Intervention Review

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Pharmacological interventions for hypertension in children

  1. Swasti Chaturvedi1,*,
  2. Deborah H Lipszyc2,
  3. Christoph Licht3,
  4. Jonathan C Craig4,
  5. Rulan Parekh5

Editorial Group: Cochrane Hypertension Group

Published Online: 1 FEB 2014

Assessed as up-to-date: 11 OCT 2013

DOI: 10.1002/14651858.CD008117.pub2


How to Cite

Chaturvedi S, Lipszyc DH, Licht C, Craig JC, Parekh R. Pharmacological interventions for hypertension in children. Cochrane Database of Systematic Reviews 2014, Issue 2. Art. No.: CD008117. DOI: 10.1002/14651858.CD008117.pub2.

Author Information

  1. 1

    Christian Medical College, Department of Paediatrics, Vellore, Tamil Nadu, India

  2. 2

    Hospital for Sick Children, Institute of Medical Science, Toronto, ON, Canada

  3. 3

    Hospital for Sick Children, Department of Nephrology, Toronto, ON, Canada

  4. 4

    The University of Sydney, Sydney School of Public Health, Sydney, NSW, Australia

  5. 5

    Hospital for Sick Children, Department of Paediatrics, Toronto, ON, Canada

*Swasti Chaturvedi, Department of Paediatrics, Christian Medical College, Ida Scudder Road, Vellore, Tamil Nadu, 632004, India. swasti.chaturvedi@gmail.com.

Publication History

  1. Publication Status: New
  2. Published Online: 1 FEB 2014

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[Figure 1]
Figure 1. Study flow diagram.
[Figure 2]
Figure 2. 'Risk of bias' graph: review authors' judgements about each methodological quality item presented as percentages across all included studies.
[Figure 3]
Figure 3. 'Risk of bias' summary: review authors' judgements about each risk of bias item for each included study.
[Figure 4]
Figure 4. Forest plot of comparison: 1 Antihypertensive drug class versus placebo, outcome: 1.1 Systolic blood pressure.
[Figure 5]
Figure 5. Forest plot of comparison: 1 Antihypertensive drug class versus placebo, outcome: 1.2 Diastolic blood pressure.
[Figure 6]
Figure 6. Forest plot of comparison: 2 Drug different doses, outcome: 2.1 SBP.
[Figure 7]
Figure 7. Forest plot of comparison: 2 Drug different doses, outcome: 2.2 DBP.
[Analysis 1.1]
Analysis 1.1. Comparison 1 Antihypertensive drug class versus placebo, Outcome 1 Systolic blood pressure.
[Analysis 1.2]
Analysis 1.2. Comparison 1 Antihypertensive drug class versus placebo, Outcome 2 Diastolic blood pressure.
[Analysis 2.1]
Analysis 2.1. Comparison 2 Antihypertensive drug dose response, Outcome 1 Systolic blood pressure.
[Analysis 2.2]
Analysis 2.2. Comparison 2 Antihypertensive drug dose response, Outcome 2 Diastolic blood pressure.