Diagnostic Test Accuracy Protocol

Sentinel node biopsy for diagnosis of pelvic lymph node involvement in early stage cervical cancer

  1. Karen K L Chan1,*,
  2. Christine Ang2,
  3. Andrew Bryant3,
  4. Javier Zamora4,
  5. Raj Naik5

Editorial Group: Cochrane Gynaecological Cancer Group

Published Online: 8 JUL 2009

DOI: 10.1002/14651858.CD007925

Database Title

Additional Information

How to Cite

Chan KKL, Ang C, Bryant A, Zamora J, Naik R. Sentinel node biopsy for diagnosis of pelvic lymph node involvement in early stage cervical cancer (Protocol). Cochrane Database of Systematic Reviews 2009, Issue 3. Art. No.: CD007925. DOI: 10.1002/14651858.CD007925.

Author Information

  1. 1

    Northern Gynaecological Oncology Centre, Gynaecological Oncology, Tyne and Wear, UK

  2. 2

    Leicester Royal Infirmary, Department of Obstetrics and Gynaecology, Leicester, UK

  3. 3

    Newcastle University, Institute of Health and Society, Newcastle upon Tyne, UK

  4. 4

    (b) CIBER Epidemiologia y Salud Publica (CIBERESP), (a) Unidad de Bioestadística, Hospital Ramón y Cajal, Madrid, Spain

  5. 5

    Queen Elizabeth Hospital, Northern Gynaecological Oncology Centre, Gateshead, Tyne and Wear, UK

*Karen K L Chan, Gynaecological Oncology, Northern Gynaecological Oncology Centre, Queen Elizabeth Hospital, Gateshead, Tyne and Wear, NE9 6SX, UK. kklchan@hkucc.hku.hk.

Publication History

  1. Publication Status: Edited (no change to conclusions)
  2. Published Online: 8 JUL 2009

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Abstract

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  2. Abstract

This is the protocol for a review and there is no abstract. The objectives are as follows:

To assess the diagnostic accuracy of sentinel lymph node biopsy in the identification of lymph node involvement in patients with early stage cervical cancer (Stage IA2 to IIA).

We will first explore the impact of major factors for heterogeneity such as tumour size, FIGO stage and timing between application and detection of tracers. Then, we may consider other factors such as previous treatment to the cervix, including conisation and different histological criteria for diagnosis of metastases.

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