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Intranasal ipratropium bromide for the common cold

  1. Zaina H AlBalawi1,*,
  2. Sahar S Othman2,
  3. Khalid AlFaleh3

Editorial Group: Cochrane Acute Respiratory Infections Group

Published Online: 19 JUN 2013

Assessed as up-to-date: 9 APR 2013

DOI: 10.1002/14651858.CD008231.pub3


How to Cite

AlBalawi ZH, Othman SS, AlFaleh K. Intranasal ipratropium bromide for the common cold. Cochrane Database of Systematic Reviews 2013, Issue 6. Art. No.: CD008231. DOI: 10.1002/14651858.CD008231.pub3.

Author Information

  1. 1

    University of Alberta, Department of Medicine, Edmonton, Alberta, Canada

  2. 2

    College of Medicine, King Abdulaziz University Hospital, Department of Family and Community Medicine, Jeddah, western, Saudi Arabia

  3. 3

    King Saud University, Department of Pediatrics (Division of Neonatology), Riyadh, Saudi Arabia

*Zaina H AlBalawi, Department of Medicine, University of Alberta, 11106 83 ave, Edmonton, Alberta, T6G0V1, Canada. Zaina.albalawi@ualberta.ca. Zaina7rb@yahoo.com.

Publication History

  1. Publication Status: New search for studies and content updated (no change to conclusions)
  2. Published Online: 19 JUN 2013

SEARCH

References

References to studies included in this review

  1. References to studies included in this review
  2. References to studies excluded from this review
  3. Additional references
  4. References to other published versions of this review
Borum 1981 {published data only}
  • Borum P, Olsen L, Winther B, Mygind N. Ipratropium nasal spray: a new treatment for rhinorrhea in the common cold. American Review of Respiratory Disease 1981;123:418-20.
Diamond 1995 {published data only}
  • Diamond L, Dockhorn R, Grossman J, Kisicki J, Posner M, Zinny M, et al. A dose-response study of the efficacy and safety of ipratropium bromide nasal spray in the treatment of the common cold. Journal of Allergy and Clinical Immunology 1995;95:1139-46.
Dockhorn 1992 {published data only}
  • Dockhorn R, Grossman J, Posner M, Zinny M, Tinkleman D. A double-blind, placebo-controlled study of the safety and efficacy of ipratropium bromide nasal spray versus placebo in patients with the common cold. Journal of Allergy and Clinical Immunology 1992;90:1076-82.
Eccles 2007 {published data only}
  • Eccles R, Pedersen A, Regberg D, Tulento H, Borum P, Stjärne P. Efficacy and safety of topical combinations of ipratropium and xylometazoline for the treatment of symptoms of runny nose and nasal congestion associated with acute upper respiratory tract infection. American Journal of Rhinology 2007;21:40-5.
Gaffey 1988 {published data only}
  • Gaffey M, Hayden F, Boyd J, Gwaltney J. Ipratropium bromide treatment of experimental rhinovirus infection. Antimicrobial Agents and Chemotherapy 1988;32:1644-7.
Hayden 1996 {published data only}
  • Hayden F, Diamond L, Wood P, Korts D, Wecker M. Effectiveness and safety of intranasal ipratropium bromide in common colds. Annals of Internal Medicine 1996;125:89-97.
Østberg 1997 {published data only}
  • Østberg B, Winther B, Borum P, Mygind N. Common cold and high-dose ipratropium bromide: use of anticholinergic medication as an indicator of reflex-mediated hypersecretion. Rhinology 1997;35(2):58-62.

References to studies excluded from this review

  1. References to studies included in this review
  2. References to studies excluded from this review
  3. Additional references
  4. References to other published versions of this review
Kim 2005 {published data only}
  • Kim KT, Kerwin E, Landwehr L, Bernstein JA, Bruner D, Harris D, et al. Use of 0.06% ipratropium bromide nasal spray in children aged 2 to 5 years with rhinorrhea due to a common cold or allergies. Annals of Allergy Asthma and Immunology 2005;94(1):73-9.
Pitkäranta 1998 {published data only}
  • Pitkäranta A, Wecker MT, Korts DC, Hayden FG. Combined intranasal ipratropium bromide and oxymetazoline in experimental rhinovirus infection. American Journal of Rhinology 1998;12(2):125-9.

Additional references

  1. References to studies included in this review
  2. References to studies excluded from this review
  3. Additional references
  4. References to other published versions of this review
Arroll 2013
Eccles 2010
  • Eccles R, Martensson K, Chen S. Effects of intranasal xylometazoline, alone or in combination with ipratropium, in patients with common cold. Current Medical Research & Opinion 2010;26(4):889-99.
Egger 1997
  • Egger M, Davey-Smith G, Schneider M, Minder C. Bias in meta-analysis detected by a simple, graphical test. BMJ 1997;315(7109):629-34.
Fendrick 2003
  • Fendrick AM, Monto AS, Nightengale B, Sarnes M. The economic burden of non-influenza-related viral respiratory tract infection in the United States. Archives of Internal Medicine 2003;163(4):487-94.
Graf 2009
Guyatt 1991
  • Guyatt G, Patrick D, Feeny D. Glossary. Controlled Clinical Trials 1991; Vol. 12, issue Suppl:274-80.
Heikkinen 2003
Hemilä 2013
Higgins 2011
  • Higgins JPT, Altman DG (editors). Chapter 8: Assessing risk of bias in included studies. In: Higgins JPT, Green S (editors). Cochrane Handbook for Systematic Reviews of Interventions Version 5.1.0 [updated March 2011]. The Cochrane Collaboration. Available from www.cochrane-handbook.org 2011.
Jackson 1958
  • Jackson GG, Dowling HF, Spiesman IG, Boand AV. Transmission of the common cold to volunteers under controlled conditions. 1. The common cold as a clinical entity. Archives of Internal Medicine 1958;101:267-8.
Kim 2009
Lefebvre 2011
  • Lefebvre C, Manheimer E, Glanville J. Chapter 6: Searching for studies. In: Higgins JPT, Green S editor(s). Cochrane Handbook for Systematic Reviews of Interventions. Chichester, UK: Wiley-Blackwell, 2011.
Patrick 1993
  • Patrick DL, Erickson P. Health Status and Health Policy. Quality of Life in Health Care Evaluation and Resource Allocation. New York and Oxford: Oxford University Press, 1993.
Singh 2011
Stewart 1992
  • Stewart AL, Ware JE Jr. Measuring Functioning and Well-being: the Medical Outcomes Study Approach. Durham and London: Duke University Press, 1992.
Toft 1982
Tyrrell 1993
  • Tyrrell DA, Cohen S, Schlarb JE. Signs and symptoms in common colds. Epidemiology and Infection 1993;111(1):143-56.
Zhang 2009

References to other published versions of this review

  1. References to studies included in this review
  2. References to studies excluded from this review
  3. Additional references
  4. References to other published versions of this review
AlBalawi 2011