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Aspirin with or without an antiemetic for acute migraine headaches in adults

  1. Varo Kirthi,
  2. Sheena Derry*,
  3. R Andrew Moore

Editorial Group: Cochrane Pain, Palliative and Supportive Care Group

Published Online: 30 APR 2013

Assessed as up-to-date: 5 MAR 2013

DOI: 10.1002/14651858.CD008041.pub3


How to Cite

Kirthi V, Derry S, Moore RA. Aspirin with or without an antiemetic for acute migraine headaches in adults. Cochrane Database of Systematic Reviews 2013, Issue 4. Art. No.: CD008041. DOI: 10.1002/14651858.CD008041.pub3.

Author Information

  1. University of Oxford, Pain Research and Nuffield Department of Clinical Neurosciences, Oxford, UK

*Sheena Derry, Pain Research and Nuffield Department of Clinical Neurosciences, University of Oxford, Pain Research Unit, Churchill Hospital, Oxford, OX3 7LE, UK. sheena.derry@ndcn.ox.ac.uk.

Publication History

  1. Publication Status: Stable (no update expected for reasons given in 'What's new')
  2. Published Online: 30 APR 2013

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References

References to studies included in this review

  1. References to studies included in this review
  2. References to studies excluded from this review
  3. Additional references
  4. References to other published versions of this review
Boureau 1994 {published data only}
  • Boureau F, Joubert JM, Lasserre V, Prum B, Delecoeuillerie G. Double-blind comparison of an acetaminophen 400 mg-codeine 25 mg combination versus aspirin 1000 mg and placebo in acute migraine attack. Cephalalgia 1994;14(2):156-61.
Chabriat 1994 {published data only}
  • Chabriat H, Joire JE, Danchot J, Grippon P, Bousser MG. Combined oral lysine acetylsalicylate and metoclopramide in the acute treatment of migraine: a multicentre double-blind placebo-controlled study. Cephalalgia 1994;14(4):297-300.
Diener 2004a {published data only}
Diener 2004b {published data only}
Geraud 2002 {published data only}
  • Geraud G, Compagnon A, Rossi A, COZAM Study Group. Zolmitriptan versus a combination of acetylsalicylic acid and metoclopramide in the acute oral treatment of migraine: a double-blind, randomised, three-attack study. European Neurology 2002;47(2):88-98.
Henry 1995 {published data only}
  • Henry P, Hiesse-Provost O, Dillenschneider A, Ganry H, Insuasty J. Efficacy and tolerance of an effervescent aspirin-metoclopramide combination in the treatment of a migraine attack. Randomized double-blind study using a placebo [Efficacite et tolerance de l'association effervescente aspirine-metoclopramide dans le traitement de la crise de migraine sans aura. Essai randomise en double aveugle contre placebo]. Presse Medicale 1995;24(5):254-8.
Lange 2000 {published data only}
  • Lange R, Schwarz JA, Hohn M. Acetylsalicylic acid effervescent 1000 mg (Aspirin) in acute migraine attacks; a multicentre, randomized, double-blind, single-dose, placebo-controlled parallel group study. Cephalalgia 2000;20(7):663-7.
Le Jeunne 1998 {published data only}
  • Le Jeunne C, Pascual Gómez J, Pradalier A, Titus i Albareda F, Joffroy A, Liaño H, et al. Comparative efficacy and safety of calcium carbasalate plus metoclopramide versus ergotamine tartrate plus caffeine in the treatment of acute migraine attacks. European Neurology 1999;41(1):37-43.
Lipton 2005 {published data only}
MacGregor 2002 {published data only}
Tfelt-Hansen 1995 {published data only}
  • Tfelt-Hansen P, Henry P, Mulder LJ, Scheldewaert RG, Schoenen J, Chazot G. The effectiveness of combined oral lysine acetylsalicylate and metoclopramide compared with oral sumatriptan for migraine. Lancet 1995;346(8980):923-6.
Thomson 1992 {published data only}
  • Thomson CJ, The Oral Sumatriptan and Aspirin plus Metoclopramide Comparative Study Group. A study to compare oral sumatriptan with oral aspirin plus oral metoclopramide in the acute treatment of migraine. European Neurology 1992;32(3):177-84.
Titus 2001 {published data only}
  • Titus F, Escamilla C, Gomes da Costa Palmeira MM, Leira R, Pereira Monteiro JM. A double-blind comparison of lysine acetylsalicylate plus metoclopramide vs ergotamine plus caffeine in migraine: effects on nausea, vomiting and headache symptoms. Clinical Drug Investigation 2001;21(2):87-94.

References to studies excluded from this review

  1. References to studies included in this review
  2. References to studies excluded from this review
  3. Additional references
  4. References to other published versions of this review
Chabriat 1993 {published data only}
  • Chabriat H, Joire JE, Danchot J, Bousser MG. Association of aspirin and metoclopramide in the treatment of migraine attacks. Cephalagia 1993;13(13):96.
Diener 2005 {published data only}
  • Diener HC, Pfaffenrath V, Pageler L, Peil H, Aicher B. The fixed combination of acetylsalicylic acid, paracetamol and caffeine is more effective than single substances and dual combination for the treatment of headache: a multicentre, randomized, double-blind, single-dose, placebo-controlled parallel group study. Cephalalgia 2005;25(10):776-87.
Limmroth 1999 {published data only}
Nebe 1995 {published data only}
  • Nebe J, Heier M, Diener HC. Low-dose ibuprofen in self-medication of mild to moderate headache: a comparison with acetylsalicylic acid and placebo. Cephalalgia 1995;15(6):531-5.
Tfelt-Hansen 1980 {published data only}
Tfelt-Hansen 1984 {published data only}

Additional references

  1. References to studies included in this review
  2. References to studies excluded from this review
  3. Additional references
  4. References to other published versions of this review
Ayzenberg 2012
Bigal 2008
Bloudek 2012
  • Bloudek LM, Stokes M, Buse DC, Wilcox TK, Lipton RB, Goadsby PJ, et al. Cost of healthcare for patients with migraine in five European countries: results from the International Burden of Migraine Study (IBMS). Journal of Headache and Pain 2012;13(5):361-78. [DOI: 10.1007/s10194-012-0460-7]
Buse 2011
Collins 1997
Colman 2004
Cook 1995
Derry 2000
Derry 2012b
  • Derry CJ, Derry S, Moore RA. Sumatriptan (oral route of administration) for acute migraine attacks in adults. Cochrane Database of Systematic Reviews 2012, Issue 2. [DOI: 10.1002/14651858.CD008615.pub2]
Derry 2013a
  • Derry S, Moore RA, McQuay HJ. Paracetamol (acetaminophen) with or without an antiemetic for acute migraine headaches in adults. Cochrane Database of Systematic Reviews 2013, Issue 4. [DOI: 10.1002/14651858.CD008040.pub3]
Derry 2013b
  • Derry S, Rabbie R, Moore RA. Diclofenac with or without an antiemetic for acute migraine headaches in adults. Cochrane Database of Systematic Reviews 2013, Issue 4. [DOI: 10.1002/14651858.CD008783.pub3]
Diamond 2007
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Elbourne 2002
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Gendolla 2008
Haag 2011
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IHS 1988
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Linde 2012
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Moore 2008
  • Moore RA, Barden J, Derry S, McQuay HJ. Managing potential publication bias. In: McQuay HJ, Kalso E, Moore RA editor(s). Systematic Reviews in Pain Research: Methodology Refined. Seattle: IASP Press, 2008:15-24. [ISBN: 978-0-931092-69-5]
Morris 1995
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Salazar-Tortolero 2008
  • Salazar-Tortolero G, Huertas-Campistol A, Vergez-Pinto L, Ramos-Brunet A, Lluch-López J. Metoclopramide as a painkiller for intense migraine headache in emergency departments [Metoclopramida como analgésicoen la cefalea migrañosa intensa en urgencias]. Revista de Neurologia 2008;47(10):506-8.
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References to other published versions of this review

  1. References to studies included in this review
  2. References to studies excluded from this review
  3. Additional references
  4. References to other published versions of this review
Kirthi 2010