Intervention Protocol

Blood pressure targets for hypertension in patients with diabetes mellitus

  1. Jose Agustin Arguedas1,*,
  2. Viriam Leiva2,
  3. James M Wright3

Editorial Group: Cochrane Hypertension Group

Published Online: 20 JAN 2010

Assessed as up-to-date: 29 OCT 2009

DOI: 10.1002/14651858.CD008277

Database Title

Additional Information

How to Cite

Arguedas JA, Leiva V, Wright JM. Blood pressure targets for hypertension in patients with diabetes mellitus (Protocol). Cochrane Database of Systematic Reviews 2010, Issue 1. Art. No.: CD008277. DOI: 10.1002/14651858.CD008277.

Author Information

  1. 1

    Universidad de Costa Rica, Depto de Farmacologia Clinica, Facultad de Medicina, San Pedro de Montes de Oca, Costa Rica

  2. 2

    University of Costa Rica, Escuela de Enfermeria, Facultad de Medicina, San Jose, Costa Rica

  3. 3

    University of British Columbia, Department of Anesthesiology, Pharmacology and Therapeutics, Vancouver, BC, Canada

*Jose Agustin Arguedas, Depto de Farmacologia Clinica, Facultad de Medicina, Universidad de Costa Rica, San Pedro de Montes de Oca, Costa Rica. drarguedas@ampmd.com.

Publication History

  1. Publication Status: New
  2. Published Online: 20 JAN 2010

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Abstract

  1. Top of page
  2. Abstract

This is the protocol for a review and there is no abstract. The objectives are as follows:

Primary objective

To determine if there is a reduction in total mortality and morbidity associated with treatment of blood pressure to "lower targets" as compared with "standard targets" in the management of patients with diabetes mellitus and elevated arterial blood pressure.  "Lower targets" are defined as blood pressure targets less than or equal to 130/80 mmHg.  "Standard targets" are defined as blood pressure targets less than or equal to 140-160 mmHg systolic and/or blood pressure targets less than or equal to 90-100 mmHg diastolic. 

Secondary objectives

  1. To determine if there is a change in mean achieved systolic and diastolic blood pressure associated with "lower targets" as compared with "standard targets" in patients with diabetes with elevated blood pressure.  
  2. To determine if there is a change in withdrawals due to adverse events with "lower targets" as compared with "standard targets", in patients with diabetes with elevated blood pressure. 

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