cochrane Collaboration, 2011. Available from www.cochrane-handbook.org.
Hogan 1959
Holland 2002
Kaufman 1960
Kim 2012
  • Kim SJ, Scott IU, Brown GC, Brown MM, Ho AC, Ip MS, et al. Interventions for toxoplasma retinochoroiditis: a report by the American Academy of Ophthalmology. Ophthalmology 2013;120(2):371-8.
Kishore 2001
  • Kishore K, Conway MD, Peyman GA. Intravitreal clindamycin and dexamethasone for toxoplasmic retinochoroiditis. Ophthalmic Surgery and Lasers 2001;32(3):183-92.
Klaren 2002
Lam 1993
Lum 2005
  • Lum F, Jones JL, Holland GN, Liesegang TJ. Survey of ophthalmologists about ocular toxoplasmosis. American Journal of Ophthalmology 2005;140(4):724-6.
Mittelviefhaus 1992
Nozik 1977
  • Nozik RA. Results of treatment of ocular toxoplasmosis with injectable corticosteroids. Transactions. Section on Ophthalmology. American Academy of Ophthalmology and Otolaryngology 1977;83(5):811-8.
Nussenblatt 1985
  • Nussenblatt RB, Palestine AG, Chan CC, Roberge F. Standardization of vitreal inflammatory activity in intermediate and posterior uveitis. Ophthalmology 1985;92(4):467-71.
Papadia 2011
  • Papadia M, Aldigeri R, Herbort CP. The role of serology in active ocular toxoplasmosis. International Ophthalmology 2011;31(6):461-5.
Parmar 1998
Psilas 1990
  • Psilas K, Petroutsos G, Aspiotis M. Treatment of toxoplasmosis. The treatment of toxoplasmic chorioretinitis. Journal Francais d'Ophthalmologie 1990;13(11-12):551-3.
Raskin 2002
  • Raskin E, Alves M, Eredia GC, Raskin A, Ruiz Alves M. Ocular toxoplasmosis: A comparative study of the treatment with sulfadiazine and pyrimetamine versus sulphametoxazole-trimethoprim. Revista Brasileira De Oftalmologia 2002;61(5):335-8.
Rothova 1989
Rush 2012
  • Rush R, Sheth S. Fulminant toxoplasmic retinochoroiditis following Intravitreal triamcinolone administration. Indian Journal of Ophthalmology 2012;60(2):141-3.
Sabates 1981
Soheilian 2005
  • Soheilian M, Sadoughi MM, Ghajarnia M, Deghan MH, Behboudi H, Anisian A, et al. Prospective randomized trial of trimethoprim/sulfamethoxazole versus pyrimethamine and sulfadiazine in the treatment of ocular toxoplasmosis. Ophthalmology 2005;112(11):1876-82.
Timsit 1987
  • Timsit JC, Bloch-Michel E. Efficacy of specific chemotherapy in the prevention of recurrences of toxoplasmic chorioretinitis during the 4 years following the treatment. Journal Francais d'Opthalmologie 1987;10(1):15-23.