Blood pressure targets for hypertension in patients with diabetes mellitus

  • Protocol
  • Intervention

Authors

  • Jose Agustin Arguedas,

    Corresponding author
    1. Universidad de Costa Rica, Depto de Farmacologia Clinica, Facultad de Medicina, San Pedro de Montes de Oca, Costa Rica
    • Jose Agustin Arguedas, Depto de Farmacologia Clinica, Facultad de Medicina, Universidad de Costa Rica, San Pedro de Montes de Oca, Costa Rica. drarguedas@ampmd.com.

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  • Viriam Leiva,

    1. University of Costa Rica, Escuela de Enfermeria, Facultad de Medicina, San Jose, Costa Rica
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  • James M Wright

    1. University of British Columbia, Department of Anesthesiology, Pharmacology and Therapeutics, Vancouver, BC, Canada
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Abstract

This is the protocol for a review and there is no abstract. The objectives are as follows:

Primary objective

To determine if there is a reduction in total mortality and morbidity associated with treatment of blood pressure to "lower targets" as compared with "standard targets" in the management of patients with diabetes mellitus and elevated arterial blood pressure.  "Lower targets" are defined as blood pressure targets less than or equal to 130/80 mmHg.  "Standard targets" are defined as blood pressure targets less than or equal to 140-160 mmHg systolic and/or blood pressure targets less than or equal to 90-100 mmHg diastolic. 

Secondary objectives

  1. To determine if there is a change in mean achieved systolic and diastolic blood pressure associated with "lower targets" as compared with "standard targets" in patients with diabetes with elevated blood pressure.  

  2. To determine if there is a change in withdrawals due to adverse events with "lower targets" as compared with "standard targets", in patients with diabetes with elevated blood pressure.