Intervention Review

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Intermittent versus daily therapy for treating tuberculosis in children

  1. Anuradha Bose1,*,
  2. Soumik Kalita2,
  3. Winsley Rose3,
  4. Prathap Tharyan4

Editorial Group: Cochrane Infectious Diseases Group

Published Online: 28 JAN 2014

Assessed as up-to-date: 30 MAY 2013

DOI: 10.1002/14651858.CD007953.pub2


How to Cite

Bose A, Kalita S, Rose W, Tharyan P. Intermittent versus daily therapy for treating tuberculosis in children. Cochrane Database of Systematic Reviews 2014, Issue 1. Art. No.: CD007953. DOI: 10.1002/14651858.CD007953.pub2.

Author Information

  1. 1

    Christian Medical College, Department of Community Health, Vellore, India

  2. 2

    GlaxoSmithKline Consumer Healthcare, Family Nutrition, Gurgaon, Haryana, India

  3. 3

    Christian Medical College, Department of Child Health, Vellore, India

  4. 4

    Christian Medical College, South Asian Cochrane Network & Centre, Prof. BV Moses & ICMR Advanced Centre for Research & Training in Evidence Informed Health Care, Vellore, Tamil Nadu, India

*Anuradha Bose, Department of Community Health, Christian Medical College, Vellore, 632002, India. abose@cmcvellore.ac.in.

Publication History

  1. Publication Status: New
  2. Published Online: 28 JAN 2014

SEARCH

[Figure 1]
Figure 1. Flow diagram of the selection process.
[Figure 2]
Figure 2. Methodological quality graph: review authors' judgements about each methodological quality item presented as percentages across all included trials.
[Figure 3]
Figure 3. Methodological quality summary: review authors' judgements about each methodological quality item for each included trial.
[Figure 4]
Figure 4. Forest plot: 1. Intermittent versus daily regimens, Outcome 1.1 Cure (as defined by clinical and radiological improvement): Intention to treat.
[Figure 5]
Figure 5. Forest plot: 1. Intermittent versus daily regimens, Outcome 1.5 Adherence to treatment.
[Analysis 1.1]
Analysis 1.1. Comparison 1 Intermittent versus daily regimens, Outcome 1 Cure (as defined by clinical and radiological improvement): Intention to treat.
[Analysis 1.2]
Analysis 1.2. Comparison 1 Intermittent versus daily regimens, Outcome 2 Cure (as defined by clinical and radiological improvement): Per-protocol (Sensitivity analysis).
[Analysis 1.3]
Analysis 1.3. Comparison 1 Intermittent versus daily regimens, Outcome 3 Death from any cause.
[Analysis 1.4]
Analysis 1.4. Comparison 1 Intermittent versus daily regimens, Outcome 4 Relapse.
[Analysis 1.5]
Analysis 1.5. Comparison 1 Intermittent versus daily regimens, Outcome 5 Adherence to treatment.
[Analysis 1.6]
Analysis 1.6. Comparison 1 Intermittent versus daily regimens, Outcome 6 Treatment-limiting adverse events.