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Intervention Review

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Beta-blockers for preventing stroke recurrence

  1. Luiz Gustavo De Lima1,
  2. Bernardo GO Soares1,
  3. Humberto Saconato2,
  4. Álvaro N Atallah3,
  5. Edina MK da Silva4,*

Editorial Group: Cochrane Stroke Group

Published Online: 31 MAY 2013

Assessed as up-to-date: 3 NOV 2011

DOI: 10.1002/14651858.CD007890.pub2


How to Cite

De Lima LG, Soares BGO, Saconato H, Atallah ÁN, da Silva EMK. Beta-blockers for preventing stroke recurrence. Cochrane Database of Systematic Reviews 2013, Issue 5. Art. No.: CD007890. DOI: 10.1002/14651858.CD007890.pub2.

Author Information

  1. 1

    Universidade Federal de São Paulo, Brazilian Cochrane Centre, São Paulo, São Paulo, Brazil

  2. 2

    Santa Casa de Campo Mourão, Department of Medicine, Campo Mourão, Campo Mourão, Brazil

  3. 3

    Centro de Estudos de Medicina Baseada em Evidências e Avaliação Tecnológica em Saúde, Brazilian Cochrane Centre, São Paulo, São Paulo, Brazil

  4. 4

    Universidade Federal de São Paulo, Emergency Medicine and Evidence Based Medicine, São Paulo, São Paulo, Brazil

*Edina MK da Silva, Emergency Medicine and Evidence Based Medicine, Universidade Federal de São Paulo, Rua Pedro de Toledo 598, São Paulo, São Paulo, 04039-001, Brazil. edinaksilva@terra.com.br.

Publication History

  1. Publication Status: New
  2. Published Online: 31 MAY 2013

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This is not the most recent version of the article. View current version (15 OCT 2014)

References

References to studies included in this review

  1. References to studies included in this review
  2. References to studies excluded from this review
  3. Additional references
DUTCH TIA TRIAL 1993 {published data only}
Eriksson 1995 {published data only}

References to studies excluded from this review

  1. References to studies included in this review
  2. References to studies excluded from this review
  3. Additional references
Azuma 1997 {published data only}
  • Azuma T, Matsubara T, Nagai Y, Funauchi M, Fujimoto T, Saito T, et al. Effects of antihypertensive agents on circadian blood pressure in hypertensive patients with previous brain infarction. Journal of Human Hypertension 1997;11:637-40.
Black 2003 {published data only}
  • Black HR, Elliott WJ, Grandits G, Grambsch P, Lucente T, White WB, et al. Principal results of the Controlled ONset Verapamil INvestigation of Cardiovascular End points (CONVINCE) trial. JAMA 2003;289:2073-82.
Coope 1986 {published data only}
Dahlöf 1991 {published data only}
Dahlöf 2002 {published data only}
  • Dahlöf B, Devereux RB, Kjeldsen SE, Julius S, Beevers G, de Faire U, et al. Cardiovascular morbidity and mortality in the Losartan Intervention For Endpoint reduction in hypertension study (LIFE): a randomized trial against atenolol. Lancet 2002;359:995-1003.
Dahlöf 2005 {published data only}
  • Dahlöf B, Sever PS, Poulter NR, Wedel H, Beevers DG, Caulfield M, et al. Prevention of cardiovascular events with an antihypertensive regimen of amlodipine adding perindopril as required versus atenolol adding bendroflumethiazide as required, in the Anglo-Scandinavian Cardiac Outcomes Trial-Blood Pressure Lowering Arm (ASCOT-BPLA): a multicentre randomized controlled trial. Lancet 2005;366:895-906.
Hansson 1999a {published data only}
  • Hansson L, Lindholm LH, Niskanen L, Lanke J, Hedner T, Niklason A, et al. Effect of angiotensin-converting-enzyme inhibition compared with conventional therapy on cardiovascular morbidity and mortality in hypertension: the Captopril Prevention Project (CAPPP) randomized trial. Lancet 1999;353:611-6.
Hansson 1999b {published data only}
  • Hansson L, Lindholm LH, Ekborn T, Dahlöf B, Lanke J, Schersten B, et al. Randomized trial of old and new antihypertensive drugs in elderly patients: cardiovascular mortality and morbidity: the Swedish Trial in Old Patients with Hypertension-2 study. Lancet 1999;354:1751-6.
Hansson 2000 {published data only}
  • Hansson L, Hedner T, Lund-Johansen P, Kjeldsen SE, Lindholm LH, Syvertsen JO, et al. Randomized trial of effects of calcium antagonists compared with diuretics and β-blockers on cardiovascular morbidity and mortality in hypertension: the Nordic Diltiazem (NORDIL) study. Lancet 2000;356:359-65.
Kinnander 1987 {published data only}
MRC 1985 {published data only}
MRC 1992 {published data only}
  • MRC Working Party. Medical Research Council trial of treatment of hypertension in older adults: principal results. BMJ 1982;304:405-12.
SHEP 1991 {published data only}
  • SHEP Cooperative Research Group. Prevention of stroke by antihypertensive drug treatment in older persons with isolated systolic hypertension: final results of the Systolic Hypertension in the Elderly Program (SHEP). JAMA 1991;265:3255-64.
Wilhelmsen 1987 {published data only}
  • Wilhelmsen L, Berglund G, Elmfeldt D, Fitzsimons T, Holzgreve H, Hosie J, et al. Beta-blockers versus diuretics in hypertensive men: main results from the HAPPHY trial. Journal of Hypertension 1987;5:561-72.

Additional references

  1. References to studies included in this review
  2. References to studies excluded from this review
  3. Additional references
BPLTTC 2003
  • Blood Pressure Lowering Treatment Trialists Collaboration. Effects of different blood-pressure-lowering regimens on major cardiovascular events: results of prospectively-designed overviews of randomized trials. Lancet 2003;362:1527-35.
Chalmers 2003
  • Chalmers J, Todd A, Chapman N, Beilin L, Davis S, Donnan G, et al. International Society of Hypertension (ISH): statement on blood pressure lowering and stroke prevention. Journal of Hypertension 2003;21:651-63.
Collins 1990
  • Collins R, Peto R, MacMahon S, Hebert P, Fiebach NH, Eberlein KA, et al. Blood pressure, stroke, and coronary heart disease. Part 2, short-term reductions in blood pressure: overview of randomized drug trials in their epidemiological context. Lancet 1990;335:827-38.
Coull 2004
Dhakam 2006
  • Dhakam Z, McEniery CM, Yasmin C, Cockcroft JR, Brown MJ, Wilkinson IB. Atenolol and eprosartan: differential effects on central blood pressure and aortic pulse wave velocity. American Journal of Hypertension 2006;19(2):214-9.
Gueyffier 1997
  • Gueyffier F, Boissel JP, Boutitie F, Pocock S, Coope J, Cutler J, et al. Effect of antihypertensive treatment in patients having already suffered from stroke. Gathering the evidence. The INDANA (INdividual Data ANalysis of Antihypertensive intervention trials) Project Collaborators. Stroke 1997;12:2557-62.
Hankey 1998
Higgins 2011
  • Higgins JPT, Green S (editors). Cochrane Handbook for Systematic Reviews of Interventions Version 5.1.0 [updated March 2011]. The Cochrane Collaboration. Available from www.cochrane-handbook.org.
Julius 2004
  • Julius S, Kjeldsen SE, Weber M, Brunner HR, Ekman S, Hansson L, et al. Outcomes in hypertensive patients at high cardiovascular risk treated with regimens based on valsartan or amlodipine: the VALUE randomised trial. Lancet 2004;363(9426):2022-31.
Lawes 2008
Lindholm 2005
MacMahon 1990
  • MacMahon S, Peto R, Cutler J, Collins R, Sorlie P, Neaton J, et al. Blood pressure, stroke and coronary heart  disease. Part 1, prolonged differences in blood pressure: prospective observational studies corrected for the regression dilution bias. Lancet 1990;335:765-74.
Messerli 2008
  • Messerli FH, Bangalore S, Julius S. Risk/benefit assessment of beta-blockers and diuretics precludes their use for first-line therapy in hypertension. Circulation 2008;117(20):2706-15.
PROGRESS 2001
  • PROGRESS Collaborative Group. Randomised trial of a perindopril-based blood-pressure lowering regimen among 6,105 individuals with previous stroke or transient ischaemic attack. Lancet 2001;358(9287):1033-41.
RevMan 2011
  • The Nordic Cochrane Centre. The Cochrane Collaboration. Review Manager (RevMan). 5.1. Copenhagen: The Nordic Cochrane Centre. The Cochrane Collaboration, 2011.
Sacco 1997
  • Sacco RL, Benjamin EJ, Broderick JP, Dyken M, Easton JD, Feinberg WM, et al. American Heart Association Prevention Conference: IV: prevention and rehabilitation of stroke: risk factors. Stroke 1997;28:1507-17.
Sacco 2006
  • Sacco RL, Adams R, Albers G, Alberts MJ, Benavente O, Furie K, et al. Guidelines for prevention of stroke in patients with ischemic stroke or transient ischemic attack: a statement for healthcare professionals from the American Heart Association/American Stroke Association Council on Stroke: cosponsored by the Council on Cardiovascular Radiology and Intervention: the American Academy of Neurology affirms the value of this guideline. Stroke 2006;37:577-617.
Shah 2000
  • Shah H, Gondek K. Aspirin plus extended-release dipyridamole or clopidogrel compared with aspirin monotherapy for the prevention of recurrent ischemic stroke: a cost effectiveness analysis. Clinical Therapy 2000;22:363-70.
Smith 2001
  • Smith SC Jr, Blair SN, Bonow RO, Brass LM, Cerqueira MD, Dracup K, et al. American Heart Association/American College of Cardiology guidelines for preventing heart attack and death in patients with atherosclerotic cardiovascular disease: 2001 update: a statement for healthcare professionals from the American Heart Association and the American College of Cardiology. Circulation 2001;104:1577-9.
Strong 2007
Wiysonge 2007