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Intrapartum antibiotics for known maternal Group B streptococcal colonization

  1. Arne Ohlsson1,*,
  2. Vibhuti S Shah2

Editorial Group: Cochrane Pregnancy and Childbirth Group

Published Online: 10 JUN 2014

DOI: 10.1002/14651858.CD007467.pub4


How to Cite

Ohlsson A, Shah VS. Intrapartum antibiotics for known maternal Group B streptococcal colonization. Cochrane Database of Systematic Reviews 2014, Issue 6. Art. No.: CD007467. DOI: 10.1002/14651858.CD007467.pub4.

Author Information

  1. 1

    University of Toronto, Departments of Paediatrics, Obstetrics and Gynaecology and Institute of Health Policy, Management and Evaluation, Toronto, ON, Canada

  2. 2

    University of Toronto, Department of Paediatrics and Institute of Health Policy, Management and Evaluation, Toronto, ON, Canada

*Arne Ohlsson, Departments of Paediatrics, Obstetrics and Gynaecology and Institute of Health Policy, Management and Evaluation, University of Toronto, 600 University Avenue, Toronto, ON, M5G 1X5, Canada. aohlsson@mtsinai.on.ca.

Publication History

  1. Publication Status: Edited (no change to conclusions), comment added to review
  2. Published Online: 10 JUN 2014

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References

References to studies included in this review

  1. References to studies included in this review
  2. References to studies excluded from this review
  3. Additional references
  4. References to other published versions of this review
Boyer 1986 {published data only}
  • Boyer KM, Gadzala CA, Kelly PC, Gotoff SP. Ampicillin prophylaxis of group B streptococcal transmission in high-risk parturient women. Pediatric Research 1982;16:280A.
  • Boyer KM, Gadzala CA, Kelly PD, Gotoff SP. Selective intrapartum chemoprophylaxis of neonatal group B streptococcal early-onset disease. III. Interruption of mother-to-infant transmission. Journal of Infectious Diseases 1983;148:810-6.
  • Boyer KM, Gotoff SP. Prevention of early-onset neonatal group B streptococcal disease with selective intrapartum chemoprophylaxis. New England Journal of Medicine 1986;314:1665-9.
  • Gotoff SP. Chemoprophylaxis of early onset group B streptococcal disease. Pediatric Infectious Disease 1984;3(5):401-3.
Edwards 2002a {published data only}
  • Edwards R, Clark P, Duff P. Intrapartum antibiotic prophylaxis with either penicillin or ampicillin may increase the rate of neonatal sepsis caused by ampicillin-resistant Gram-negative bacteria. American Journal of Obstetrics and Gynecology 2001;185:S190.
  • Edwards RK, Clark P, Sistrom CL, Duff P. Intrapartum antibiotic prophylaxis 1: relative effects of recommended antibiotics on Gram-negative pathogens. Obstetrics & Gynecology 2002;100:534-9.
Matorras 1990 {published data only}
  • Matorras R, Garcia-Perea A, Omenaca F, Diez-Enciso M, Madero R, Usandizaga JA. Intrapartum chemoprophylaxis of early-onset group B streptococcal disease. European Journal of Obstetrics & Gynecology and Reproductive Biology 1991;40(1):57-62.
  • Mattoras R, Garcia-Perea A, Madero R, Usandizaga JA. Maternal colonization by group B streptococci and puerperal infection; analysis of intrapartum chemoprophylaxis. European Journal of Obstetrics & Gynecology and Reproductive Biology 1990;38(3):203-7.
  • Omenaca Teres F, Matorras R, García Perea A, Elorza MD. Prevention of neonatal group B streptococcal sepsis. Pediatric Infectious Disease Journal 1987;6(9):874.
Tuppurainen 1989 {published data only}
  • Tuppurainen N, Hallman M. Prevention of neonatal group B streptococcal disease: intrapartum detection and chemoprophylaxis of heavily colonized parturients. Obstetrics & Gynecology 1989;75:583-7.
  • Tuppurainen N, Österlund K, Hallman M. Selective intrapartum penicillin prophylaxis of early onset group B streptococcal disease. Pediatric Research 1986;20(4 Pt 2):403A.

References to studies excluded from this review

  1. References to studies included in this review
  2. References to studies excluded from this review
  3. Additional references
  4. References to other published versions of this review
Belady 1996 {published data only}
  • Belady P, Graham S, Lesotte D, Merenstein G, Gibbs R. Does the use of ampicillin versus penicillin for the prevention of neonatal group B streptococcal (GBS) infection result in higher rates of colonization with resistant organisms?. Infectious Diseases in Obstetrics and Gynecology 1996;4:54.
  • Davies JK, Barrenachea J, Mackenzie T, Gibbs RS. Maternal infections following intrapartum GBS prophylaxis. Infectious Diseases in Obstetrics and Gynecology 1998;6(2):80.
Dykes 1987 {published data only}
  • Dykes AK, Christensen KK, Christensen P. Chlorhexidine for prevention of neonatal colonization with group B streptococci. IV. Depressed puerperal carriage following vaginal washing with chlorhexidine during labour. European Journal of Obstetrics & Gynecology and Reproductive Biology 1987;24:293-7.
Easmon 1983 {published data only}
Facchinetti 2002 {published data only}
  • Facchinetti F, Piccinini F, Mordini B. Prophylaxis of group B streptococcus vertical transmission by using vaginal chlorhexidine. American Journal of Obstetrics and Gynecology 1999;180(1 Pt 2):S84.
  • Facchinetti F, Piccinini F, Mordini B, Volpe A. Chlorhexidine vaginal flushings versus systemic ampicillin in the prevention of vertical transmission of neonatal group B streptococcus, at term. Journal of Maternal-Fetal and Neonatal Medicine 2002;11:84-8.
Gibbs 1996 {published data only}
  • Gibbs RS, McNabb F. Randomized clinical trial of intrapartum clindamycin cream for reduction of group B streptococcal maternal and neonatal colonization. Infectious Diseases in Obstetrics and Gynecology 1996;4(1):25-7.
Håkansson 2014 {published data only}
  • Håkansson S, Kāllén K, Bullarbo M, Holmgren P-Å, Bremme K, Larsson Å, et al. Real-time PCR-assay in the delivery suite for determination of group B streptococcal colonization in a setting with risk-based antibiotic prophylaxis. Journal of Maternal-Fetal & Neonatal Medicine 2014;27(4):328-32.
Merenstein 1980 {published data only}
  • Merenstein GB, Todd WA, Brown G, Yost CC, Luzier T. Group B beta-hemolytic streptococcus: randomized controlled treatment study at term. Obstetrics & Gynecology 1980;55(3):315-8.
Morales 1986 {published data only}
  • Lim DV, Morales WJ, Walsh AF, Kazaniz D. Reduction of morbidity and mortality rates for neonatal group B streptococcal disease through early diagnosis and chemoprophylaxis. Journal of Clinical Microbiology 1986;23:489-92.
  • Morales WJ, Lim DV, Walsh AF. Prevention of neonatal group B streptococcal sepsis by the use of a rapid screening test and selective intrapartum prophylaxis. American Journal of Obstetrics and Gynecology 1986;155:979-83.
Pinette 2005 {published data only}
  • Pinette M, Thayer K, Wax J, Blackstone J, Cartin A. Efficacy of intramuscular penicillin in the eradication of group b streptococcal colonization at delivery. American Journal of Obstetrics and Gynecology 2003;189(6 Suppl 1):S96.
  • Pinette MG, Thayer K, Wax JR, Blackstone J, Cartin A. Efficacy of intramuscular penicillin in the eradication of group B streptococcal colonization at delivery. Journal of Maternal-Fetal and Neonatal Medicine 2005;17(5):333-5.
Sáez-Llorens 1995 {published data only}
  • Sáez-Llorens X, Ah-Chu MS, Castaňo E, Cortés L, Torres A, Suárez M, et al. Intrapartum prophylaxis with ceftriaxone decreases rates of bacterial colonization and early-onset infection in newborns. Clinical Infectious Diseases 1995;21(4):876-80.

Additional references

  1. References to studies included in this review
  2. References to studies excluded from this review
  3. Additional references
  4. References to other published versions of this review
AAP 1992
  • American Academy of Pediatrics, Committee on Infectious Diseases and Committee on Fetus and Newborn. Guidelines for prevention of group B streptococcal infection by chemoprophylaxis. Pediatrics 1992;90:775-8.
AAP 1997
  • American Academy of Pediatrics, Committee on Infectious Diseases/Committee on Fetus and Newborn. Revised guidelines for prevention of early-onset group B streptococcal (GBS) disease. Pediatrics 1997;99:489-96.
Abdelazim 2013
Ablow 1976
  • Ablow RC, Driscoll SG, Effman EL, Gross I, Jolles CJ, Uauy R, et al. A comparison of early-onset group B streptococcal neonatal infection and the respiratory distress syndrome of the newborn. New England Journal of Medicine 1976;294:65-70.
ACOG 1992
  • Committee on Technical Bulletins of the American College of Obstetricians and Gynecologists. Group B streptococcal infections in pregnancy. ACOG Technical Bulletin no. 170. ACOG, July 1992.
ACOG 1996
  • American College of Obstetricians and Gynecologists, Committee on Obstetric Practice. Prevention of early-onset group B streptococcal disease in newborns [Opinion 173]. Washington DC: American College of Obstetricians and Gynecologists, 1996.
Akker van Marle 2005
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Allardice 1982
  • Allardice JG, Baskett TF, Seshia MMK, Bowman N, Malazdrewicz R. Perinatal group B streptococcal colonization and infection. American Journal of Obstetrics and Gynecology 1982;142:617-20.
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Boyer 1983
  • Boyer KM, Gadzala CA, Kelly PD, Gotoff SP. Selective intrapartum chemoprophylaxis of neonatal group B streptococcal early-onset disease. III. Interruption of mother-to-infant transmission. Journal of Infectious Diseases 1983;148:810-6.
Carbonell-Estrany 2008
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Cayeux 1972
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Davies 1998
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Dillon 1987
Dinsmoor 2005
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Edwards 2002b
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Eickhoff 1964
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Group B Strep Association 2008
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McNanley 2007
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References to other published versions of this review

  1. References to studies included in this review
  2. References to studies excluded from this review
  3. Additional references
  4. References to other published versions of this review
Ohlsson 2009
Ohlsson 2013
Smaill 1992
  • Smaill F. Intrapartum antibiotics for Group B streptococcal colonisation. Oxford database of perinatal trials 1992; Vol. Version 1.3, Disk Issue 7:Record 3006.
Smaill 1996