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Vitamin A supplementation for the prevention of morbidity and mortality in infants six months of age or less

  1. Siddhartha Gogia1,*,
  2. Harshpal S Sachdev2

Editorial Group: Cochrane Neonatal Group

Published Online: 5 OCT 2011

Assessed as up-to-date: 29 NOV 2010

DOI: 10.1002/14651858.CD007480.pub2


How to Cite

Gogia S, Sachdev HS. Vitamin A supplementation for the prevention of morbidity and mortality in infants six months of age or less. Cochrane Database of Systematic Reviews 2011, Issue 10. Art. No.: CD007480. DOI: 10.1002/14651858.CD007480.pub2.

Author Information

  1. 1

    Max Hospital, Pediatrics, Gurgaon, Haryana, India

  2. 2

    Sitaram Bhartia Institute of Science and Research, Pediatrics and Clinical Epidemiology, New Delhi, India

*Siddhartha Gogia, Pediatrics, Max Hospital, Gurgaon, Haryana, India. gogiasiddhartha@gmail.com.

Publication History

  1. Publication Status: New
  2. Published Online: 5 OCT 2011

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[Figure 1]
Figure 1. Risk of bias summary: review authors' judgements about each risk of bias item for each included study.
[Figure 2]
Figure 2. Funnel plot of comparison: Maternal vitamin A supplementation versus placebo, outcome: 1.1.1 Mortality in the first year of life for the main analysis.
[Figure 3]
Figure 3. Funnel plot of comparison: 2 Young Infant vitamin A supplementation versus placebo, outcome: 2.1.1 Mortality in the first year of life for the main analysis.
[Figure 4]
Figure 4. Forest plot for all cause mortality during infancy following maternal postpartum supplementation of Vitamin A after including HIV positive mothers also. The report Humphrey 2006 also includes the data for HIV negative mothers from Malaba 2005.
[Figure 5]
Figure 5. Forest plot for all cause mortality during the first year of life following vitamin A supplementation from birth to six months of age including participants born to HIV positive mothers. Random-effects model estimate was used for pooling.
[Analysis 1.1]
Analysis 1.1. Comparison 1 Maternal vitamin A supplementation versus placebo, Outcome 1 Mortality in the first year of life.
[Analysis 1.2]
Analysis 1.2. Comparison 1 Maternal vitamin A supplementation versus placebo, Outcome 2 Mortality in the first month of life.
[Analysis 1.3]
Analysis 1.3. Comparison 1 Maternal vitamin A supplementation versus placebo, Outcome 3 Cause specific mortality in the first year of life.
[Analysis 2.1]
Analysis 2.1. Comparison 2 Young infant vitamin A supplementation versus placebo, Outcome 1 Mortality in the first year of life.
[Analysis 2.2]
Analysis 2.2. Comparison 2 Young infant vitamin A supplementation versus placebo, Outcome 2 Mortality in the first month of life.
[Analysis 2.3]
Analysis 2.3. Comparison 2 Young infant vitamin A supplementation versus placebo, Outcome 3 Cause specific mortality in the first year of life.
[Analysis 2.4]
Analysis 2.4. Comparison 2 Young infant vitamin A supplementation versus placebo, Outcome 4 Morbidity in the first year of life.
[Analysis 2.5]
Analysis 2.5. Comparison 2 Young infant vitamin A supplementation versus placebo, Outcome 5 Adverse effects of vitamin A supplementation.