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Hyperbaric oxygen therapy for treating acute surgical and traumatic wounds

  1. Anne Eskes1,
  2. Hester Vermeulen2,
  3. Cees Lucas3,
  4. Dirk T Ubbink4,*

Editorial Group: Cochrane Wounds Group

Published Online: 16 DEC 2013

Assessed as up-to-date: 21 AUG 2013

DOI: 10.1002/14651858.CD008059.pub3


How to Cite

Eskes A, Vermeulen H, Lucas C, Ubbink DT. Hyperbaric oxygen therapy for treating acute surgical and traumatic wounds. Cochrane Database of Systematic Reviews 2013, Issue 12. Art. No.: CD008059. DOI: 10.1002/14651858.CD008059.pub3.

Author Information

  1. 1

    Academic Medical Centre, University of Amsterdam & Amsterdam School of Health Professions, Quality Assurance & Process Innovation, Amsterdam, Netherlands

  2. 2

    Academic Medical Centre, University of Amsterdam & Amsterdam School of Health Professions, Department of Quality Assurance & Process Innovation, Amsterdam, Noord-Holland, Netherlands

  3. 3

    Academic Medical Centre, University of Amsterdam, Department of Clinical Epidemiology, Biostatistics and Bioinformatics, Amsterdam, Netherlands

  4. 4

    Academic Medical Centre, University of Amsterdam, Quality Assurance & Process Innovation, and Department of Surgery, Amsterdam, Netherlands

*Dirk T Ubbink, Quality Assurance & Process Innovation, and Department of Surgery, Academic Medical Centre, University of Amsterdam, J1b-215 Academic Medical Centre, Meibergdreef 9, PO Box 22700, Amsterdam, 1100 DE, Netherlands. d.ubbink@amc.uva.nl.

Publication History

  1. Publication Status: New search for studies and content updated (no change to conclusions)
  2. Published Online: 16 DEC 2013

SEARCH

References

References to studies included in this review

  1. References to studies included in this review
  2. References to studies excluded from this review
  3. References to ongoing studies
  4. Additional references
  5. References to other published versions of this review
Bouachour 1996 {published data only}
  • Bouachour G, Cronier P, Gouello JP, Toulemonde JL, Talha A, Alquier P. Hyperbaric oxygen therapy in the management of crush injuries: a randomized double-blind placebo-controlled clinical trial. Journal of Trauma 1996;41(2):333-9.
Perrins 1967 {published data only}
  • Perrins DJ. Influence of hyperbaric oxygen on the survival of split skin grafts. Lancet 1967;289(7495):868-71.
Vishwanath 2011 {published data only}
  • Vishwanath G. Hyperbaric oxygen therapy in free flap surgery: Is it meaningful?. Medical Journal Armed Forces India 2011;67(3):253-6.
Xie 2007 {published data only}
  • Xie Z-X, Li C-Y. Changes in arterial flow after flap grafting under various tensions. Journal of Clinical Rehabilitative Tissue Engineering Research 2007;11(25):5004-5.

References to studies excluded from this review

  1. References to studies included in this review
  2. References to studies excluded from this review
  3. References to ongoing studies
  4. Additional references
  5. References to other published versions of this review
Brannen 1997 {published data only}
  • Brannen AL, Still J, Haynes M, Orlet H, Rosenblum F, Law E, et al. A randomized prospective trial of hyperbaric oxygen in a referral burn center population. The American Surgeon 1997;63(3):205-8.
Hart 1974 {published data only}
  • Hart GB, O'Reilly RR, Broussard ND, Cave RH, Goodman DB, Yanda RL. Treatment of burns with hyperbaric oxygen. Surgery, Gynecology and Obstetrics 1974;139(5):693-6.
Jian 2011 {published data only}
  • Jian W, Liang D. Zhang H. Shang W, Wang P, Li W. The effect of hyperbaric oxygen therapy on treatment of late healed wounds after pharyngeal and laryngeal surgery. Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi 2011;25(1):14-15.
Niezgoda 1997 {published data only}
  • Niezgoda JA, Cianci P, Folden BW, Ortega RL, Slade JB, Storrow AB. The effect of hyperbaric oxygen therapy on a burn wound model in human volunteers. Plastic and Reconstructive Surgery 1997;99(6):1620-5.
Xu N 1999 {published data only}
  • Xu N, Li Z, Luo X. Effects of hyperbaric oxygen therapy on the changes in serum sIL-2R and Fn in severe burn patients. Zhonghua Zheng Xing Shao Shang Wai Ke Za Zhi 1999;15(3):220-3.

References to ongoing studies

  1. References to studies included in this review
  2. References to studies excluded from this review
  3. References to ongoing studies
  4. Additional references
  5. References to other published versions of this review
Brismar {published data only}
  • NCT01002209Postoperative Hyperbaric Oxygen Treatments to Reduce Complications in Diabetic Patients Undergoing Vascular Surgery (HODiVA). Ongoing study October 2009 - Anticipated end date: October 2014.
Millar {published data only}
  • NCT00264511Hyperbaric Oxygen in Lower Leg Trauma. Ongoing study February 2006 - Anticipated end date: December 2013.
Sires {published data only}
  • NCT01605110 Effects of Hyperbaric Oxygen Therapy on Surgical Wound Healing (BLEPH). Ongoing study August 2011 - Anticipated end date: November 2013.

Additional references

  1. References to studies included in this review
  2. References to studies excluded from this review
  3. References to ongoing studies
  4. Additional references
  5. References to other published versions of this review
Altman 2001
  • Altman DG, Schulz KF. Statistics notes: concealing treatment allocation in randomised trials. BMJ 2001;323(7310):446-7.
Bennett 2005a
  • Bennett MH, Feldmeier J, Hampson N, Smee R, Milross C. Hyperbaric oxygen therapy for late radiation tissue injury. Cochrane Database of Systematic Reviews 2005, Issue 3. [DOI: 10.1002/14651858.CD005005.pub2]
Bennett 2005b
Bennett 2008
Boerema 1964
Boerema 1965
Deeks 2011
  • Deeks JJ, Higgins JPT and Altman DG on behalf of the Cochrane Statistical Methods Group and the Cochrane Bias Methods Group (Editors). Chapter 9: Analysing data and undertaking meta-analyses. In: Higgins JPT, Green S (editors). Cochrane Handbook for Systematic Reviews of Interventions Version 5.1.0 [updated March 2011]. The Cochrane Collaboration, 2011. Available from www.cochrane-handbook.org.
Eskes 2010
Eskes 2012
  • Eskes AM, Brölmann FE, Sumpio BE, Mayer D, Moore Z, Agren MS, et al. Fundamentals of randomized clinical trials in wound care: design and conduct. Wound Repair and Regeneration 2012;20(4):449-55.
FDA 2006
  • Food, Drug Administration. Guidance for Industry - Chronic Cutaneous Ulcer and Burn Wounds - Developing Products for Treatment. http://www.fda.gov/downloads/Drugs/GuidanceComplianceRegulatoryInformation/Guidances/ucm071324.pdf 2006.
Franz 2007
Goldman 2009
Hess 2003
  • Hess CL, Howard MA, Attinger CE. A review of mechanical adjuncts in wound healing: hydrotherapy, ultrasound, negative pressure therapy, hyperbaric oxygen, and electrostimulation. Annals of Plastic Surgery 2003;51(2):210-8.
Higgins 2011
  • Higgins JPT, Altman DG, Sterne JAC on behalf of the Cochrane Statistical Methods Group and the Cochrane Bias Methods Group (Editors). Chapter 8: Assessing risk of bias in included studies. In: Higgins JPT, Green S (editors). Cochrane Handbook for Systematic Reviews of Interventions Version 5.1.0 [updated March 2011]. The Cochrane Collaboration, 2011. Available from www.cochrane-handbook.org.
Ioannidis 2008
Jull 2008
Kindwall 2002
  • Kindwall EP. Hyperbaric Medicine Practice. 2nd Edition. Best Publishing Company, 2002:4-8.
Kranke 2012
Lazarus 1994
  • Lazarus GS, Cooper DM, Knighton DR, Margolis DJ, Pecoraro RE, Rodeheaver G, et al. Definitions and guidelines for assessment of wounds and evaluation of healing. Archives of Dermatology 1994;130(4):489-93.
Lefebvre 2011
  • Lefebvre C, Manheimer E, Glanville J. Chapter 6: Searching for studies. In: Higgins JPT, Green S (editors). Cochrane Handbook for Systematic Reviews of Interventions Version 5.1.0 [updated March 2011]. The Cochrane Collaboration, 2011. Available from www.cochrane-handbook.org.
MacFarlane 2001
Niinikoski 2003
RevMan 2011
  • The Nordic Cochrane Centre, The Cochrane Collaboration. Review Manager (RevMan). 5.1.7. Copenhagen: The Nordic Cochrane Centre, The Cochrane Collaboration, 2008.
Roeckl-Wiedmann 2005
Ruiz-Canela 2000
Schulz 2002a
Schulz 2002b
Sign 2012
  • Scottish Intercollegiate Guidelines Network (SIGN). Search filters. http://www.sign.ac.uk/methodology/filters.html#random (accessed 6 November 2012).
Ubbink 1997
  • Ubbink DT, Tulevski II, den Hartog D, Koelemay MJ, Legemate DA, Jacobs MJ. The value of non-invasive techniques for the assessment of critical limb ischaemia. European Journal of Vascular and Endovascular Surgery 1997;13(3):296-300.
Vermeulen 2004
  • Vermeulen H, Ubbink D, Goossens A, de Vos R, Legemate D. Dressings and topical agents for surgical wounds healing by secondary intention. Cochrane Database of Systematic Reviews 2004, Issue 2. [DOI: 10.1002/14651858.CD003554.pub2]
Villanueva 2004
  • Villanueva E, Bennett MH, Wasiak J, Lehm JP. Hyperbaric oxygen therapy for thermal burns. Cochrane Database of Systematic Reviews 2004, Issue 3. [DOI: 10.1002/14651858.CD004727.pub2]
Wang 2003

References to other published versions of this review

  1. References to studies included in this review
  2. References to studies excluded from this review
  3. References to ongoing studies
  4. Additional references
  5. References to other published versions of this review
Eskes 2011
  • Eskes AM,   Ubbink DT,   Lubbers MJ,   Lucas C,   Vermeulen H. Hyperbaric oxygen therapy: solution for difficult to heal acute  wounds? Systematic review. World Journal of Surgery 2011;35(3):535-42.