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Hyperbaric oxygen therapy for treating acute surgical and traumatic wounds

  1. Anne Eskes1,
  2. Hester Vermeulen2,
  3. Cees Lucas3,
  4. Dirk T Ubbink4,*

Editorial Group: Cochrane Wounds Group

Published Online: 16 DEC 2013

Assessed as up-to-date: 21 AUG 2013

DOI: 10.1002/14651858.CD008059.pub3


How to Cite

Eskes A, Vermeulen H, Lucas C, Ubbink DT. Hyperbaric oxygen therapy for treating acute surgical and traumatic wounds. Cochrane Database of Systematic Reviews 2013, Issue 12. Art. No.: CD008059. DOI: 10.1002/14651858.CD008059.pub3.

Author Information

  1. 1

    Academic Medical Centre, University of Amsterdam & Amsterdam School of Health Professions, Quality Assurance & Process Innovation, Amsterdam, Netherlands

  2. 2

    Academic Medical Centre, University of Amsterdam & Amsterdam School of Health Professions, Department of Quality Assurance & Process Innovation, Amsterdam, Noord-Holland, Netherlands

  3. 3

    Academic Medical Centre, University of Amsterdam, Department of Clinical Epidemiology, Biostatistics and Bioinformatics, Amsterdam, Netherlands

  4. 4

    Academic Medical Centre, University of Amsterdam, Quality Assurance & Process Innovation, and Department of Surgery, Amsterdam, Netherlands

*Dirk T Ubbink, Quality Assurance & Process Innovation, and Department of Surgery, Academic Medical Centre, University of Amsterdam, J1b-215 Academic Medical Centre, Meibergdreef 9, PO Box 22700, Amsterdam, 1100 DE, Netherlands. d.ubbink@amc.uva.nl.

Publication History

  1. Publication Status: New search for studies and content updated (no change to conclusions)
  2. Published Online: 16 DEC 2013

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[Figure 1]
Figure 1. Study flow diagram.
[Figure 2]
Figure 2. Methodological quality graph: review authors' judgements about each methodological quality item presented as percentages across all included studies.
[Figure 3]
Figure 3. Methodological quality summary: review authors' judgements about each methodological quality item for each included study.
[Analysis 1.1]
Analysis 1.1. Comparison 1 HBOT compared with usual care, Outcome 1 Complete survival (defined as at least 95% take) at day 7.
[Analysis 2.1]
Analysis 2.1. Comparison 2 HBOT compared with sham HBOT, Outcome 1 Complete healing.
[Analysis 2.2]
Analysis 2.2. Comparison 2 HBOT compared with sham HBOT, Outcome 2 Time to healing (days).
[Analysis 2.3]
Analysis 2.3. Comparison 2 HBOT compared with sham HBOT, Outcome 3 Adverse effects (additional surgical procedures).
[Analysis 2.4]
Analysis 2.4. Comparison 2 HBOT compared with sham HBOT, Outcome 4 Adverse effects (tissue necrosis).
[Analysis 2.5]
Analysis 2.5. Comparison 2 HBOT compared with sham HBOT, Outcome 5 Amputations.
[Analysis 2.6]
Analysis 2.6. Comparison 2 HBOT compared with sham HBOT, Outcome 6 Length of hospital stay.
[Analysis 3.1]
Analysis 3.1. Comparison 3 HBOT compared with dexamethasone or heparin, Outcome 1 Complete healing HBOT vs dexamethasone.
[Analysis 3.2]
Analysis 3.2. Comparison 3 HBOT compared with dexamethasone or heparin, Outcome 2 Complete healing HBOT vs heparin.