Anti-angiogenic therapy for high grade glioma

  • Protocol
  • Intervention

Authors


Abstract

This is the protocol for a review and there is no abstract. The objectives are as follows:

To evaluate the efficacy and toxicity of anti-angiogenic therapy, either alone or in combination with chemotherapy and/or radiotherapy in patients with HGG.  Comparisons will be as follows:

  1. Newly diagnosed HGG treated with radiotherapy and chemotherapy in combination with angiogenesis inhibitor versus without angiogenesis inhibitors.

  2. First relapse therapy with angiogenesis inhibitor versus without angiogenesis inhibitors.

  3. Second or third line angiogenesis inhibitors versus therapy without angiogenesis inhibitors.