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Pharmacotherapy for trichotillomania

  1. Rachel Rothbart1,
  2. Taryn Amos2,
  3. Nandi Siegfried2,
  4. Jonathan C Ipser2,
  5. Naomi Fineberg3,
  6. Samuel R Chamberlain4,
  7. Dan J Stein2,*

Editorial Group: Cochrane Common Mental Disorders Group

Published Online: 8 NOV 2013

Assessed as up-to-date: 31 JUL 2013

DOI: 10.1002/14651858.CD007662.pub2


How to Cite

Rothbart R, Amos T, Siegfried N, Ipser JC, Fineberg N, Chamberlain SR, Stein DJ. Pharmacotherapy for trichotillomania. Cochrane Database of Systematic Reviews 2013, Issue 11. Art. No.: CD007662. DOI: 10.1002/14651858.CD007662.pub2.

Author Information

  1. 1

    University of British Columbia, Department of Psychiatry, Vancouver, British Columbia, Canada

  2. 2

    University of Cape Town, Department of Psychiatry and Mental Health, Cape Town, South Africa

  3. 3

    Queen Elizabeth II Hospital, National Obsessive Compulsive Disorders Treatment Service, Welwyn Garden City, Hertfordshire, UK

  4. 4

    University of Cambridge, Department of Psychiatry, Cambridge, UK

*Dan J Stein, Department of Psychiatry and Mental Health, University of Cape Town, Education Centre, Valkenberg Hospital, Private Bage X1, Observatory, Cape Town, 7925, South Africa. dan.stein@uct.ac.za.

Publication History

  1. Publication Status: New
  2. Published Online: 8 NOV 2013

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References

References to studies included in this review

  1. References to studies included in this review
  2. References to studies excluded from this review
  3. References to ongoing studies
  4. Additional references
Christenson 1991a {published data only}
Christenson 1994 {unpublished data only}
  • Christenson GA, Crow SJ, Mackenzie TB, Crosby RD, Mitchell JE. A placebo controlled double-blind study of naltrexone for trichotillomania [abstract NR597]. American Psychiatric Assocation Annual Meeting. Philadelphia: APA, 1994:212.
Dougherty 2006 {published data only}
  • Dougherty DD, Loh R, Jenike MA, Keuthen NJ. Single modality versus dual modality treatment for trichotillomania: sertraline, behavioral therapy, or both?. Journal of Clinical Psychiatry 2006;67(7):1086-92.
Grant 2009 {published data only}
  • Grant JE, Odlaug BL, Kim SW. N-acetylcysteine, a glutamate modulator, in the treatment of trichotillomania: a double-blind, placebo-controlled study. Archives of General Psychiatry 2009;66(7):756-63.
Ninan 2000 {published data only}
  • Ninan PT, Rothbaum BO, Marsteller FA, Knight BT, Eccard MA. A placebo-controlled trial of cognitive-behavioral therapy and clomipramine in trichotillomania. Journal of Clinical Psychiatry 2000;61(1):47-50.
Streichenwein 1995 {published data only}
  • Streichenwein SM, Thornby JI. A long-term, double-blind, placebo-controlled crossover trial of the efficacy of fluoxetine for trichotillomania. American Journal of Psychiatry 1995;152(8):1192-6.
Swedo 1989 {published data only}
Van Ameringen 2010 {published data only}
  • Van Ameringen M, Mancini C, Patterson B, Bennett M, Oakman J. A randomized, double-blind, placebo-controlled trial of olanzapine in the treatment of trichotillomania. Journal of Clinical Psychiatry 2010;71(10):1336-43.

References to studies excluded from this review

  1. References to studies included in this review
  2. References to studies excluded from this review
  3. References to ongoing studies
  4. Additional references
Bloch 2013 {published data only}
  • Bloch M, Panza K, Grant JE, Leckman J, Pittenger C. N-acetylcysteine in the treatment of pediatric trichotillomania: a randomized, double-blind, placebo-controlled trial [abstract]. Neuropsychopharmacology [abstracts of the 51st Annual Meeting of the American College of Neuropsychopharmacology, ACNP; 2012 February 2-6; Hollywood, FL, United States] 2012;38:S270.
  • Bloch MH, Panza KE, Grant JE, Pittenger C, Leckman JF. N-acetylcysteine in the treatment of pediatric trichotillomania: a randomized, double-blind, placebo-controlled add-on trial. Journal of the American Academy of Child and Adolescent Psychiatry March 2013;52(3):231-40.
Chamberlain 2010 {published data only}
Riley 1993 {published data only}
Van Minnen 2003 {published data only}
  • Van Minnen A, Hoogduin KAL, Keijsers GPJ, Hellenbrand I, Hendriks GJ. Treatment of trichotillomania with behavioral therapy or fluoxetine. Archives of General Psychiatry 2003;60:517-22.

References to ongoing studies

  1. References to studies included in this review
  2. References to studies excluded from this review
  3. References to ongoing studies
  4. Additional references
Grant 2012 {published data only}
  • Grant JE. A double-blind, placebo-controlled study of naltrexone in trichotillomania. ClinicalTrials.gov/ct2/show/NCT00775229 (accessed 6 August 2013).
Grant 2013 {published data only}
  • Grant JE. A double-blind, placebo-controlled study of inositol in trichotillomania. ClinicalTrials.gov/ct2/show/NCT01875445 (accessed 18 August 2013).

Additional references

  1. References to studies included in this review
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  3. References to ongoing studies
  4. Additional references
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Chamberlain 2008
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Christenson 1998
  • Christenson GA, Crow SJ, Mitchell JE, Mackenzie TB, Crosby RD. Fluvoxamine in the treatment of trichotillomania. CNS Spectrums 1998;3(9):64-71.
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