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Oxcarbazepine for neuropathic pain

  1. Muke Zhou1,
  2. Ning Chen1,
  3. Li He1,*,
  4. Mi Yang1,
  5. Cairong Zhu2,
  6. Fengbo Wu3

Editorial Group: Cochrane Neuromuscular Disease Group

Published Online: 28 MAR 2013

Assessed as up-to-date: 30 OCT 2012

DOI: 10.1002/14651858.CD007963.pub2


How to Cite

Zhou M, Chen N, He L, Yang M, Zhu C, Wu F. Oxcarbazepine for neuropathic pain. Cochrane Database of Systematic Reviews 2013, Issue 3. Art. No.: CD007963. DOI: 10.1002/14651858.CD007963.pub2.

Author Information

  1. 1

    West China Hospital, Sichuan University, Department of Neurology, Chengdu, Sichuan, China

  2. 2

    School of Public Health, Sichuan University, Epidemic Disease & Health Statistics Department, Sichuan, Chengdu, China

  3. 3

    West China Hospital, Sichuan University, Department of Pharmacy, Chengdu, Sichuan, China

*Li He, Department of Neurology, West China Hospital, Sichuan University, No. 37, Guo Xue Xiang, Chengdu, Sichuan, 610041, China. heli2003new@126.com.

Publication History

  1. Publication Status: Edited (no change to conclusions)
  2. Published Online: 28 MAR 2013

SEARCH

References

References to studies included in this review

  1. References to studies included in this review
  2. References to studies excluded from this review
  3. References to studies awaiting assessment
  4. References to ongoing studies
  5. Additional references
  6. References to other published versions of this review
Beydoun 2006 {published data only}
  • Beydoun A, Shaibani A, Hopwood M, Wan Y. Oxcarbazepine in painful diabetic neuropathy: results of a dose-ranging study. Acta Neurologica Scandinavica 2006;113(6):395-404. [PUBMED: 16674606]
  • Beydoun A, Wan Y, Hopwood M, Liebel J. Results of a randomized, placebo-controlled trial suggest oxcarbazepine has a therapeutic effect in the treatment of painful diabetic neuropathy. European Journal of Neurology 2004;11 Suppl 2:101.
Dogra 2005 {published data only}
  • Dogra S, Beydoun S, Hopwood M, Mazzola J, Wan Y. Oxcarbazepine in painful diabetic neuropathy: a randomized, placebo-controlled study. Journal of Pain 2004;5(3 Suppl 1):S6.
  • Dogra S, Beydoun S, Mazzola J, Hopwood M, Wan Y. Oxcarbazepine in painful diabetic neuropathy: a randomized, placebo-controlled study. European Journal of Pain 2005;9(5):543-54. [PUBMED: 16139183]
  • Dogra S, Beydoun S, Mazzola J, Hopwood M, Wan Y, Liebel J. Oxcarbazepine provides pain relief in patients with painful diabetic neuropathy: a randomized, placebo-controlled study. European Journal of Neurology 2004;11 Suppl 2:92.
Grosskopf 2006 {published data only}
Novartis 2004 {published and unpublished data}
  • Multicenter, double-blind, randomized, placebo-control, parallel-group study to evaluate the safety and efficacy of oxcarbazepine in patients with neuropathic pain due to radiculopathy. Novartis Clinical Trials Results Database. http://www.novartis.com/innovation/research-development/clinical-trials/index.shtml 2005 (accessed 29 October 2012).
  • Harden RN, Urniasz KL, Hopwood M, Wan Y. Efficacy and safety of oxcarbazepine in patients with neuropathic pain due to radiculopathy: A double-blind, randomized, placebo-controlled study. Neurology 2005;64 Suppl 1:A120-1.

References to studies excluded from this review

  1. References to studies included in this review
  2. References to studies excluded from this review
  3. References to studies awaiting assessment
  4. References to ongoing studies
  5. Additional references
  6. References to other published versions of this review
Beydoun 2002 {published data only}
  • Beydoun A, D'Souza J. Oxcarbazepine versus carbamazepine in patients with new onset trigeminal neuralgia result of double blind comparative trial [abstract no.P06.116]. Neurology 2002;58 Suppl 3:A471.
Beydoun 2007 {published data only}
Gong 2010 {published data only}
  • Gong JJ. A randomised controlled trial of 3 drugs for the treatment of idiopathic trigeminal neuralgia [3种药物治疗原发性三叉神经痛的随机对照试验]. Journal of China Traditional Chinese Medicine Information 2010;2(12):74.
Hu 2010 {published data only}
  • Hu YJ. The comparative efficacy of oxcarbazepine and carbamazepine for trigeminal neuralgia [奥卡西平与卡马西平治疗三次神经痛的疗效对比]. Shandong Medical Journal 2010;50(25):107.
Li 2011 {published data only}
  • Li G, Zha Q, Chen JZ, Cao QH, Peng WJ. Clinical efficacy of oxcarbazepine for primary trigeminal neuralgia [奥卡西平治疗原发性三叉神经痛临床观察]. Zhejiang Journal of Integrated Traditional Chinese and Western Medicine 2011;21(3):167-8.
Lindström 1987 {published data only}
  • Lindström P. The analgesic effect of carbamazepine in trigeminal neuralgia. Pain 1987;28 Suppl 4:S85.
Rémillard 1994 {published data only}
Venancio-Ramirez 2004 {published data only}
  • Venancio-Ramirez L, Hernández-Santos JR, Tenopala-Villegas S, Torres-Huerta JC, Rivera-León G, Canseco-Aguilar C. Comparison of oxcarbazepine and gabapentin at standard dose in treatment of pain for postherpetic neuropathy. Revista Mexicana de Anestesiologia 2004;27(3):129-33.
Zhou 2010 {published data only}
  • Zhou JF. A clinical research on the pharmacological treatment of trigeminal neuralgia [药物治疗三叉神经痛的临床研究]. Medical Information Operations Sciences Fascicule 2010;1:89.

References to studies awaiting assessment

  1. References to studies included in this review
  2. References to studies excluded from this review
  3. References to studies awaiting assessment
  4. References to ongoing studies
  5. Additional references
  6. References to other published versions of this review
Brainer-Lima 2003 {published data only}
  • Brainer-Lima P, Naylor F. Oxcarbazepine for cancer-related neuropathic pain and opiate detoxification. Program and abstracts of the 22nd Annual Meeting of the American Pain Society; March 20-23, 2003; Chicago, Ill. 2003.
Liebel 2001 {published data only}
  • Liebel J. Results of a double-blind trial comparing oxcarbazepine (OXC) vs carbamazepine (CBZ) in newly diagnosed, untreated patients with trigeminal neuralgia. Journal of the Neurological Sciences 2001;187 Suppl 1:S5.

References to ongoing studies

  1. References to studies included in this review
  2. References to studies excluded from this review
  3. References to studies awaiting assessment
  4. References to ongoing studies
  5. Additional references
  6. References to other published versions of this review
NCT01302275 {unpublished data only}
  • NCT01302275. Oxcarbazepine for the treatment of chronic peripheral neuropathic pain (IMIOXC). http://clinicaltrials.gov/ct2/show/NCT01302275 accessed 29 October 2012.

Additional references

  1. References to studies included in this review
  2. References to studies excluded from this review
  3. References to studies awaiting assessment
  4. References to ongoing studies
  5. Additional references
  6. References to other published versions of this review
Attal 2006
Attal 2010
Backonja 2003
Beydoun 2002a
  • Beydoun A, Schmidt D, Souza J. Oxcarbazepine versus carbamazepine in trigeminal neuralgia: a meta-analysis of three double-blind comparative trials. Neurology 2002;58 Suppl 3:A131.
Beydoun 2002b
  • Beydoun A, Schmidt D, D'souza J, on behalf of the oxcarbazepine study group. Meta-analysis of comparative trials of oxcarbazepine versus carbamazepine in trigeminal neuralgia. Poster presented at the 21st American Pain Society Annual Meeting. Baltimore, USA, 14-17 March, 2002.
Bieri 1990
  • Bieri D, Reeve RA, Champion GD, Addicoat L, Ziegler JB. The Faces Pain Scale for the self-assessment of the severity of pain experienced by children: development, initial validation and preliminary investigation for ratio scale properties. Pain 1990;41(2):139-50.
Birse 2012
Callin 2008
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Carpenter 2002
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Carrazana 2003
Corrigan 2012
Criscuolo 2005
Dam 1989
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Davis 2004
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Dickenson 2002
Drug Safety Update 2012
  • Carbamazepine, oxcarbazepine and eslicarbazepine: potential risk of serious skin reactions associated with the HLA-A* 3101 allele. Drug Safety Update 2012; Vol. 6, issue 5:A1. [: http://www.mhra.gov.uk/Safetyinformation/DrugSafetyUpdate/CON214944]
Eisenberg 2007
Finnerup 2007
Foley 2003
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Heliovaara 1987
Higgins 2008
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Higgins 2008b
  • Higgins JPT, Altman DG (editors). Chapter 8: Assessing risk of bias in included studies. In: Higgins JPT, Green S editor(s). Cochrane Handbook for Systematic Reviews of Interventions Version 5.0.1 (updated September 2008). The Cochrane Collaboration, 2008.
Higgins 2009
  • Higgins JPT, Deeks JJ, Altman DG (editors). Chapter 16: Special topics in statistics. In: Higgins JPT, Green S editor(s). Cochrane Handbook for Systematic Reviews of Interventions Version 5.0.2 (updated September 2009). The Cochrane Collaboration, 2009.
Higgins 2011
  • Higgins JPT, Altman DG, Sterne JAC (editors). Chapter 8: Assessing risk of bias in included studies. In: Higgins JPT, Green S, (editors). Cochrane Handbook for Systematic Reviews of Interventions Version 5.1.0 (updated March 2011). The Cochrane Collaboration, 2011. Available from www.cochrane-handbook.org.
Jensen 2001
Jensen 2002
Lindstrom 1987
  • Lindstrom P. The analgesic effect of carbamazepine in trigeminal neuralgia. Pain 1987;30:S85.
Magenta 2005
  • Magenta P, Arghetti S, Di Palma F, Jann S, Sterlicchio M, Bianconi C, et al. Oxcarbazepine is effective and safe in the treatment of neuropathic pain: pooled analysis of seven clinical studies. Neurological Sciences: official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology 2005;26(4):218-26.
Merskey 1994
  • Merskey H, Bogduk N. Classification of Chronic Pain: Descriptions of Chronic Pain Syndromes and Definitions of Pain Terms. 2nd Edition. Seattle: IASP Press, 1994.
Moore 2009
Moore 2011
  • Moore RA, Wiffen PJ, Derry S, McQuay HJ. Gabapentin for chronic neuropathic pain and fibromyalgia in adults.. Cochrane Database of Systematic Reviews 11, Issue 3. [DOI: 10.1002/14651858.CD007938.pub2]
Nasreddine 2007
Schmader 2002
Schünemann 2008
  • Schünemann HJ, Oxman AD, Higgins JPT, et al. Chapter 11: Presenting results and 'Summary of findings' tables. In: Higgins JPT, Green S editor(s). Cochrane Handbook for Systematic Reviews of Interventions Version 5.0.1 (updated September 2008). The Cochrane Collaboration, 2008.
Suzuki 2004
Treede 2008
  • Treede RD, Jensen TS, Campbell JN, Cruccu G, Dostrovsky JO, Griffin JW, et al. Neuropathic pain: redefinition and a grading system for clinical and research purposes. Neurology 2008;70(18):1630-5.
Verma 2005
Ware 1992
Werhagen 2004
  • Werhagen L, Budh CN, Hultling C, Molander C. Neuropathic pain after traumatic spinal cord injury? Relations to gender, spinal level, completeness, and age at the time of injury. Spinal Cord 2004;42(12):665-73.
Wiffen 2010
Wiffen 2011a
Wifffen 2011b
Williamson 2005

References to other published versions of this review

  1. References to studies included in this review
  2. References to studies excluded from this review
  3. References to studies awaiting assessment
  4. References to ongoing studies
  5. Additional references
  6. References to other published versions of this review
Zhou 2009
  • Zhou M, He L, Yang M, Chen N, Guo J, Li Q, Yang X, Yang J, Zhu C. Oxcarbazepine for neuropathic pain. Cochrane Database of Systematic Reviews 2009, Issue 3. [DOI: 10.1002/14651858.CD007963]