Oral zinc for the prevention of hyperbilirubinemia in neonates

  • Protocol
  • Intervention



This is the protocol for a review and there is no abstract. The objectives are as follows:

1. To determine the effect of oral zinc supplementation compared to placebo or no treatment on the incidence of hyperbilirubinemia in neonates during the first week of age.

Comparison will include:

  • term vs. preterm neonates;

  • all neonates vs. neonates at risk of hyperbilirubinemia;

  • low dose (≤ 10 mg) vs. higher dose of the oral zinc;

  • lesser (< 72 h) vs. greater (≥ 72 h) duration of treatment.

2. To assess the safety of the oral zinc in enrolled neonates.