Intervention Review

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Topiramate for neuropathic pain and fibromyalgia in adults

  1. Philip J Wiffen1,
  2. Sheena Derry1,*,
  3. Michael PT Lunn2,
  4. R Andrew Moore1

Editorial Group: Cochrane Neuromuscular Disease Group

Published Online: 30 AUG 2013

Assessed as up-to-date: 8 MAY 2013

DOI: 10.1002/14651858.CD008314.pub3


How to Cite

Wiffen PJ, Derry S, Lunn MPT, Moore RA. Topiramate for neuropathic pain and fibromyalgia in adults. Cochrane Database of Systematic Reviews 2013, Issue 8. Art. No.: CD008314. DOI: 10.1002/14651858.CD008314.pub3.

Author Information

  1. 1

    University of Oxford, Pain Research and Nuffield Department of Clinical Neurosciences, Oxford, Oxfordshire, UK

  2. 2

    National Hospital for Neurology and Neurosurgery, Department of Neurology and MRC Centre for Neuromuscular Diseases, London, UK

*Sheena Derry, Pain Research and Nuffield Department of Clinical Neurosciences, University of Oxford, Pain Research Unit, Churchill Hospital, Oxford, Oxfordshire, OX3 7LE, UK. sheena.derry@ndcn.ox.ac.uk.

Publication History

  1. Publication Status: New
  2. Published Online: 30 AUG 2013

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References

References to studies included in this review

  1. References to studies included in this review
  2. References to studies excluded from this review
  3. References to studies awaiting assessment
  4. Additional references
Khoromi 2005 {published data only}
NCT00231673 {published data only}
  • Freeman R. A double-blind, placebo-controlled, parallel group study to evaluate the effect of topiramate on electrophysiologic parameters in subjects with diabetic peripheral polyneuropathy. apps.who.int/trialsearch/Trial.aspx?TrialID=NCT00231673 (accessed 9 May 2013).
Raskin 2004 {published data only}
  • Raskin P, Donofrio PD, Rosenthal NR, Hewitt DJ, Jordan DM, Xiang J, et al (CAPSS-141 Study Group). Topiramate vs placebo in painful diabetic neuropathy: analgesic and metabolic effects. Neurology 2004;63(5):865-73. [DOI: 10.1212/01.WNL.0000137341.89781.14; PUBMED: 15365138]
Thienel 2004 {published data only}

References to studies excluded from this review

  1. References to studies included in this review
  2. References to studies excluded from this review
  3. References to studies awaiting assessment
  4. Additional references
Edwards 1998 {published data only}
  • Edwards KR, Glantz MJ, Levin P. An evaluation of topiramate in the management of painful diabetic neuropathy. American Pain Society 17th Annual Scientific Meeting, San Diego November 5-8. 1998.
Edwards 2000 {published data only}
  • Edwards KR, Glantz MJ, Button J, Norton JA, Whittaker T, Cross N. Efficacy and safety of topiramate in the treatment of painful diabetic neuropathy: a double-blind, placebo-controlled study. Neurology. 2000; Vol. 54 (Suppl 3):A81.
Muehlbacher 2006 {published data only}
Vinik 2003 {published data only}
  • Vinik A, Hewitt D, Xiang J, Jordan D, Rosenthal N. Topiramate in the treatment of painful diabetic neuropathy: results from a multicenter, randomized, double-blind, placebo-controlled trial. Neurology. 2003; Vol. 60 (Suppl 1):A154-5.

References to studies awaiting assessment

  1. References to studies included in this review
  2. References to studies excluded from this review
  3. References to studies awaiting assessment
  4. Additional references
NCT00001725 {published data only}
  • National Institute of Dental and Craniofacial Research (NIDCR). Studies of dextromethorphan and topiramate to treat oral and facial pain. clinicaltrials.gov/show/NCT00001725 2002 (accessed 9 May 2013).
Wang 2011 {published data only}
  • Wang QP, Bai M. Topiramate versus carbamazepine for the treatment of classical trigeminal neuralgia: a meta-analysis. CNS Drugs 2011;25(10):847-57. [DOI: 10.2165/11595590-000000000-00000; PUBMED: 21936587]

Additional references

  1. References to studies included in this review
  2. References to studies excluded from this review
  3. References to studies awaiting assessment
  4. Additional references
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