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Single dose oral dexibuprofen [S(+)-ibuprofen] for acute postoperative pain in adults

  1. Sheena Derry*,
  2. Jessica Best,
  3. R Andrew Moore

Editorial Group: Cochrane Pain, Palliative and Supportive Care Group

Published Online: 23 OCT 2013

Assessed as up-to-date: 22 AUG 2013

DOI: 10.1002/14651858.CD007550.pub3


How to Cite

Derry S, Best J, Moore RA. Single dose oral dexibuprofen [S(+)-ibuprofen] for acute postoperative pain in adults. Cochrane Database of Systematic Reviews 2013, Issue 10. Art. No.: CD007550. DOI: 10.1002/14651858.CD007550.pub3.

Author Information

  1. University of Oxford, Pain Research and Nuffield Department of Clinical Neurosciences, Oxford, Oxfordshire, UK

*Sheena Derry, Pain Research and Nuffield Department of Clinical Neurosciences, University of Oxford, Pain Research Unit, Churchill Hospital, Oxford, Oxfordshire, OX3 7LE, UK. sheena.derry@ndcn.ox.ac.uk.

Publication History

  1. Publication Status: New search for studies and content updated (no change to conclusions)
  2. Published Online: 23 OCT 2013

SEARCH

References

References to studies included in this review

  1. References to studies included in this review
  2. References to studies excluded from this review
  3. Additional references
  4. References to other published versions of this review
BR1160 1995 {unpublished data only}
  • Lancaster L, Goulder MA. A double blind, singe-dose, parallel-group study comparing the analgesic effect of S(+) ibuprofen with racemic ibuprofen and placebo following unilateral or bilateral extraction of third molars. Boots healthcare international, trial synopsis 1995:1-79.
Dionne 1998 {published data only}

References to studies excluded from this review

  1. References to studies included in this review
  2. References to studies excluded from this review
  3. Additional references
  4. References to other published versions of this review
Jamali 1999 {published data only}

Additional references

  1. References to studies included in this review
  2. References to studies excluded from this review
  3. Additional references
  4. References to other published versions of this review
Clarke 2012
Collins 1997
Collins 2001
Cook 1995
Cooper 1991
  • Cooper SA. Single-dose analgesic studies: the upside and downside of assay sensitivity. The Design of Analgesic Clinical Trials. Advances in Pain Research Therapy 1991;18:117-24.
Derry 2009
  • Derry C, Derry S, Moore RA, McQuay HJ. Single dose oral ibuprofen for acute postoperative pain in adults. Cochrane Database of Systematic Reviews 2009, Issue 3. [DOI: 10.1002/14651858.CD001548.pub2]
Derry 2010
  • Derry S, Moore RA, McQuay HJ. Single dose oral codeine, as a single agent, for acute postoperative pain in adults. Cochrane Database of Systematic Reviews 2010, Issue 4. [DOI: 10.1002/14651858.CD008099.pub2]
FitzGerald 2001
Gabard 1995
  • Gabard B, Nirnberger G, Schiel H, Mascher H, Kikuta C, Mayer JM. Comparison of the bioavailability of dexibuprofen administered alone or as part of racemic ibuprofen. European Journal of Clinical Pharmacology 1995;48(6):505-11.
Hawel 2003
  • Hawel R, Klein G, Singer F, Mayrhofer F, Kahler ST. Comparison of the efficacy and tolerability of dexibuprofen and celecoxib in the treatment of osteoarthritis of the hip. International journal of Clinical Pharmacology and Therapeutics 2003;41(4):153-64.
Higgins 2011
  • Altman DG, Antes G, Gøtzsche P, Higgins JPT, Jüni P, Lewis S, et al. Assessing risk of bias in included studies. In: Higgins JPT, Altman DG, Sterne JAC editor(s). Cochrane Handbook for Systematic Reviews of Interventions. Version 5.1.0 [updated March 2011]. www.cochrane-handbook.org. The Cochrane Collaboration, 2011.
Jadad 1996a
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Kollenz 2009
L'Abbé 1987
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McQuay 2005
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Moher 1999
Moore 1996
Moore 1997a
Moore 1997b
Moore 1998
Moore 2003
  • Moore RA, Edwards J, Barden J, McQuay HJ. Bandolier's Little Book of Pain. Oxford: Oxford University Press, 2003. [ISBN: 0-19-263247-7]
Moore 2005
Moore 2006
  • Moore A, McQuay H. Bandolier's Little Book of Making Sense of the Medical Evidence. Oxford: Oxford University Press, 2006. [ISBN: 0-19-856604-2]
Moore 2011a
Moore 2013a
Moore 2013b
  • Moore RA, Derry S, Straube S, Ireson-Pain J, Wiffen PJ. Faster, higher, stronger? Evidence for formulation and efficacy for ibuprofen in acute pain. Pain 2013;epub 14 August. [DOI: 10.1016/j.pain.2013.08.013]
Morris 1995
  • Morris JA, Gardner MJ. Calculating confidence intervals for relative risk, odds ratio and standardised ratios and rates. In: Gardner MJ, Altman DG editor(s). Statistics with Confidence - Confidence Intervals and Statistical Guidelines. London: British Medical Journal, 1995:50-63.
Nuesch 2010
PACT 2013
  • Prescription Cost Analysis, England 2012. London: Health and Social Care Information Centre, 2013. [ISBN: 978-1-84-636859-2]
Phleps 2001
  • Phleps W. Overview on clinical data of dexibuprofen. Clinical Rheumatology 2001;20(Suppl 1):S15-2.
RevMan 2012 [Computer program]
  • The Nordic Cochrane Centre, The Cochrane Collaboration. Review Manager (RevMan). Version 5.2. Copenhagen: The Nordic Cochrane Centre, The Cochrane Collaboration, 2012.
Singer 2000
  • Singer F, Mayrhofer F, Klein G, Hawel R, Kollenz CJ. Evaluation of the efficacy and dose-response relationship of dexibuprofen (S(+)-ibuprofen) in patients with osteoarthritis of the hip and comparison with racemic ibuprofen using the WOMAC osteoarthritis index. International Journal of Clinical Pharmacology and Therapeutics 2000;38(1):15-24.
Toms 2008
Zheng 2008
  • Zheng C, Hao H, Wang G, Sang G, Sun J, Li P, et al. Chiral separation of ibuprofen and chiral pharmacokinetics in healthy Chinese volunteers. European Journal of Drug Metabolism and Pharmacokinetics 2008;33(1):45-51.

References to other published versions of this review

  1. References to studies included in this review
  2. References to studies excluded from this review
  3. Additional references
  4. References to other published versions of this review
Moore 2009
  • Moore RA, Derry S, McQuay HJ. Single dose oral dexibuprofen [S(+)-ibuprofen] for acute postoperative pain in adults. Cochrane Database of Systematic Reviews 2009, Issue 3. [DOI: 10.1002/14651858.CD007550.pub2]