Intervention Protocol

Aspirin desensitisation therapy for aspirin-intolerant chronic rhinosinusitis

  1. Sriram Vaidyanathan1,*,
  2. Simon McKean2,
  3. Brian J Lipworth3

Editorial Group: Cochrane Ear, Nose and Throat Disorders Group

Published Online: 7 OCT 2009

DOI: 10.1002/14651858.CD008124

Database Title

Additional Information

How to Cite

Vaidyanathan S, McKean S, Lipworth BJ. Aspirin desensitisation therapy for aspirin-intolerant chronic rhinosinusitis (Protocol). Cochrane Database of Systematic Reviews 2009, Issue 4. Art. No.: CD008124. DOI: 10.1002/14651858.CD008124.

Author Information

  1. 1

    Ninewells Hospital and Medical School, Asthma and Allergy Research Group, Medicine and Therapeutics, Dundee, UK

  2. 2

    Ninewells Hospital and Medical School, ENT Surgery, Dundee, UK

  3. 3

    Ninewells Hospital and Medical School, Asthma and Allergy Research Group, Dundee, UK

*Sriram Vaidyanathan, Asthma and Allergy Research Group, Medicine and Therapeutics, Ninewells Hospital and Medical School, Dundee, DD1 9SY, UK. s.vaidyanathan@dundee.ac.uk.

Publication History

  1. Publication Status: New
  2. Published Online: 7 OCT 2009

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Abstract

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  2. Abstract

This is the protocol for a review and there is no abstract. The objectives are as follows:

To assess the effectiveness of oral, inhaled or intranasal aspirin desensitisation, as monotherapy or as adjunctive therapy, in adult patients with aspirin intolerant chronic rhinosinusitis, with or without concomitant asthma. We will evaluate subjective and objective parameters of nasal and lower airway function, quality of life and adverse event profiles.

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