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Laparoscopy for the management of acute lower abdominal pain in women of childbearing age

  1. Hernando G Gaitán1,*,
  2. Ludovic Reveiz2,
  3. Cindy Farquhar3,
  4. Vanessa M Elias4

Editorial Group: Cochrane Gynaecology and Fertility Group

Published Online: 22 MAY 2014

Assessed as up-to-date: 22 OCT 2013

DOI: 10.1002/14651858.CD007683.pub3


How to Cite

Gaitán HG, Reveiz L, Farquhar C, Elias VM. Laparoscopy for the management of acute lower abdominal pain in women of childbearing age. Cochrane Database of Systematic Reviews 2014, Issue 5. Art. No.: CD007683. DOI: 10.1002/14651858.CD007683.pub3.

Author Information

  1. 1

    National University of Colombia, Department of Obstetrics & Gynecology and Clinical Research Institute, Faculty of Medicine, Bogota, Colombia

  2. 2

    Free time independent Cochrane reviewer, Potomac, USA

  3. 3

    University of Auckland, Department of Obstetrics and Gynaecology, Auckland, New Zealand

  4. 4

    Ecole des Hautes Etudes en Santé Publique, Paris, France

*Hernando G Gaitán, Department of Obstetrics & Gynecology and Clinical Research Institute, Faculty of Medicine, National University of Colombia, Carrera 30 No. 45-03, Bogota, Colombia. hggaitand@unal.edu.co. hernando.gaitan@gmail.com.

Publication History

  1. Publication Status: New search for studies and content updated (no change to conclusions)
  2. Published Online: 22 MAY 2014

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References

References to studies included in this review

  1. References to studies included in this review
  2. References to studies excluded from this review
  3. References to ongoing studies
  4. Additional references
Al-Mulhim 2002 {published data only}
  • Al-Mulhim AS, Al-Mulhim FM, Al-Suwaiygh AA, Al-Masaud NA. Laparoscopic versus open appendectomy in females with a clinical diagnosis of appendicitis. Saudi Medical Journal 2002;23(11):1339-42. [PUBMED: 12506292]
Bruwer 2003 {published data only}
  • Bruwer F, Coetzer M, Warren BL. Laparoscopic versus open surgical exploration in premenopausal women with suspected acute appendicitis. South African Journal of Surgery. Suid-Afrikaanse Tydskrif vir Chirurgie 2003;41(4):82-5. [PUBMED: 14768141]
Champault 1993 {published data only}
  • Champault G, Rizk N, Lauroy J, Olivares P, Belhassen A, Boutelier P. Right iliac fossa pain in women. Conventional diagnostic approach versus primary laparoscopy. A controlled study (65 cases) [Douleurs iliaques droites de la femme. Approche diagnostique conventionnelle versus laparoscopie pre,iere. Etude controlee (65 cas)]. Annales de Chirugie 1993;47(4):316-9.
Decadt 1999 {published data only}
Gaitan 2002 {published data only}
  • Gaitán H, Angel E, Sánchez J, Gómez I, Sánchez L, Agudelo C. Laparoscopic diagnosis of acute lower abdominal pain in women of reproductive age. International Journal of Gynaecology and Obstetrics 2002;76(2):149-58.
Jadallah 1994 {published data only}
  • Jadallah FA, Abdul-Ghani AA, Tibblin S. Diagnostic laparoscopy reduces unnecessary appendicectomy in fertile women. The European Journal of Surgery = Acta Chirurgica 1994;160(1):41-5. [PUBMED: 8186313]
Laine 1997 {published data only}
Larsson 2001 {published data only}
  • Larsson PG, Henriksson G, Olsson M, Boris J, Ströberg P, Tronstad SE, et al. Laparoscopy reduces unnecessary appendicectomies and improves diagnosis in fertile women. A randomized study. Surgical Endoscopy 2001;15(2):200-2.
Morino 2006 {published data only}
  • Morino M, Pellegrino L, Castagna E, Farinella E, Mao P. Acute nonspecific abdominal pain: a randomized, controlled trial comparing early laparoscopy versus clinical observation. Annals of Surgery 2006;244(6):881-6.
Navarra 2002 {published data only}
  • Navarra G, Ascanelli S Turini A, Carcoforo P, Tonini G, Pozza E. Laparoscopic appendectomy versus open appendectomy in suspected acute appendicitis in female patients [Appendicectomia laparoscopica versus appendicectomia aperta nel sospetto di appendicite acuta in pazienti di sesso femminile]. Annali Italiani di Chirurgia 2002;73:59-64.
Olsen 1993 {published data only}
van Dalen 2003 {published data only}
  • Van Dalen R, Bagshaw PF, Dobbs BR, Robertson GM, Lynch AC, Frizelle FA. The utility of laparoscopy in the diagnosis of acute appendicitis in women of reproductive age. Surgical Endoscopy 2003;17(8):1311-3.

References to studies excluded from this review

  1. References to studies included in this review
  2. References to studies excluded from this review
  3. References to ongoing studies
  4. Additional references
Attwood 1992 {published data only}
  • Attwood SE, Hill AD, Murphy PG, Thornton J, Stephens RB. A prospective randomized trial of laparoscopic versus open appendectomy. Surgery 1992;112(3):497-501. [PUBMED: 1387739]
Bauwens 1998 {published data only}
  • Bauwens K, Schwenk W, Bohm B, Hasart O, Neudecker J, Muller JM. Recovery and duration of work disability after laparoscopic and conventional appendectomy. A prospective randomized study [Rekonvaleszenz und Arbeitsunfahigkeitsdauer nach laparoskopischer und konventioneller Appendektomie. Eine prospektiv-randomisierte Studie.]. Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen 1998;69(5):541-5. [PUBMED: 9653559]
Cho 2011 {published data only}
Clarke 2011 {published data only}
  • Clarke T, Katkhouda N, Mason RJ, Cheng BC, Olasky J, Sohn HJ, et al. Laparoscopic versus open appendectomy for the obese patient: a subset analysis from a prospective, randomized, double-blind study. Surgical Endoscopy 2011;25(4):1276-80.
Cox 1996 {published data only}
  • Cox MR, McCall JL, Toouli J, Padbury RT, Wilson TG, Wattchow DA, et al. Prospective randomized comparison of open versus laparoscopic appendectomy in men. World Journal of Surgery 1996;20(3):263-6. [PUBMED: 8661828]
de Wilde 1991 {published data only}
  • de Wilde RL. Goodbye to late bowel obstruction after appendicectomy. Lancet 1991; Vol. 338, issue 8773:1012. [PUBMED: 1681313]
Eichen 1994 {published data only}
  • Eichen R, Heuser H, Nitschke B. Laparoscopic or conventional appendectomy: a prospective study. Langenbecks Archiv fur Chirurgie. Supplement. Kongressband 1994;111:223-5.
Frazee 1994 {published data only}
  • Frazee RC, Roberts JW, Symmonds RE, Snyder SK, Hendricks JC, Smith RW, et al. A prospective randomized trial comparing open versus laparoscopic appendectomy. Annals of Surgery 1994;219(6):725-8; discussion 728-31. [PUBMED: 8203983]
Goudar 2011 {published data only}
  • Goudar BV, Telkar S, Lamani YP, Shirbir SH, Shailesh ME. Laparoscopic versus open appendectomy: a comparison of primary outcome studies from Southern India. Journal of Clinical and Diagnostic Research 2011;5(8):1606-9.
Hansen 1996 {published data only}
  • Hansen JB, Smithers BM, Schache D, Wall DR, Miller BJ, Menzies BL. Laparoscopic versus open appendectomy: prospective randomized trial. World Journal of Surgery 1996;20(1):17-20; discussion 21. [PUBMED: 8588406]
Hart 1996 {published data only}
  • Hart R, Rajgopal C, Plewes A, Sweeney J, Davies W, Gray D, et al. Laparoscopic versus open appendectomy: a prospective randomized trial of 81 patients. Canadian Journal of Surgery. Journal Canadien de Chirurgie 1996;39(6):457-62. [PUBMED: 8956810]
Hebebrand 1994 {published data only}
  • Hebebrand D, Troidl H, Spangenberger W, Neugebauer E, Schwalm T, Gunther MW. Laparoscopic or classical appendectomy? A prospective randomized study [Laparoskopische oder klassische Appendektomie? Eine prospektiv randomisierte Studie.]. Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen 1994;65(2):112-20. [PUBMED: 8162812]
Heikkinen 1998 {published data only}
Hellberg 1999 {published data only}
Helmy 2001 {published data only}
  • Helmy MA. A comparative study between laparoscopic versus open appendicectomy in men. Journal of the Egyptian Society of Parasitology 2001;31(2):555-62. [PUBMED: 11478454]
Henle 1996 {published data only}
  • Henle KP, Beller S, Rechner J, Zerz A, Szinicz G, Klingler A. Laparoscopic versus conventional appendectomy: a prospective randomized study [Laparoskopische versus konventionelle Appendektomie: eine prospektive, randomisierte Studie.]. Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen 1996;67(5):526-30; discussion 522. [PUBMED: 8777883]
Huang 2001 {published data only}
  • Huang MT, Wei PL, Wu CC, Lai IR, Chen RJ, Lee WJ. Needlescopic, laparoscopic, and open appendectomy: a comparative study. Surgical Laparoscopy, Endoscopy & Percutaneous Techniques 2001;11(5):306-12. [PUBMED: 11668227]
Ignacio 2004 {published data only}
  • Ignacio RC, Burke R, Spencer D, Bissell C, Dorsainvil C, Lucha PA. Laparoscopic versus open appendectomy: what is the real difference? Results of a prospective randomized double-blinded trial. Surgical Endoscopy 2004;18(2):334-7. [PUBMED: 14691696]
Kald 1999 {published data only}
  • Kald A, Kullman E, Anderberg B, Wiren M, Carlsson P, Ringqvist I, et al. Cost-minimisation analysis of laparoscopic and open appendicectomy. The European Journal of Surgery = Acta Chirurgica 1999;165(6):579-82. [PUBMED: 10433143]
Kaplan 2009 {published data only}
  • Kaplan M, Salman B, Yilmaz TU, Oguz M. A quality of life comparison of laparoscopic and open approaches in acute appendicitis: a randomised prospective study. Acta Chirurgica Belgica 2009;109(3):356-63.
Karadayi 2003 {published data only}
  • Karadayi K, Turan M, Canbay E, Topcu O, Sen M. Laparoscopic versus open appendectomy: analysis of systemic acute-phase responses in a prospective randomized study. Chirurgische Gastroenterologie 2003;19:396-400.
Kargar 2011 {published data only}
  • Kargar S, Mirshamsi MH, Zare M, Arefanian S, Shadman Yazdi E, Aref A. Laparoscopic versus open appendectomy; which method to choose? A prospective randomized comparison. Acta Med Iran 2011;49(6):352-6.
Kazemier 1997 {published data only}
Khalil 2013 {published data only}
Koluh 2010 {published data only}
  • Koluh A, Delibegovic S, Hasukic S, Valjan V, Latic F. Laparoscopic appendectomy in the treatment of acute appendicitis. Medicinski Archive 2010;64(3):147-50.
Kouhia 2010 {published data only}
Kum 1993 {published data only}
Lavonius 2001 {published data only}
  • Lavonius MI, Liesjarvi S, Ovaska J, Pajulo O, Ristkari S, Alanen M. Laparoscopic versus open appendectomy in children: a prospective randomised study. European Journal of Pediatric Surgery = Zeitschrift fur Kinderchirurgie 2001;11(4):235-8. [PUBMED: 11558012]
Lejus 1996 {published data only}
  • Lejus C, Delile L, Plattner V, Baron M, Guillou S, Heloury Y, et al. Randomized, single-blinded trial of laparoscopic versus open appendectomy in children: effects on postoperative analgesia. Anesthesiology 1996;84(4):801-6. [PUBMED: 8638833]
Lintula 2004 {published data only}
  • Lintula H, Kokki H, Vanamo K, Valtonen H, Mattila M, Eskelinen M. The costs and effects of laparoscopic appendectomy in children. Archives of Pediatrics & Adolescent Medicine 2004;158(1):34-7. [PUBMED: 14706955]
Little 2002 {published data only}
  • Little DC, Custer MD, May BH, Blalock SE, Cooney DR. Laparoscopic appendectomy: an unnecessary and expensive procedure in children?. Journal of Pediatric Surgery 2002;37(3):310-7. [PUBMED: 11877640]
Long 2001 {published data only}
  • Long KH, Bannon MP, Zietlow SP, Helgeson ER, Harmsen WS, Smith CD, et al. A prospective randomized comparison of laparoscopic appendectomy with open appendectomy: clinical and economic analyses. Surgery 2001;129(4):390-400. [PUBMED: 11283528]
Macarulla 1997a {published data only}
  • Macarulla E, Vallet J, Abad JM, Hussein H, Fernandez E, Nieto B. Laparoscopic versus open appendectomy: a prospective randomized trial. Surgical Laparoscopy & Endoscopy 1997;7(4):335-9. [PUBMED: 9282768]
Martin 1995 {published data only}
  • Martin LC, Puente I, Sosa JL, Bassin A, Breslaw R, McKenney MG, et al. Open versus laparoscopic appendectomy. A prospective randomized comparison. Annals of Surgery 1995;222(3):256-61; discussion 261-2. [PUBMED: 7677456]
McAnena 1992 {published data only}
Meynaud-Kraemer 1999 {published data only}
  • Meynaud-Kraemer L, Colin C, Vergnon P, Barth X. Wound infection in open versus laparoscopic appendectomy. A meta-analysis. International Journal of Technology Assessment in Health Care 1999;15(2):380-91. [PUBMED: 10507196]
Minne 1997 {published data only}
  • Minne L, Varner D, Burnell A, Ratzer E, Clark J, Haun W. Laparoscopic vs open appendectomy. Prospective randomized study of outcomes. Archives of Surgery 1997;132(7):708-11; discussion 712. [PUBMED: 9230853]
Moirangthem 2008 {published data only}
  • Moirangthem GS, Arunkumar Ch, Marak AB, Lokendra K, Singh LD. A comparative study between laparoscopic versus open appendicectomy. Journal of Medical Society 2008;22(2):58-62.
Mutter 1996 {published data only}
  • Mutter D, Vix M, Bui A, Evrard S, Tassetti V, Breton JF, et al. Laparoscopy not recommended for routine appendectomy in men: results of a prospective randomized study. Surgery 1996;120(1):71-4. [PUBMED: 8693426]
Nordentoft 2000 {published data only}
  • Nordentoft T, Bringstrup FA, Bremmelgaard A, Stage JG. Effect of laparoscopy on bacteremia in acute appendicitis: a randomized controlled study. Surgical Laparoscopy, Endoscopy & Percutaneous Techniques 2000;10(5):302-4. [PUBMED: 11083213]
Ortega 1995 {published data only}
  • Ortega AE, Hunter JG, Peters JH, Swanstrom LL, Schirmer B. A prospective, randomized comparison of laparoscopic appendectomy with open appendectomy. Laparoscopic Appendectomy Study Group. American Journal of Surgery 1995;169(2):208-12; discussion 212-3. [PUBMED: 7840381]
Ozmen 1999 {published data only}
  • Ozmen MM, Zulfikaroglu B, Tanik A, Kale IT. Laparoscopic versus open appendectomy: prospective randomized trial. Surgical Laparoscopy, Endoscopy & Percutaneous Techniques 1999;9(3):187-9. [PUBMED: 10803997]
Pedersen 2001 {published data only}
Perner 1999 {published data only}
  • Perner A, Bugge K, Lyng KM, Schulze S, Kristensen PA, Bendtsen A. Changes in plasma potassium concentration during carbon dioxide pneumoperitoneum. British Journal of Anaesthesia 1999;82(1):137-9. [PUBMED: 10325852]
Reiertsen 1997 {published data only}
  • Reiertsen O, Larsen S, Trondsen E, Edwin B, Faerden AE, Rosseland AR. Randomized controlled trial with sequential design of laparoscopic versus conventional appendicectomy. The British Journal of Surgery 1997;84(6):842-7. [PUBMED: 9189105]
Schietroma 2007 {published data only}
  • Schietroma M, Cappelli S, Carlei F, Pescosolido A, Lygidakis NJ, Amicucci G. "Acute abdomen": early laparoscopy or active laparotomic-laparoscopic observation?. Hepatogastroenterology 2007;54:1137-41.
Schippers 1994 {published data only}
  • Schippers E, Pier A, May P, Schumpelick V. Laparoscopic vs open appendectomy—a comparison of postoperative pain and respiratory function [abstract]. Surgical Endoscopy 1994;8:561.
Settmacher 1995 {published data only}
  • Settmacher U, Manger T, Liebenthal C, Neuhaus K, Volk HD. Immunological modifications after open and laparoscopic surgery. Minimal Invasive Chirurgie 1995;4:95-102.
Sezeur 1997 {published data only}
  • Sezeur A, Bure-Rossier AM, Rio D, Savigny B, Tricot C, Martel P, et al. Does laparoscopy increase the bacteriological risk of appendectomy? Results of a randomized prospective study [La coelioscopie augmente-t-elle le risque bacteriologique de l'appendicectomie? Resultats d'une etude prospective randomisee.]. Annales de Chirurgie 1997;51(3):243-7. [PUBMED: 9297886]
Shirazi 2010 {published data only}
  • Shirazi B, Ali N, Shamim MS. Laparoscopic versus open appendectomy: a comparative study. Journal of Pakistan Medical Association 2010;60(11):901-4.
Stare 1998 {published data only}
  • Stare R, Kocman I, Povsic Cevra Z. Results of a prospective randomised study of laparoscopic appendectomy in community hospital [abstract]. Surgical Endoscopy 1998;12:573.
St Peter 2011 {published data only}
  • St Peter SD, Adibe OO, Juang D, Sharp SW, Garey CL, Laituri CA, et al. Single incision versus standard 3-port laparoscopic appendectomy: a prospective randomized trial. Annals of Surgery 2011;254(4):586-90.
Tate 1993 {published data only}
Tzovaras 2010 {published data only}
  • Tzovaras G, Baloyiannis I, Kouritas V, Symeonidis D, Spyridakis M, Poultsidi A, et al. Laparoscopic versus open appendectomy in men: a prospective randomized trial. Surgical Endoscopy 2010;24(12):2987-92.
Vallribera 2003 {published data only}
  • Vallribera Valls F, Sala Pedros J, Aguilar Teixedor F, Espin Bassany E. Influence of laparoscopic surgery on perception of quality of life after appendectomy [Influencia de la cirugia laparoscopica en la percepcion de la claidad de vida tras apendicectomia]. Cirugia Espanola 2003;73:88-94.
Wei 2010 {published data only}
Williams 1996 {published data only}
Witten 1998 {published data only}
  • Birth M, Witten I, Gadzepko E, Weiser HF. Laparoscopic vs open appendectomy for acute appendicitis: a prospective randomized trial [abstract]. The British Journal of Surgery 1998;85 Suppl 2:39.
Yeung 1997 {published data only}
  • Yeung CK, Yip KF, Lee KH, Lau WY. The role of minimally invasive surgery in the management of acute appendicitis in children: a prospective randomized trial of laparoscopic vs conventional appendectomy [abstract]. Asian Journal of Surgery 1997;20 Suppl:55.
Zaninotto 1995 {published data only}
  • Zaninotto G, Rossi M, Anselmino M, Costantini M, Pianalto S, Baldan N, et al. Laparoscopic versus conventional surgery for suspected appendicitis in women. Surgical Endoscopy 1995;9(3):337-40.
Zhang 1998 {published data only}
  • Zhang WF, Xu CX, Liu YH, Huang GJ. A randomized control study on the appendectomy of 103 cases with laparoscope or mini-incision. Modern Journal of Physicians 1998;3:8-9.

References to ongoing studies

  1. References to studies included in this review
  2. References to studies excluded from this review
  3. References to ongoing studies
  4. Additional references
ISRCTN42332281 {published data only}
  • Sant'Orsola-Malpighi University Hospital Bologna (sponsor). Multicentre randomised, double-blind, controlled trial of laparoscopic versus open surgery for suspected appendicitis in adults. ISRCTN identifier: ISRCTN42332281 2005; Vol. http://isrctn.org/ISRCTN42332281.

Additional references

  1. References to studies included in this review
  2. References to studies excluded from this review
  3. References to ongoing studies
  4. Additional references
Althoubaity 2006
  • Althoubaity FK. Suspected acute appendicitis in female patients: trends in diagnosis in emergency department in a university hospital in Western Region of Saudi Arabia. Saudi Medical Journal 2006;27:1667-73.
Bennett 2007
  • Bennett J, Boddy A, Rhodes M. Choice of approach for appendicectomy: a meta-analysis of open versus laparoscopic appendicectomy. Surgical Laparoscopy, Endoscopy & Percutaneous Techniques 2007;17(4):245-55. [PUBMED: 17710043]
Beyan 2003
  • Bevan CD, Ridgway GL, Rothermel CD. Efficacy and safety of azithromycin as monotherapy or combined with metronidazole compared with two standard multidrug regimens for the treatment of acute pelvic inflammatory disease. The Journal of International Medical Research 2003;31(1):45-54.
Bijnen 2003
Borgstein 1997
  • Borgstein PJ, Gordijn RV, Eijsbouts QA, Cuesta MA. Acute appendicitis—a clear-cut case in men, a guessing game in young women. A prospective study on the role of laparoscopy. Surgical Endoscopy 1997;11(9):923-7.
CDC 2003 [Computer program]
  • Centers for Disease Control and Prevention. National Hospital Ambulatory Medical Care Survey: 2003 emergency department summary. http://www.cdc.gov.ezproxy.auckland.ac.nz/nchs/data/ad/ad358.pdf (accessed 7 July 2013), 2003.
Flum 2002
Gaitan 2011
  • Gaitán HG, Reveiz L, Farquhar C. Laparoscopy for the management of acute lower abdominal pain in women of childbearing age. Cochrane Database of Systematic Reviews 2011, (1):CD007683.
Golash 2005
Higgins 2011
  • Higgins JPT, Green S (editors). Cochrane Handbook for Systematic Reviews of Interventions Version 5.1.0 [updated March 2011]. The Cochrane Collaboration, 2011. Available from www.cochrane-handbook.org.
Irvin 1989
Kapischke 2006
Koch 2002
  • Koch A, Marusch F, Schmidt U, Gastinger I, Lippert H. Appendicitis in the last decade of the 20th century—analysis of two prospective multicenter clinical observational studies. Zentralblatt fur Chirurgie 2002;127(4):290-6.
Li 2010
  • Li X, Zhang J, Sang L, Zhang W, Chu Z, Li X, Liu Y. Laparoscopic versus conventional appendectomy—a meta-analysis of randomized controlled trials. BMC Gastroenterology 2010;10:129.
Maggio 2008
  • Maggio AQ, Reece-Smith AM, Tang TY, Sadat U, Walsh SR. Early laparoscopy versus active observation in acute abdominal pain: systematic review and meta-analysis. International Journal of Surgery (London, England) 2008;6(5):400-3. [PUBMED: 18760983]
Moberg 1998
Navez 1995
Ou 2000
  • Ou CS, Rowbotham R. Laparoscopic diagnosis and treatment of nontraumatic acute abdominal pain in women. Journal of Laparoendoscopic & Advanced Surgical Techniques. Part A 2000;10(1):41-5.
Poulin 2000
Roper 1988
Sala 2007
  • Sala E, Watson CJ, Beadsmoore C, Groot-Wassink T, Fanshawe TR, Smith JC, et al. A randomized, controlled trial of routine early abdominal computed tomography in patients presenting with non-specific acute abdominal pain. Clinical Radiology 2007;62(10):961-9.
Salky 1998
Sanders 2006
Sauerland 2010
  • Sauerland S, Jaschinski T, Neugebauer EAM. Laparoscopic versus open surgery for suspected appendicitis. Cochrane Database of Systematic Reviews 2010, (10):CD001546.
Sellors 1991
  • Sellors J, Mahony J, Goldsmith C, Rath D, Mander R, Hunter B, et al. The accuracy of clinical findings and laparoscopy in pelvic inflammatory disease. American Journal of Obstetrics and Gynecology 1991;164(1):113-20.
Spirtos 1987
  • Spirtos NM,   Eisenkop SM, Spirtos TW, Poliakin  RI, Hibbard LT. Laparoscopy. A diagnosis aid in cases of suspected appendicitis. Its use in women of reproductive age. American Journal of Obstetrics and Gynecology 1987;156(1):90-4.
Strömberg 2007
Tzovaras 2007
  • Tzovaras G, Liakou P, Baloyiannis I, Spyridakis M, Mantzos F, Tepetes K, et al. Laparoscopic appendectomy: differences between male and female patients with suspected acute appendicitis. World Journal of Surgery 2007;31(2):409-13.
Whitworth 1988
  • Whitworth CM, Whitworth PW, Sanfillipo J, Polk HC. Value of diagnostic laparoscopy in young women with possible appendicitis. Surgery, Gynecology & Obstetrics 1988;167(3):187-90.