High-dose chemotherapy with autologous stem cell support for first-line treatment of aggressive non-Hodgkin lymphoma: a systematic review and meta-analysis based on individual patient data

  • Protocol
  • Intervention



This is the protocol for a review and there is no abstract. The objectives are as follows:

To determine the effectiveness of high-dose chemotherapy regimens plus autologous stem cell transplantation, with or without rituximab, for treating aggressive non-Hodgkin's lymphoma, and in specific subgroups of patients (prognostic groups) in comparison with a standard CHOP-like regimen, with or without rituximab.